POM-V Prescription Required

Multishield DC Intramammary Suspension for Cattle

Active ingredients: Neomycin Sulphate, Penethamate Hydriodide, micronised, Procaine Benzylpenicillin

Form

Intramammary

Species

Cattle

Manufacturer

Bimeda Animal Health Limited

VMD MA No.

50146/4005

What it's used for

Indicated in the treatment of acute and subacute bovine mastitis in milking cows, accompanied by pain and inflammation caused by bacterial infection sensit...

Full indications, dosage and side effects ↓

View official SPC (PDF)

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Prescription required

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Clinical information

Multishield DC Intramammary Suspension for Cattle — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

Indicated in the treatment of acute and subacute bovine mastitis in milking
cows, accompanied by pain and inflammation caused by bacterial infection
sensitive to penicillin, streptomycin and neomycin therapy.

Dose: 100 mg of neomycin sulphate, 100 mg of Penethamate Hydriodide and 400 mg of
Procaine Benzylpenicillin into each quarter. The contents of one syringe should be
infused into each quarter via the teat canal immediately after the final milking of a
lactation.
Before instillation, the udder should be milked out completely.
The teat and its orifice should be thoroughly cleaned and disinfected with a cleaning
towel. Care should be taken to avoid contamination of the injector nozzle.
Gently insert the content of one syringe into each quarter. Disperse the veterinary
medicinal product by gentle massage of the teat and udder. The syringe must only be
used once.

Do not use in lactating cows.
Do not use in cases of hypersensitivity to the active substances, β-lactam antibiotics,
cephalosporin antibiotics, neomycin or other aminoglycoside antibiotics or to any of the
excipients.
Do not use in cows with clinical mastitis.

Target species: Cattle
Very rare
(<1 animal / 10,000 animals treated,
including isolated reports):
Allergic reactions (allergic skin reactions,
anaphylaxis)
Hypersensitivity
AN: 01972/2024 & 01974/2024
May occasionally be serious. If adverse reactions occur, the current treatment should
be withdrawn and symptomatic treatment should be initiated.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or its local representative or the national
competent authority via the national reporting system. See the package leaflet for
respective contact details.

None.
AN: 01972/2024 & 01974/2024

Special precautions for safe use in the target species:
Use of the veterinary medicinal product should be based on susceptibility testing of the
bacteria isolated from the animal. If this is not possible, therapy should be based on local
(regional, farm level) epidemiological information about susceptibility of the target
bacteria.
Official, national and regional antimicrobial policies should be taken into account when
the veterinary medicinal product is used.
The therapeutic efficacy of the veterinary medicinal product is only established against
pathogens that are susceptible to the active substances.
Serious acute mastitis [potentially lethal] due to pathogens like Pseudomonas
aeruginosa, can occur after drying off despite preventive treatment. Good aseptic
practices should be thoroughly respected in order to reduce that risk; cows should be
housed in a hygienic paddock far from the milking parlour and regularly checked several
days after drying off.
Use of the veterinary medicinal product deviating from the instructions given in the SPC
may increase the prevalence of bacteria resistant to benzylpenicillin and may decrease
the effectiveness of treatment with other beta lactam antimicrobials (penicillins and
cephalosporins) due to the potential for cross-resistance.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
Persons administering the veterinary medicinal product should avoid contact with this
preparation as occasionally skin allergy may occur.
Penicillins and cephalosporins may cause sensitisation following injection, inhalation,
ingestion or skin contact. Sensitivity to penicillins may lead to cross sensitivity to
cephalosporins and vice versa. Allergic reactions to these substances may occasionally
be serious.
People with known hypersensitivity to β-lactam antibiotics, cephalosporin antibiotics,
neomycin or other aminoglycoside antibiotics should avoid contact with the veterinary
medicinal product.
If you develop symptoms such as a skin rash following exposure, seek medical advice
and show the package leaflet or the label to the physician. Swelling of the face, lips or
eyes, or difficulty with breathing are more serious symptoms and require urgent medical
attention.
Special precautions for the protection of the environment:
Not applicable.

No data available.

Do not store above 25°C.
Do not refrigerate or freeze.

Meat and Offal: 28 days.
Milk: 96 hours post calving in cows with a dry period of more than 50 days.
50 days plus 96 hours after treatment from cows with a dry period of 50 days or
less.
AN: 01972/2024 & 01974/2024
4.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.