Vetmulin 125 mg/ml Solution for Use in Drinking Water for Pigs and Chickens

Guidance for preparing veterinary medicinal product solutions:
To ensure a correct dosage, body weight should be determined as accurately as possible.
The intake of medicated water depends on the clinical condition of the animals. In order to
obtain the correct dosage, the concentration of tiamulin may need to be adjusted
accordingly.
Based on the recommended dose and the number and weight of animals to be treated, the
exact daily concentration of the veterinary medicinal product should be calculated
according to the following formula:
ml veterinary medicinal product/ x average body weight (kg)
kg body weight/ day of animals to be treated ml veterinary medicinal product
___________________________________________________ = per litre of drinking water
average daily water intake (l/animal)
Use a sufficiently accurate commercially available device to measure the required amount
of veterinary medicinal product. Only use clean containers for preparation of the medicated
drinking water. Stir the medicated drinking water prepared with the veterinary medicinal
product for at least 1 minute after preparation in order to assure homogeneity.
When medicating large volumes of water, prepare a concentrated solution first and then
dilute to the required final concentration. The maximum solubility of the veterinary
medicinal product is 200 mL/L.
Medicated drinking water should be refreshed or replaced every 24 hours.
In order to avoid interactions between the ionophores and tiamulin, the veterinarian and
farmer should check that the feed label does not state that it contains salinomycin,
monensin and narasin.
For chickens, in order to avoid interactions between the incompatible ionophores
monensin, narasin and salinomycin and tiamulin, the feed mill supplying the birds feed

Revised January 2025
should be notified that tiamulin will be used and that these anticoccidials should not be
included in the feed or contaminate the feed.
The feed should be tested for the ionophores prior to use if there is any suspicion that
contamination of the feed might occur.
If an interaction does occur, stop tiamulin medication immediately and replace with fresh
drinking water. Remove contaminated feed as soon as possible and replace with feed not
containing the tiamulin- incompatible ionophores.
Pigs
-
The dosage is 8.8 mg tiamulin hydrogen fumarate/kg body weight (equivalent to 7 ml of
veterinary medicinal product/100 kg body weight) administered daily in the drinking water
of pigs for 3 to 5 consecutive days depending on the severity of the infection and/or the
duration of the disease.
-Brachyspira
pilosicoli. The dosage is 8.8 mg tiamulin hydrogen fumarate /kg body weight
(equivalent to 7 ml of veterinary medicinal product/100 kg body weight) administered
daily in the drinking water of pigs for 3 to 5 consecutive days depending on the
severity of the infection and/or the duration of the disease.
-Lawsonia
intracellularis. The dosage is 8.8 mg tiamulin hydrogen fumarate /kg body weight
(equivalent to 7 ml of veterinary medicinal product/100 kg body weight) administered
daily in the drinking water of pigs for 5 consecutive days.
-Mycoplasma
hyopneumoniae,including infections complicated by Pasteurella multocida
susceptible to tiamulin. The dosage is 20 mg tiamulin hydrogen fumarate/kg body
weight (equivalent to 16 ml of veterinary medicinal product/100 kg body weight)
administered daily for 5 consecutive days.
Chickens (layer hens)
For the treatment and metaphylaxis of Chronic Respiratory Disease caused by
Mycoplasma gallisepticum and Airsacculitis and Infectious Synovitis caused by
Mycoplasma synoviae. the dosage is 25 mg tiamulin hydrogen fumarate/kg body weight
(equivalent to 20 ml of veterinary medicinal product/100 kg body weight) administered
daily for the period of 3 to 5 consecutive days.