POM-V Prescription Required

Tialin 125 mg/ml Solution for Use in Drinking Water for Pigs, Chickens and Turkeys

Active ingredient: Tiamulin Hydrogen Fumarate

Form

Solution

Species

Chickens Pigs Turkeys

Manufacturer

Dechra Regulatory B.V.

VMD MA No.

50406/5041

What it's used for

Pigs: - Treatment of Swine Dysentery caused by Brachyspira hyodysenteriae susceptible to tiamulin. - Treatment of Porcine Colonic Spirochaetosis (colitis)...

Full indications, dosage and side effects ↓

View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Tiamulin Hydrogen Fumarate

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

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Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Tialin 125 mg/ml Solution for Use in Drinking Water for Pigs, Chickens and Turkeys — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

Pigs:
- Treatment of Swine Dysentery caused by Brachyspira hyodysenteriae
susceptible to tiamulin.
- Treatment of Porcine Colonic Spirochaetosis (colitis) caused by
pilosicoli susceptible to tiamulin.
- Treatment of Porcine Proliferative Enteropathy (ileitis) caused by Lawsonia
intracellularis susceptible to tiamulin.
- Treatment and metaphylaxis of Enzootic Pneumonia caused by Mycoplasma
hyopneumoniae, including infections complicated by Pasteurella multocida
susceptible to tiamulin.

Revised: May 2025
AN: 00168/2025
- Treatment of Pleuropneumonia caused by
susceptible to tiamulin.
The presence of the disease in the herd must be established before the
veterinary medicinal product is used.
Chickens:
Treatment and metaphylaxis of Chronic Respiratory Disease caused by
Mycoplasma gallisepticum and Airsacculitis and Infectious Synovitis caused by
Mycoplasma synoviae susceptible to tiamulin.
The presence of the disease in the flock must be established before the
veterinary medicinal product is used.
Turkeys:
Treatment and metaphylaxis of Infectious Sinusitis and Airsacculitis caused by
Mycoplasma gallisepticum, Mycoplasma synoviae and Mycoplasma meleagridis
susceptible to tiamulin.
The presence of the disease in the flock must be established before the
veterinary medicinal product is used.

Do not use in pigs and birds that could receive veterinary medicinal products
containing monensin, narasin or salinomycin during or for at least seven days
before or after treatment with tiamulin. Severe growth depression or death may
result.
Do not use in cases of hypersensitivity to the active substance or to any of the
excipients.
See section 4.8 for information regarding interaction between tiamulin and
ionophores.

Pigs:
Rare (1 to 10 animals / 10,000
animals treated)
Erythema, Skin oedemaVery rare
(<1 animal / 10,000 animals treated,
including isolated reports):
DeathUndetermined frequency (cannot be
estimated on the available data)
Apathy

Revised: May 2025
AN: 00168/2025
Chickens and Turkeys:
Undetermined frequency (cannot be
estimated on the available data)
Decreased drinking
a
a It appears to be concentration-dependent with 0.025% tiamulin reducing intake by approximately 15% in chickens and 20%
in turkeys. A concentration with 0.0125% tiamulin reduces intake by approximately 10% in chickens. It does not appear to
have any adverse effect on overall performance of the birds or efficacy of the product.
Reporting adverse events is important. It allows continuous safety monitoring of
a veterinary medicinal product. Reports should be sent, preferably via a
veterinarian, to either the marketing authorisation holder or its local
representative or the national competent authority via the national reporting
system. See the package leaflet for contact details.

Pigs with reduced water intake and/or in a debilitated condition should be
treated parenterally.
The water intake of birds should be monitored at frequent intervals during
treatment, especially in hot weather, because water intake may be depressed
during the administration of tiamulin. This appears to be a concentration-
dependent effect and does not appear to have any adverse effect on the overall
performance of the birds or efficacy of the veterinary medicinal product. 500 mg
tiamulin hydrogen fumarate in 4 litres of water may reduce intake by
approximately 10% and 500 mg tiamulin hydrogen fumarate in 2 litres of water
by 15% in chickens.

Revised: May 2025
AN: 00168/2025
In turkeys, this effect is more marked, with approximately a 20% reduction
observed and therefore it is recommended not to exceed a concentration of
500 mg tiamulin hydrogen fumarate in 2 litres of the drinking water.

i). Special precautions for use in animals
Use of the veterinary medicinal product should be based on susceptibility
testing of the bacteria isolated from the animal. If this is not possible, therapy
should be based on local (regional, farm level) epidemiological information
about susceptibility of target bacteria. In some European regions, an increasing
proportion of Brachyspira hyodysenteriae isolates from clinical cases
demonstrate significantly reduced in vitro susceptibility to tiamulin. Inappropriate
use of the veterinary medicinal product may increase the prevalence of bacteria
resistant to tiamulin.
ii). Special precautions to be taken by the person administering the veterinary
medicinal product to animals
This veterinary medicinal product may cause skin and eye irritation. When
mixing, direct contact with the skin and eyes should be avoided by wearing
impermeable rubber gloves and safety glasses.
In case of accidental eye contact, irrigate the eyes thoroughly with clean
running water immediately. Seek medical advice if irritation persists.
Contaminated clothing should be removed and any splashes on to the skin
should be washed off immediately.
Wash hands after use.
Special precautions for the protection of the environment:
Not applicable.
iii) Other precautions
Not applicable.

Tiamulin has been shown to interact with ionophores such as monensin,
salinomycin or narasin and may result in signs indistinguishable from an
ionophore toxicosis. Animals should not receive veterinary medicinal products
containing monensin, salinomycin or narasin during or at least 7 days before or
after treatment with tiamulin. Severe growth depression, ataxia, paralysis or
death may result
If signs of an interaction do occur, stop both the administration of tiamulin-
medicated drinking water and also the administration of ionophore-
contaminated feed immediately. The feed should be removed and replaced with
fresh feed not containing the anticoccidials monensin, salinomycin or narasin.
Concomitant use of tiamulin and the divalent ionophore anticoccidials lasalocid
and semduramicin do not appear to cause any interaction, however the
concomitant use of maduramicin may lead to a mild to moderate growth
depression in chickens. The situation is transient and recovery normally occurs
within 3 - 5 days following withdrawal of tiamulin treatment.

This veterinary medicinal product does not require any special storage
conditions.

Excipients:
Methyl parahydroxybenzoate (E218) 0.9 mg
Propyl parahydroxybenzoate 0.1 mg
Ethanol 96% 100.0 mg
For the full list of excipients, see section

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.