POM-V Prescription Required

Denagard 200 mg/ml Solution for Injection

Active ingredient: Tiamulin Hydrogen Fumarate

Form

Injection

Species

Pigs

Manufacturer

Elanco GmbH

VMD MA No.

52127/5080

What it's used for

Swine dysentery: For the treatment of swine dysentery caused by hyodysenteriae and complicated by Bacteroides spp and Fusobacterium spp. Enzootic pneumonia...

Full indications, dosage and side effects ↓

View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Tiamulin Hydrogen Fumarate

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Your prescription rights → VMD register of retailers →

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Denagard 200 mg/ml Solution for Injection — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

Swine dysentery: For the treatment of swine dysentery caused by
hyodysenteriae and complicated by Bacteroides spp and Fusobacterium spp.
Enzootic pneumonia complex of pigs: For the treatment of enzootic
pneumonia complex, caused by M. hyopneumoniae and where the secondary
bacteria are sensitive to tiamulin.
Mycoplasmal arthritis: For the treatment of arthritis caused by Mycoplasma
hyosynoviae, to reduce lameness and restore growth performance.

To be administered by intramuscular injection. Swab the rubber septum before
removing each dose. Use a dry, sterile, needle and syringe. The maximum
volume to be administered at any one intramuscular injection site should not
exceed 10 ml. Swine dysentery Treatment: The dose is 1 ml/20 kg bodyweight
(equivalent to 10 mg tiamulin hydrogen fumarate/kg body weight)
intramuscularly administered as a single treatment to pigs showing clinical
signs of the disease.
Follow-up treatment should be provided when necessary with either Denagard
12.5% w/v Concentrate for Oral Solution or Denagard 2% Premix for
Medicated Feedingstuff administered according to directions in the drinking
water or in the feed, respectively.

Revised: April 2025
AN: 04322/2024
Enzootic pneumonia complex of pigs Treatment: The dose is 1.5 ml/20 kg
bodyweight (equivalent to 15 mg tiamulin hydrogen fumarate/kg body weight)
administered intramuscularly for a period of 3 consecutive days to pigs
showing clinical signs of the disease.
Mycoplasmal arthritis Treatment: The dose is 1.5 ml/20 kg bodyweight
(equivalent to 15 mg tiamulin hydrogen fumarate/kg body weight) administered
intramuscularly for a period of 3 consecutive days to pigs
showing clinical signs of the disease.

Animals should not receive products containing monensin, narasin or
salinomycin during or for at least seven days before and after treatment with
Denagard 200 Solution for Injection. Severe growth depression or death may
result.

On rare occasions erythema or mild oedema of the skin may occur in pigs
following the use of this product.

For intramuscular use only in pigs.

Revised: April 2025
AN: 04322/2024

i. Special precautions for use in animals
As Denagard 200 Solution for Injection 200 mg/ml is formulated with
sesame oil, it is important to ensure that the syringe used is dry. The
admixture of oil and water may cause the plunger to stick.
ii. Special precautions for the person administering the veterinary
medicinal product to animals
Avoid accidental self-injection.
In case of accidental self-injection, seek medical advice immediately
and show the package leaflet or label to the physician.
Personal protective equipment consisting of gloves should be worn
when handling the veterinary medicinal product.
In case of skin contact with the product, wash immediately with running
water in order to minimise absorption through the skin.
In case of eye contact with the product, wash immediately with running
water and seek medical advice.

Do not store above 25°C. Do not refrigerate.
This product does not contain an antimicrobial preservative. Following
withdrawal of the first dose, use the product within 28 days. Discard unused
material.

Meat and offal: 22 days
5.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.