POM-V Prescription Required

Tylucyl 200 mg/ml Solution for Injection for Cattle and Pigs

Active ingredient: Tylosin

Form

Injection

Species

Cattle Pigs

Manufacturer

Vetoquinol UK Ltd

VMD MA No.

08007/5052

What it's used for

Cattle (adult): Respiratory infections, metritis caused by Gram-positive microorganisms, mastitis caused by i.e. panaritium or foot root. Calves: Respirato...

Full indications, dosage and side effects ↓

View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Tylosin

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Your prescription rights → VMD register of retailers →

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Tylucyl 200 mg/ml Solution for Injection for Cattle and Pigs — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

Cattle (adult):
Respiratory infections, metritis caused by Gram-positive microorganisms, mastitis
caused by
i.e. panaritium or foot root.
Calves:
Respiratory infections and necrobacillosis.
Pigs (more than 25 kg):
-Enzootic pneumonia, haemorrhagic enteritis, erysipelas and metritis.
-Arthritis caused by
For information regarding swine dysentery see section 3.5.

Cattle:
5 mg to 10 mg of tylosin per kg bodyweight per day during 3 days, i.e 2.5 to 5 ml of
solution per 100 kg bodyweight.
Maximum injection volume per injection site should not exceed 15 ml.
Pigs (more than 25 kg):
5 mg to 10 mg of tylosin per kg bodyweight per day during 3 days, i.e 2.5 to 5 ml of
solution per 100 kg bodyweight.
In pigs do not administer more than 5 ml per injection site.
To ensure a correct dosage, body weight should be determined as accurately as
possible..
The closures should not be broached more than 15 times. In order to prevent
excessive broaching of the stopper, a suitable multiple dosing device should be used.

Do not use in horses.
Intramuscular injection can be fatal in chickens and turkeys.
Do not use in cases of hypersensitivity to tylosin, other macrolides or to any of the
excipients.

Pigs:
Uncommon (1 to 10 animals / 1000
animals treated):
Hypersensitivity reactionVery rare
(<1 animal / 10000 animals treated,
including isolated reports):
Injection site swelling, injection site
inflammation
Erythema, pruritus
Anal prolapse
Anaphylactic shock, rectal oedema
Death
Undetermined frequency
(cannot be estimated from the available
data)
Injection site reaction
1
Partial anal protrusion (« rosebudding »)
Blemishes may persist for up to 21 days after administration
Cattle:
Uncommon (1 to 10 animals / 1000
animals treated):
Hypersensitivity reactionVery rare
(<1 animal / 10000 animals treated,
including isolated reports):
Injection site swelling, injection site
inflammation
Swollen vulva
Anaphylactic shock
Death
Undetermined frequency
(cannot be estimated from the available
data)
Injection site reaction
1
Blemishes may persist for up to 21 days after administration
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorization holder or the national competent authority via the
national reporting system.
See the package leaflet for respective contact details.

None.

Special precautions for safe use in the target species:
Use of the product should be based on identification and susceptibility testing of the
target pathogens. If it is not possible, therapy should be based on epidemiological
information and knowledge of susceptibility of the target bacteria at farm level, or at
local/regional level.
Use of the product should be in accordance with official, national and regional
antimicrobial policies.
Use of the product deviating from the instructions given in the SPC may increase
the prevalence of bacteria resistant to tylosin and may decrease the effectiveness of
treatment with other macrolide antibiotics due to the potential for cross resistance.
A high rate of in vitro resistance has been demonstrated in European strains of
Brachyspira hyodysenteriae
efficacious against swine dysentery.
The efficacy data do not support the use of tylosin for the treatment of bovine
mastitis caused by
concern to animal and human health, potentially delaying a correct diagnosis,
enabling the spread of the pathogen to other cows, impeding efficient/prudent
control measures and increasing the risk for the development of antimicrobial
resistance.
Where repeat injections are to be administered, use different sites for each injection.
Special precautions to be taken by the person administering the veterinary
medicinal product to animals:
Care should be taken to avoid accidental self-injection.
In case of accidental self-injection, seek medical advice immediately and show the
package leaflet or the label to the physician.
In the event of accidental skin contact, wash thoroughly with soap and water. In
case of accidental eye contact, flush the eyes with plenty of clean, running water.
Wash hands after use.
Tylosin may induce irritation. Macrolides, such as tylosin, may also cause
hypersensitivity (allergy) following injection, inhalation, ingestion or contact with
skin or eye. Hypersensitivity to tylosin may lead to cross reactions to other
macrolides and vice versa. Allergic reactions to these substances may occasionally
be serious and therefore direct contact should be avoided.
Do not handle the product if you are allergic to ingredients in the product.
If you develop symptoms following exposure, such as skin rash, you should seek
medical advice and show the physician this warning. Swelling of the face, lips and
eyes or difficulty in breathing are more serious symptoms and require urgent
medical attention.
Special precautions for the protection of the environment:
Tylosin is persistent in some soils.

None known.

Do not store above 25°C.
Store in the original package.
Do not freeze.
Keep the vial in the outer carton in order to protect from light.

Cattle:
Meat and offal: 28 days
Milk: 108 hours
Pigs:
Meat and offal: 16 days

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.