POM-V Prescription Required

Pharmasin 200 mg/ml Solution for Injection for Cattle and Pigs

Active ingredient: Tylosin

Form

Injection

Species

Cattle Pigs

Manufacturer

Huvepharma N.V.

VMD MA No.

30282/4028

What it's used for

Cattle (adult): - Treatment of respiratory infections, metritis caused by Gram-positive micro- organisms, mastitis caused by Streptococcus spp., Staphyloco...

Full indications, dosage and side effects ↓

View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Tylosin

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Your prescription rights → VMD register of retailers →

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Pharmasin 200 mg/ml Solution for Injection for Cattle and Pigs — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

Cattle (adult):
- Treatment of respiratory infections, metritis caused by Gram-positive micro-
organisms, mastitis caused by Streptococcus spp., Staphylococcus
interdigital necrobacillosis caused by Fusobacterium necrophorum
foot rot
Cattle (calves):
- Treatment of respiratory infections and necrobacillosis (calf diphtheria caused by
Fusobacterium necrophorum)
AN: 03841/2024 & 03843/2024
Pigs:
- Treatment of enzootic pneumonia caused by Mycoplasma hyopneumoniae
haemorrhagic enteritis (Porcine proliferative haemorrhagic enteropathy due to
Lawsonia intracellularisErysipelothrix rhusiopathiae and
metritis.
- Treatment of arthritis caused by Mycoplasma and Staphylococcus

injection per 100 kg bodyweight). Maximum injection volume per injection site should
not exceed 15 ml.
Pigs: 5-10 mg tylosin/kg bodyweight per day for 3 days (2.5 to 5 ml solution for
injection per 100 kg bodyweight). In pigs do not administer more than 5 ml per
injection site.
The closures should not be broached more than 15 times. In order to prevent
excessive broaching of the stopper, a suitable multiple dosing device should be used.
To ensure a correct dosage, body weight should be determined as accurately as
possible.

Do not use in chickens or turkeys in which intramuscular injection may be fatal.
Do not use in horses or other equines in which injection of tylosin may be fatal.
Do not use in cases of hypersensitivity to the active substance, other macrolides or to
any of the excipients.

Cattle:
Injection site reactionSwollen vulvaAnaphylactic shockVery rare
(<1 animal / 10,000 animals
treated, including isolated
reports):
DeathUndetermined frequency
(cannot be estimated from the
available data):
Blemishes at the injection site
1
can persist for up to 21 days following administration.
Pigs:
Injection site reactionRectal oedema
Anaphylactic shock
Erythema
Pruritus
Rectal prolapse (partial)1Very rare
(<1 animal / 10,000 animals
treated, including isolated
reports):
DeathUndetermined frequency
(cannot be estimated from the
available data):
Blemishes at the injection site2
‘Rosebudding’
can persist for up to 21 days following administration.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or the national competent authority via the
national reporting system. See the package leaflet for respective contact details.

None.

Special precautions for safe use in the target species:
Use of the veterinary medicinal product should be based on susceptibility testing of
the bacteria isolated from the animal. If this is not possible, therapy should be based
on local (regional, farm level) epidemiological information about susceptibility of the
target bacteria.
The efficacy data do not support the use of tylosin for the treatment of bovine mastitis
caused by Mycoplasma
Use of the veterinary medicinal product deviating from the instructions given in the
SPC may increase the prevalence of bacteria resistant to tylosin and may decrease
the effectiveness of treatment with other macrolide antibiotics due to the potential for
cross resistance.
For administration by the intramuscular route only.
Use different injection sites for repeated injections.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
Macrolides, such as tylosin may cause hypersensitivity (allergy) following injection,
inhalation, ingestion or contact with skin or eye. Hypersensitivity to tylosin may lead
to cross reactions to other macrolides and vice versa. Allergic reactions to these
substances may occasionally be serious. People with known hypersensitivity to
tylosin should avoid contact with the veterinary medicinal product. If you develop
symptoms following exposure, such as skin rash, you should seek medical advice
and show the physician this warning. Swelling of the face, lips and eyes or difficulty
in breathing are more serious symptoms and require urgent medical attention. Care
should be taken to avoid accidental self-injection. In case of accidental self-injection,
seek medical advice immediately and show the package leaflet or the label to the
physician.
AN: 03841/2024 & 03843/2024
Tylosin may induce irritation. Avoid skin and/or eye contact. In the event of
accidental skin contact, wash thoroughly with soap and water. In case of accidental
eye contact, flush the eyes with plenty of clean, running water.
Wash hands after use.
Special precautions for the protection of the environment:
Not applicable.

Lincosamide and aminoglycoside antibiotics can antagonise the action of tylosin.

Protect from light.
Store in the original container.
Do not store above 25°C.
Do not freeze.
AN: 03841/2024 & 03843/2024

Pigs: Meat and offal – 16 days
Cattle: Meat and offal – 28 days
Milk – 108 hours.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.