Pharmasin 1g/g Granules for Use in Drinking Water for Pigs, Chickens, Turkeys and Calves
Active ingredient: Tylosin
Form
Powder
Species
Manufacturer
Huvepharma NV
VMD MA No.
30282/5006
What it's used for
Calves: Treatment and metaphylaxis of pneumonia caused by Mycoplasma spp when the disease has been established in the herd. Pigs: Treatment and metaphylaxi...
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Paying less for Tylosin
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Ask your vet for a written prescription
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Fill it at a registered online retailer
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Prescription required
Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.
Pharmasin 1g/g Granules for Use in Drinking Water for Pigs, Chickens, Turkeys and Calves — SPC Details
Source: VMD Summary of Product Characteristics (SPC). Last updated 26 Mar 2026.
when the disease has been established in the herd.
Pigs: Treatment and metaphylaxis of enzootic pneumonia caused by Mycoplasma
hyopneumoniae and Mycoplasma hyorhinis when the disease has been established
in the herd.
Treatment and metaphylaxis of Porcine Intestinal Adenomatosis (Ileitis) associated
with Lawsonia intracellularis
Chickens: Treatment and metaphylaxis of chronic respiratory diseases (CRD) caused
by Mycoplasma gallisepticum and Mycoplasma synoviae when the disease has been
established in the flock.
Treatment and metaphylaxis of necrotic enteritis caused by Clostridium perfringens
when the disease has been established in the flock.
Turkeys: Treatment and metaphylaxis of infectious sinusitis caused by Mycoplasma
gallisepticum. when the disease has been established in the flock.
Revised: January 2025
AN: 01569/2024
Do not use in cases of known resistance to tylosin or cross-resistance to other
macrolides (MLS-resistance).
Do not use in animals vaccinated with tylosin-sensitive vaccines either at the same
time or within 1 week previously.
Do not use in animals with hepatic disorders.
Do not use in horses because of danger for inflammation of the caecum.
Undetermined frequency (cannot be
estimated from the available data)
Diarrhoea*, pruritus*, reddening of the
skin*, swollen vulva*, rectal oedema* and
rectal prolapse*
* all transient and appear 48-72 hours after start of the treatment
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or the national competent authority via the
national reporting system. See section 16 of the package leaflet for respective
contact details.
bacteriological sampling and susceptibility testing are recommended.
Under-dosing and/or treating for an insufficient length of time are considered to
promote the development of resistance in bacteria and should be avoided.
Special precautions for use in animals
Animals with acute infections may have a reduced water and feed consumption and
should be treated with a suitable injectable veterinary medicinal product first.
Do not leave or dispose of water containing tylosin tartrate where it may be
accessible to either animals not under treatment or wildlife.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
Tylosin may induce irritation. Macrolides, such as tylosin, may also cause
hypersensitivity (allergy) following injection, inhalation, ingestion or contact with skin
or eye. Hypersensitivity to tylosin may lead to cross reactions to other macrolides
and vice versa. Allergic reactions to these substances may occasionally be serious
and therefore direct contact should be avoided.
To avoid exposure during preparation of the medicated drinking water, wear overalls,
safety glasses, impervious gloves and wear either a disposable half mask respirator
conforming to European Standard EN149 or a non-disposable respirator to European
Standard EN140 with a filter to EN143.
Wash hands after use.
In the event of accidental skin contact, wash thoroughly with soap and water. In case
of accidental eye contact, flush the eyes with plenty of clean, running water.
Do not handle the product if you are allergic to ingredients in the product.
If you develop symptoms following exposure, such as skin rash, you should seek
medical advice and show the physician this warning. Swelling of the face, lips and
eyes or difficulty in breathing are more serious symptoms and require urgent medical
attention.
Revised: January 2025
AN: 01569/2024
Special precautions for the protection of the environment:
Not applicable.
Other precautions:
Not applicable.
Keep the container tightly closed.
For the preparation of the medicated water/milk/milk-replacer the body weight of the
animals to be treated and their actual daily water/milk/milk-replacer consumption
should be taken into due account. Consumption may vary depending on factors like
age, state of health, breed, husbandry system. To provide the required amount of
active substance in mg per litre drinking water/milk/milk-replacer the following
calculation should be made:
…… mg tylosin perAverage bodyweight (kg)kg bodyweight per dayxof the animals to be
treated
=…...mg tylosin /Average amount of drinking water or milk / animal (l)l of drinking water
Sufficient access to the system of water supply should be available for the animals to
be treated to ensure adequate water consumption. No other source of drinking water
should be available during the medication period.
Should there be no clear response to treatment within 3 days the treatment approach
should be reconsidered. After the end of the medication period the water supply
system should be cleaned appropriately to avoid intake of sub-therapeutic amounts
of the active substance which might support development of resistance.
Medicated water, milk or milk replacer should be replaced every 24 hours.
If individual animals show signs of a serious infection such as a reduced water or
feed intake, then they should be treated individually, such as by injection.
4.10 Overdose (symptoms, emergency procedures, antidotes), if necessary
There is no evidence of tylosin toxicity in rats, at dose rates of up to 1000 mg/kg by
the oral route.
Revised: January 2025
AN: 01569/2024
There is no evidence of tylosin toxicity in chickens, turkeys, pigs or calves when
administered orally at up to three times the recommended dose.
4.11 Withdrawal periods
Calves (meat and offal): 12 days
Pigs (meat and offal): 1 day
Turkeys (meat and offal): 2 days
Turkey (eggs): Zero days
Chickens (meat and offal): 1 day
Chicken (eggs): Zero days
5.
This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.
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Other Products Containing Tylosin
These products share the same active ingredient and may be suitable alternatives. Always consult your vet.
Bilovet 200 mg/ml Solution for Injection for Cattle and Pigs
POM-VBimeda Animal Health Limited
Pharmasin 100000 IU/g Premix for Medicated Feeding Stuff for Pigs, Broilers and Pullets
POM-VHuvepharma N.V.
Pharmasin 100000 IU/g Premix for Medicated Feeding Stuff for Pigs, Broilers and Pullets
POM-VHuvepharma N.V.
Pharmasin 1g/g Granules for Use in Drinking Water for Pigs, Chickens, Turkeys and Calves
POM-VHuvepharma NV
Pharmasin 200 mg/ml Solution for Injection for Cattle and Pigs
POM-VHuvepharma N.V.
Pharmasin 20000 IU/g Oral Granules for Pigs
POM-VHuvepharma N.V.
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