POM-V Prescription Required

Tylovectin 200 Solution for Injection for Cattle, Goats and Pigs

Active ingredient: Tylosin

Form

Injection

Species

Cattle Goats Pigs

Manufacturer

Huvepharma N.V.

VMD MA No.

30282/3013

What it's used for

Cattle : Respiratory infections, metritis caused by Gram-positive microorganisms, mastitis caused by , and interdigital necrobacillosis, i.e. panaritium or...

Full indications, dosage and side effects ↓

View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Tylosin

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Your prescription rights → VMD register of retailers →

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Tylovectin 200 Solution for Injection for Cattle, Goats and Pigs — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

Cattle :
Respiratory infections, metritis caused by Gram-positive microorganisms, mastitis
caused by , and interdigital necrobacillosis,
i.e. panaritium or foot rot.
Cattle (calves):
Respiratory infections and necrobacillosis.

Revised December 2023
Pigs:
Enzootic pneumonia, haemorrhagic enteritis, erysipelas and metritis.
Arthritis caused by . and
For information regarding swine dysentery see section 3.5.
Goats:
Respiratory infections, metritis caused by Gram-positive microorganisms, mastitis
caused by Gram-positive microorganisms or Mycoplasma spp.

5 ml solution for injection per 100 kg bodyweight).
Maximum injection volume per injection site should not exceed 15 ml in cattle.
Goats: 10 000 IU tylosin/kg bodyweight per day for 3 days (5 ml solution for injection
per 100 kg bodyweight).
Pigs: 5 000 IU to 10 000 IU of tylosin per kg bodyweight per day during 3 days,
2.5 to 5 ml of solution per 100 kg bodyweight.
In pigs do not administer more than 5 ml per injection site.
Where repeat injections are to be administered, use different sites for each injection.
To ensure a correct dosage, body weight should be determined as accurately as
possible.
The closures should not be broached more than 15 times. In order to prevent
excessive broaching of the stopper, a suitable multiple dosing device should be used.

Do not use in chickens, turkeys and horses.
Do not use in cases of hypersensitivity to the active substance, other macrolides or
any of the excipients.

Cattle:
Very rare
(<1 animal / 10,000- animals
treated, including isolated reports):
- Injection site swelling, injection site
inflammation
- Swollen vulva
- Anaphylactic shock
- Death
Undetermined frequency (cannot be
estimated from available data)
- Hypersensitivity reaction
- Injection site lesion
1
Can persist for up to 21 days following administration
Pigs:
Very rare
(<1 animal / 10,000 animals treated,
including isolated reports):
- Injection site swelling, Injection site
inflammation
- Anaphylactic shock
- Rectal oedema
- Erythema
- Pruritus
- Rectal prolapse (partial)
- Death
Undetermined frequency (cannot be
estimated from available data)
- Hypersensitivity reaction
- Injection site lesion
2
Can persist for up to 21 days following administration
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or its local representative or the national
competent authority via the national reporting system. See the package leaflet for
respective contact details.

Revised December 2023

None.

Special precautions for safe use in the target species:
Due to likely variability (time, geographical) in susceptibility of bacteria to tylosin,
bacteriological sampling and susceptibility testing are recommended. Official,
national and regional antimicrobial policies should be taken into account when the
veterinary medicinal product is used
Use of the veterinary medicinal product deviating from the instructions given in the
SPC may increase the prevalence of bacteria resistant to tylosin and may decrease
the effectiveness of treatment with other macrolide antibiotics due to the potential for
cross resistance.
A high rate of in vitro
Brachyspira hyodysenteriae implying that the veterinary medicinal product will not be
sufficiently efficacious against swine dysentery.
The efficacy data do not support the use of tylosin for the treatment of bovine mastitis
caused by spp.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
Care should be taken to avoid accidental self-injection.
In case of accidental self-injection, seek medical advice immediately and show the
package leaflet or the label to the physician.
In the event of accidental skin contact, wash thoroughly with soap and water. In case
of accidental eye contact, flush the eyes with plenty of clean, running water.

Revised December 2023
Wash hands after use.
People with known hypersensitivity to tylosin, benzylalcohol or propylene glycol
should avoid contact with the veterinary medicinal product.
Tylosin may induce irritation. Macrolides, such as tylosin, may also cause
hypersensitivity (allergy) following injection, inhalation, ingestion or contact with skin
or eye. Hypersensitivity to tylosin may lead to cross reactions to other macrolides and
vice versa. Allergic reactions to these substances may occasionally be serious and
therefore direct contact should be avoided.
If you develop symptoms following exposure, such as skin rash, you should seek
medical advice and show the physician this warning. Swelling of the face, lips and
eyes or difficulty in breathing are more serious symptoms and require urgent medical
attention.
Special precautions for the protection of the environment
Not applicable.

None known.

Do not store above 25 C.
Do not freeze.
Keep the vial in the outer carton in order to protect from light.

Cattle:
Meat and offal – 28 days

Revised December 2023
Milk – 108 hours
Goat:
Meat and offal – 42 days
Milk – 108 hours
Pigs:
Meat and offal – 16 days

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.