POM-V Prescription Required

Novosol 500 000 IU/g Powder for Use in Drinking Water/Milk for Cattle, Chickens, Pigs, Ducks, Turkeys, Geese, Quail and Partridges

Active ingredient: Neomycin Sulphate

Form

Powder

Species

Cattle Chicken Duck Goose Partridge Pigs Quail Turkeys

Manufacturer

Huvepharma NV

VMD MA No.

30282/3030

What it's used for

Indicated in the treatment of acute and subacute bovine mastitis in milking cows, accompanied by pain and inflammation caused by bacterial infection sensit...

Full indications, dosage and side effects ↓

View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Neomycin Sulphate

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Your prescription rights → VMD register of retailers →

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Novosol 500 000 IU/g Powder for Use in Drinking Water/Milk for Cattle, Chickens, Pigs, Ducks, Turkeys, Geese, Quail and Partridges — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

Indicated in the treatment of acute and subacute bovine mastitis in milking
cows, accompanied by pain and inflammation caused by bacterial infection
sensitive to penicillin, streptomycin and neomycin therapy.

25 000 IU of neomycin per kg bodyweight per day for 3 to 4 consecutive days,
corresponding to 50 mg of veterinary medicinal product per kg bodyweight per day
(i.e. 5 g of veterinary medicinal product per 100 kg bodyweight per day), for 3 to 4
days.
To ensure a correct dosage body weight should be determined as accurately as
possible.
The intake of medicated water or medicated milk replacer depends on the clinical
condition of the animals. In order to obtain the correct dosage, the concentration of
neomycin has to be adjusted accordingly.
The use of suitably calibrated measuring equipment is recommended.
Based on the recommended dose and the number and weight of animals to be
treated, the exact daily concentration of the veterinary medicinal product should be
calculated according to the following formula:
mg veterinary medicinal
product / kg bodyweight
dayX
average body weight
(kg) of animals to be
treated
average daily water/milk replacer intake (L/animal)= mg of veterinary
medicinal product per
litre of drinking
water/milk replacer
The maximum solubility of the veterinary medicinal product is 255 000 IU of
neomycin/mL (510 g of veterinary medicinal product/L) of water.
The veterinary medicinal product should be incorporated in the milk replacer having a
temperature between 21 and 30°C. To achieve the dissolution of the veterinary
medicinal product in milk replacer, a vigorous stirring for 10 minutes should be
applied.
For the administration of the veterinary medicinal product commercially available
dosing pumps can be used.

Do not use in cases of hypersensitivity to the active substance, to aminoglycosides or
to any of the excipients.
Do not use in cases of intestinal obstruction.

Cattle (pre-ruminant), pigs (weaned and fattening pigs), chickens (including laying
hens), ducks, turkeys (including turkey hens), geese, quail and partridges:
None known.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or its local representative or the national
competent authority via the national reporting system. See the package leaflet for
respective contact details.

Cross-resistance has been shown between neomycin and different aminoglycoside
antibiotics in Escherichia coli. Use of the veterinary medicinal product/neomycin
should be carefully considered when susceptibility testing has shown resistance to
aminoglycoside antibiotics because its effectiveness may be reduced.

Special precautions for safe use in the target species:
Powder for oral solution that is to be dissolved in water and cannot be used as it is.
Special care should be taken when considering administration of the veterinary
medicinal product to the newborn calf due to the known higher gastrointestinal
absorption of neomycin in neonates. This higher absorption could lead to an
increased risk of oto- and nephrotoxicity. The use of the veterinary medicinal product
in neonates should be based on the benefit-risk determination from the attending
veterinarian.
Use of the veterinary medicinal product should be based on identification and
susceptibility testing of the target pathogen(s). If this is not possible, therapy should
be based on epidemiological information and knowledge of susceptibility of the target
pathogens at farm level, or at local/regional level.
Use of the product should be in accordance with official, national and regional
antimicrobial policies.
An antibiotic with a lower risk of antimicrobial resistance selection (lower AMEG
category) should be used for first line treatment where susceptibility testing suggests
the likely efficacy of this approach.
Co-selection for other classes of antimicrobials is common (see section 4.2 for further
details).
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
Aminoglycosides may cause hypersensitivity (allergy) following ingestion, inhalation,
or skin contact.
People with known hypersensitivity to neomycin or other aminoglycosides should
avoid contact with the veterinary medicinal product.
Aminoglycosides may be harmful following ingestion, eye or skin contact and
inhalation.
Handle this veterinary medicinal product with great care to avoid dermal exposure,
including hand to mouth contact. Avoid inhalation of dust.
Wear personal protective equipment consisting of appropriate protective
gloves, glasses and disposable half-mask respirator conforming to European
Standard EN149 or a non-disposable respirator to European Standard EN140 with a
filter to EN143 when handling the veterinary medicinal product.
Wash hands after use.
In the event of eye or skin contact, rinse the affected area with large amounts of
clean water.
In case of accidental ingestion, immediately rinse the mouth with water and seek
medical advice.
If you develop symptoms following exposure such as a skin rash, you should seek
medical advice immediately and show the package leaflet or the label to the
physician.
Swelling of the face, lips or eyes or difficulty with breathing are more serious
symptoms and require urgent medical attention.
Special precautions for the protection of the environment:
Not applicable.

General anaesthetics and muscle relaxing products increase the neuro-blocking
effect of aminoglycosides. This may cause paralysis and apnoea.
Special care should be taken when using concurrently with diuretics and potentially
oto- or nephrotoxic substances.

This veterinary medicinal product does not require any special storage conditions.

Cattle (calves):
Meat and offal: 14 days.
Pigs (weaned piglets and pigs for fattening):
Meat and offal: 3 days.
Chickens, ducks, turkeys, geese, quail and partridge:
Meat and offal: 14 days.
Eggs: zero days.
4.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.