POM-V Prescription Required Companion Animal

Sulfatrim (16 mg/ml + 80 mg/ml) Oral Drops

Active ingredients: Sulfamethoxazole, Trimethoprim

Form

Drops

Species

Bearded Dragon Pigeon (non-food producing) Rabbits

Manufacturer

Alfasan Nederland B.V.

VMD MA No.

36408/4008

What it's used for

Treatment of gastrointestinal infections caused by protozoa (namely coccidian) sensitive to the combination of trimethoprim and sulfamethoxazole.

Full indications, dosage and side effects ↓

View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Sulfamethoxazole + Trimethop...

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

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Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Sulfatrim (16 mg/ml + 80 mg/ml) Oral Drops — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 26 Mar 2026.

Treatment of gastrointestinal infections caused by protozoa (namely coccidian)
sensitive to the combination of trimethoprim and sulfamethoxazole.

For oral administration.
To ensure a correct dosage, bodyweight should be determined as accurately as
possible to avoid under-dosing.

Revised: July 2023
AN: 01208/2023
SpeciesDose (mg/kg)
TMP+SMZ
Frequency
daily
ml solution/kgDurations
(days)
Rabbit20 - 3020.2 – 0.310 - 14Pigeon25 - 5020.2 – 0.510 - 14Bearded
dragon
15 – 201*0.15 – 0.27 – 14
* Some literature advises alternate day dosing after the second dose has been
administered.
This is a limited marketing authorisation and the above dosages are in accordance
with those reported for the active substances in the target species. Any suspected
adverse events or suspected lack of efficacy must be reported to the Marketing
Authorisation Holder or the Veterinary Medicines Directorate

Do not use in cases with severe renal or hepatic impairment.
Do not use the product for prophylaxis.
Do not use in cases of known hypersensitivity to the active substances or the
excipients.

Sulfonamides can cause various hypersensitivity reactions or signs of gastrointestinal
disease by altering the normal gut flora.Regurgitation may be seen in birds.
CNS stimulation and myelin degeneration have been noted after very high dosages.

This is a limited marketing authorisation and efficacy of the product is supported
by a very small amount of data for the above indications. Suspected lack of
efficacy of the product must be reported to the Marketing Authorisation Holder or the
Veterinary Medicines Directorate.
As with all other anti-infectives, prolonged use may result in the development of resistant
strains.

Revised: July 2023
AN: 01208/2023

Special precautions for use in animals
Maintain patient hydration during treatment.
The product should be used with caution in patients with diminished renal or
hepatic function, or urinary obstruction, due to the possible increased risk of side
effects as a result of decreased drug clearance.
Special precautions to be taken by the person administering the veterinary
medicinal product to animals
People with known hypersensitivity to sulfonamides should avoid contact with the
veterinary medicinal product.
In case of reaction of hypersensitivity after exposure (such as skin rash), seek
medical advice and show the package leaflet or the label to the physician. In case of
severe reactions (swelling of the face, lips or eyes), seek prompt medical attention
and take the package leaflet with you.
Take care to avoid direct contact with skin and eyes. If contact occurs, wash affected
area with copious amounts of clean water. Seek medical advice if irritation persists.
Wash hands after use.

Antacids may decrease the oral bioavailability of sulfonamides if administered
concurrently.
Sulfonamides may give false-positive results for urine glucose determinations when
using the Benedict's method.

Do not store above 25C.
Do not refrigerate or freeze.
Protect from light.
Store in the original container.
Following dilution in tap water, any medicated water remaining after 4 hours should be
discarded.

Do not use the product in animals intended for human consumption or in those
animals producing eggs for human consumption.
5.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.