Methoxasol 20/100 mg/ml Solution for Use in Drinking Water for Pigs and Chickens

Severely diseased animals can have a decreased appetite and water consumption. If
necessary the concentration of the veterinary medicinal product in the drinking water may
need to be adjusted to make sure that the recommended dosage is being consumed.
However if the concentration of the veterinary medicinal product is increased too much,
the intake of the medicated drinking water decreases for palatability reasons. Therefore
water intake should be monitored regularly, especially in broilers.
In case of insufficient intake of water, pigs should be treated parenterally.

Special precautions for safe use in the target species:
Due to the likely variability (time, geographical) in susceptibility of bacteria for potentiated
sulphonamides, occurrence of resistance of bacteria
and even from farm to farm, and therefore bacteriological sampling and susceptibility
testing are recommended. Use of the veterinary medicinal product should be based on
culture and sensitivity of micro-organisms from diseased cases on farm or from recent
previous experience on the farm. Use of the veterinary medicinal product deviating from
the instructions given in the SPC may increase the prevalence of bacteria resistant to
sulfamethoxazole and trimethoprim and may also decrease the effectiveness of
combinations of trimethoprim with other sulphonamides due to the potential for cross
resistance. Official and local antimicrobial policies should be taken into account when the
veterinary medicinal product is used.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
This veterinary medicinal product contains sulfamethoxazole, which can cause allergic
reactions in some people.
People with known hypersensitivity (allergy) to sulphonamides or trimethoprim should
avoid contact with the veterinary medicinal product.
During preparation and administration of the medicated drinking water, skin contact with
the drug should be avoided. Personal protective equipment consisting of impermeable
gloves e.g. rubber or latex should be worn when handling the veterinary medicinal product.
Do not handle this veterinary medicinal product if you know you are allergic to trimethoprim
or sulphonamides.
Do not smoke, drink or eat when handling the veterinary medicinal product.
If you develop symptoms following exposure to the veterinary medicinal product such as
skin rash, you should seek medical advice and show the package leaflet or the label to the
physician. Swelling of the face, lips or eyes or difficulty with breathing are more serious
symptoms and require urgent medical attention.
This veterinary medicinal product can cause eye-irritation.
Personal protective equipment consisting of safety glasses should be worn when mixing
the veterinary medicinal product with drinking water. In the event of eye contact, rinse the
eye with copious amounts of clean water and if irritation occurs, seek medical advice.
In the event of accidental ingestion, seek medical advice. Wash hands and contaminated
skin immediately after handling the veterinary medicinal product.
Laboratory studies in rabbits and rats conducted with the excipient N-methyl pyrrolidone
have shown evidence of foetotoxic effects. The veterinary medicinal product should not be
administered by pregnant women and women suspected of being pregnant. Personal
protective equipment consisting of gloves should be worn when handling the veterinary
medicinal product by women of childbearing age.
Special precautions for the protection of the environment:
Not applicable.