POM-V Prescription Required

Ultrapen LA 30% Suspension for Injection

Active ingredient: Procaine Benzylpenicillin

Form

Injection

Species

Cattle Pigs

Manufacturer

Norbrook Laboratories Limited

VMD MA No.

02000/4133

What it's used for

Procaine penicillin G is specifically formulated to provide sustained antibacterial activity following a single administration. Ultrapen LA is indicated fo...

Full indications, dosage and side effects ↓

View official SPC (PDF)

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Paying less for Procaine Benzylpenicillin

1

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They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

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The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

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Prescription required

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Clinical information

Ultrapen LA 30% Suspension for Injection — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 26 Mar 2026.

Procaine penicillin G is specifically formulated to provide sustained antibacterial
activity following a single administration.
Ultrapen LA is indicated for use in cattle and pigs in the treatment and control of a
wide range of common systemic, respiratory, urinary and local infections caused by
or associated with organisms sensitive to penicillin, including
pyogenes, , ,
multocida and Streptococcus spp.
Ultrapen LA will therefore be effective in the treatment of infections, caused by
susceptible organisms including:
Erysipelas; navel/joint-ill; respiratory tract infections, including pneumonia and
atrophic rhinitis; meningitis; septicaemia; urogenital tract infections and the control
of secondary bacterial invaders in diseases primarily of viral origin.

Revised: June 2024
AN: 03940/2023

Ultrapen LA is indicated for intramuscular and subcutaneous administration to non-
lactating cattle and for intramuscular administration to pigs and lactating cattle.
The recommended dose rate is 20 mg procaine penicillin/kg bodyweight equivalent
to 1 ml per 15 kg bodyweight. If signs persist at 72 hours repeat the dose.

Ultrapen LA is contraindicated in known cases of hypersensitivity to penicillins.
Do not inject intravenously or by the intrathecal route.
Not to be used on very small herbivores such as guinea pigs, gerbils and
hamsters.

Occasionally in suckling and fattening pigs administration of penicillin may cause a
transient pyrexia, vomiting, shivering, listlessness and incoordination. Additionally
in pregnant sows and gilts a vulval discharge which could be associated with
abortion has been reported.
Although Ultrapen LA is well tolerated, occasionally a slight local reaction of a
transient nature may be observed.
Systemic toxic effects have been observed in young piglets, which are transient but
can be potentially lethal, especially at higher doses.

After absorption, benzylpenicillin poorly penetrates biological membranes (e.g.,
blood-brain barrier) since it is ionised and poorly lipid soluble. Use of the product
for treatment of meningitis or CNS infections due to e.g.,
Listeria monocytogenes
penetrates mammalian cells poorly and hence this product may have little effect in
treating intracellular pathogens e.g., Listeria monocytogenes
Elevated MIC values or bi-modal distribution profiles suggesting acquired
resistance have been reported for the following bacteria:
Glaesserella parasuis, spp. causing MMA/PPDS,
spp. and S. suis in pigs;
Fusobacterium necrophorum as
well as spp.,
and Trueperella pyogenes in cattle.
Use of the veterinary medicinal product may result in a lack of clinical efficacy
when treating infections caused by these bacteria.

i) Special precautions for use in animals
Shake the vial before use. This product does not contain an antimicrobial
preservative. Swab the septum before removing each dose. Use a dry sterile
needle and syringe.
ii) Special precautions to be taken by the person administering the veterinary
medicinal product to animals
Take care to avoid accidental injection. Wash hands after use.
Penicillins and cephalosporins may cause hypersensitivity (allergy) following
injection, inhalation, ingestion or skin contact. Hypersensitivity to penicillins may
lead to cross reactions to cephalosporins and vice versa. Allergic reactions to
these substances may occasionally be serious.
Do not handle this product if you know you are sensitised, or if you have been
advised not to work with such preparations.

Revised: June 2024
AN: 03940/2023
Handle this product with great care to avoid exposure, taking all recommended
precautions.
If you develop symptoms following exposure such as a skin rash, you should seek
medical advice and show the doctor this warning. Swelling of the face, lips or eyes
or difficulty with breathing are more serious symptoms and require urgent medical
attention.

It is inadvisable to use other antibiotics concurrently

Do not store above 25ºC. Protect from light.
Following the withdrawal of the first dose, the product should be used within 28
days. Discard unused material.

Subcutaneous Administration
Animals must not be slaughtered for human consumption during treatment.
Cattle may be slaughtered for human consumption only after 13 days from the last
treatment.

Revised: June 2024
AN: 03940/2023
Intramuscular Administration
Animals must not be slaughtered for human consumption during treatment.
Cattle may be slaughtered for human consumption only after 23 days from the last
treatment.
Pigs may be slaughtered for human consumption only after 10 days from the last
treatment.
Milk for human consumption must not be taken during treatment.
Milk for human consumption may only be taken from treated cows after 132 hours
from the last treatment.
5.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.