Pharmasin 1g/g Granules for Use in Drinking Water for Pigs, Chickens, Turkeys and Calves

In cattle (calves) the veterinary medicinal product can also be administered through
milk or milk replacer.
1.1 gram of the veterinary medicinal product corresponds to 1 gram of tylosin. The
dosages are as follows:
Cattle (calves):
10 – 20 mg tylosin per kg BW (corresponding to 11 – 22 mg of the veterinary
medicinal product per kg BW), twice daily (corresponding to a daily dose of 20 – 40
mg tylosin per kg BW), for 7 – 14 days.
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Turkeys:
75 – 100 mg tylosin per kg BW per day (corresponding to 82.5 – 110 mg of the
veterinary medicinal product per kg BW) for 3 – 5 days.
Chickens:
For the treatment of chronic respiratory disease:
75 – 100 mg tylosin per kg BW per day (corresponding to 82.5 – 110 mg of the
veterinary medicinal product per kg BW) for 3 – 5 days.
For the treatment of necrotic enteritis:
20 mg tylosin per kg BW per day (corresponding to 22 mg of the veterinary medicinal
product) for 3 days.
Pigs:
For the treatment of enzootic pneumonia:
20 mg tylosin per kg BW per day (corresponding to 22 mg of the veterinary medicinal
product per kg BW) for 10 days.
For the treatment of ileitis or PIA:
5 – 10 mg tylosin per kg BW per day (corresponding to 5.5 – 11 mg of the veterinary
medicinal product per kg BW) for 7 days.
To ensure a correct dosage, body weight should be determined as accurately as
possible. The intake of medicated water/milk/milk replacer depends on the clinical
condition of the animals. In order to obtain the correct dosage, the concentration of
tylosin may need to be adjusted accordingly. Based on the recommended dose and
the number and weight of animals to be treated, the exact daily concentration of the
veterinary medicinal product should be calculated according to the following formula:
…… mg veterinary
medicinal product per
kg body weight
per day

x
Average bodyweight (kg)
of the animals to be
treated
=
……mg veterinary
medicinal product /
Average amount of drinking water or milk / animal (l)l of drinking water
Sufficient access to the system of water supply should be available for the animals to
be treated to ensure adequate water consumption. No other source of drinking water
should be available during the medication period.
Should there be no clear response to treatment within 3 days the treatment approach
should be reconsidered. After the end of the medication period the water supply
system should be cleaned appropriately to avoid intake of sub-therapeutic amounts
of the active substance which might support development of resistance.
Medicated water, milk or milk replacer should be replaced every 24 hours.
If individual animals show signs of a serious infection such as a reduced water or
feed intake, then they should be treated individually, such as by injection.