Methoxasol 20/100 mg/ml Solution for Use in Drinking Water for Pigs and Chickens

Severely diseased animals can have a decreased appetite and water consumption. If
necessary the concentration of the veterinary medicinal product in the drinking water
may need to be adjusted to make sure that the recommended dosage is being
consumed. However if the concentration of the veterinary medicinal product is
increased too much, the intake of the medicated drinking water decreases for
palatability reasons. Therefore water intake should be monitored regularly, especially
in broilers.
In case of insufficient intake of water, pigs should be treated parenterally.

Special precautions for use in animals
Due to the likely variability (time, geographical) in susceptibility of bacteria for
potentiated sulphonamides, occurrence of resistance of bacteria may differ from
country to country and even from farm to farm, and therefore bacteriological sampling
and susceptibility testing are recommended. Use of the veterinary medicinal product
should be based on culture and sensitivity of micro-organisms from diseased cases
on farm or from recent previous experience on the farm. Use of the veterinary
medicinal product deviating from the instructions given in the SPC may increase the
prevalence of bacteria resistant to sulfamethoxazole and trimethoprim and may also
decrease the effectiveness of combinations of trimethoprim with other sulphonamides
due to the potential for cross resistance. Official and local antimicrobial policies
should be taken into account when the veterinary medicinal product is used.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
This veterinary medicinal product contains sulfamethoxazole, which can cause
allergic reactions in some people.
People with known hypersensitivity (allergy) to sulphonamides or trimethoprim should
avoid contact with the veterinary medicinal product.
During preparation and administration of the medicated drinking water, skin contact
with the drug should be avoided. Therefore it is recommended to wear impermeable
gloves e.g. rubber or latex when applying the veterinary medicinal product. Do not
handle this veterinary medicinal product if you know you are allergic to trimethoprim
or sulphonamides.
Do not smoke, drink or eat when handling the veterinary medicinal product.
If you develop symptoms following exposure to the veterinary medicinal product such
as skin rash, you should seek medical advice and show the present warning to the
doctor. Swelling of the face, lips or eyes or difficulty with breathing are more serious
symptoms and require urgent medical attention.
This veterinary medicinal product can cause eye-irritation.
Always wear protective glasses when mixing the veterinary medicinal product with
drinking water.
In the event of eye contact, rinse the eye with copious amounts of clean water and if
irritation occurs, seek medical attention. In the event of accidental ingestion, seek
medical advice. Wash hands and contaminated skin immediately after handling the
veterinary medicinal product.

Revised: December 2023
AN: 04060/2022
Laboratory studies in rabbits and rats conducted with the excipient N-methyl
pyrrolidone have shown evidence of foetotoxic effects. The veterinary medicinal
product should not be administered by pregnant women and women suspected of
being pregnant. Personal protective equipment consisting of gloves should be worn
when handling the veterinary medicinal product by women of childbearing age.
Special precautions for the protection of the environment
Not applicable.
Other precautions
Not applicable.