POM-V Prescription Required

Bilovet 200 mg/ml Solution for Injection for Cattle and Pigs

Active ingredient: Tylosin

Form

Injection

Species

Cattle Pigs

Manufacturer

Bimeda Animal Health Limited

VMD MA No.

50146/4016

What it's used for

Cattle (adult): - Treatment of respiratory infections, metritis caused by Gram-positive micro- organisms, mastitis caused by Streptococcus spp., Staphyloco...

Full indications, dosage and side effects ↓

View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Tylosin

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Your prescription rights → VMD register of retailers →

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Bilovet 200 mg/ml Solution for Injection for Cattle and Pigs — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

Cattle (adult):
- Treatment of respiratory infections, metritis caused by Gram-positive micro-
organisms, mastitis caused by Streptococcus spp., Staphylococcus spp. and
interdigital necrobacillosis, caused by Fusobacterium necrophorum , i.e. panaritum or
foot rot.

Revised March 2025
AN: 01886/2024 & 01887/2024
Calves:
- Treatment of respiratory infections and necrobacillosis (calf diphtheria cause by
Fusobacterium necrophorum).
Pigs:
- Treatment of enzootic pneumonia caused by Mycoplasma hyopneumoniae,,
haemorrhagic enteritis, (Porcine proliferative haemorrhagic enteropathy due to
Lawsonia intracellularis) erysipelas caused by
metritis.
- Treatment of arthritis caused by Mycoplasma and Staphylococcus spp.

injection per 100 kg bodyweight). Maximum injection volume per injection site should
not exceed 15 ml.
Pigs: 5 10 mg tylosin/kg bodyweight per day for 3 days (2.5 to 5 ml solution for
injection per 100 kg bodyweight). Maximum injection volume per injection site should
not exceed 5 ml.
To ensure a correct dosage, body weight should be determined as accurately as
possible
to avoid underdosing.
The closure should not be pierced more than 30 times.

Do not use in chickens or turkeys.
Do not use in horses or other equines in which injection of tylosin may be fatal.
Do not use in case of hypersensitivity to the active substance, other macrolides or
any of the excipients.

Cattle:
Very rare
(<1 animal / 10,000 animals treated,
including isolated reports):
Injection site swelling, injection site
inflammation Swollen vulva
Anaphylactic shock
Death
Undetermined frequency
(cannot be estimated from the available
data):
Injection site reaction
1
Blemishes, can persist for up to 21 days following administration.
Pigs:
Very rare
(<1 animal / 10,000 animals treated,
including isolated reports)
Injection site swelling, injection site
inflammation
Rectal oedema
, anaphylactic shock,
Anal prolapse (partial)
,
Erythema, pruritus,
Death

Revised March 2025
AN: 01886/2024 & 01887/2024
Undetermined frequency
(cannot be estimated from the available
data):
Injection site reaction
1
Of the mucosa
(‘rosebudding’)
Blemishes, can persist for up to 21 days following administration.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or its local representative or the national
competent authority via the national reporting system. See the package leaflet for
respective contact details.

None.

Special precautions for safe use in the target species:
Use of the veterinary medicinal product should be based on susceptibility testing of
the bacteria isolated from the animal. If this is not possible, therapy should be based
on local epidemiological information about susceptibility of the target bacteria.
For administration by the intramuscular route only.
Use different injection sites for repeat injections.
Use of the veterinary medicinal product deviating from the instructions given in the
SPC may increase the prevalence of bacteria resistant to the tylosin and may
decrease the effectiveness of treatment with other macrolide antibiotics, due to the
potential for cross resistance.
The efficacy data do not support the use of tylosin for the treatment of bovine mastitis
caused by spp.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
Care should be taken to avoid accidental self-injection.

Revised March 2025
AN: 01886/2024 & 01887/2024
In case of accidental self-injection, seek medical advice immediately and show the
package leaflet or the label to the physician
In the event of accidental skin contact, wash thoroughly with soap and water. In case
of accidental eye contact, flush the eyes with plenty of clean, running water.
Wash hands after use.
Tylosin may induce irritation. Macrolides, such as tylosin, may also cause
hypersensitivity (allergy) following injection, inhalation, ingestion or contact with skin
or eye. Hypersensitivity to tylosin may lead to cross reactions to other macrolides
and vice versa. Allergic reactions to these substances may occasionally be serious
and therefore direct contact should be avoided.
Do not handle the veterinary medicinal product if you are allergic to ingredients in the
veterinary medicinal product.
If you develop symptoms following exposure, such as skin rash, you should seek
medical advice and show the physician this warning. Swelling of the face, lips and
eyes or difficulty in breathing are more serious symptoms and require urgent medical
attention.
Special precautions for the protection of the environment:
Not applicable.

Lincosamide and aminoglycoside antibiotics can antagonise the action of tylosin.

Do not store above 25°C.
Protect from light.

Pigs: Meat and offal; 16 days
Cattle: Meat and offal; 28 days
Milk;120 hours.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.