POM-V Prescription Required

Tylan G250 Premix for Medicated Feedingstuff

Active ingredient: Tylosin

Form

Premix

Species

Chickens Pigs

Manufacturer

Elanco GmbH

VMD MA No.

52127/5085

What it's used for

Pigs: For the prevention and control of enzootic pneumonia. For the treatment and control of Lawsonia intracellularis, the organism associated with Porcine...

Full indications, dosage and side effects ↓

View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Tylosin

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Your prescription rights → VMD register of retailers →

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Tylan G250 Premix for Medicated Feedingstuff — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

Pigs:
For the prevention and control of enzootic pneumonia.
For the treatment and control of Lawsonia intracellularis, the organism
associated with Porcine Intestinal Adenomatosis (Ileitis) and Porcine
Haemorrhagic Enteropathy.
Broilers and pullets:
Treatment and prevention of respiratory infections caused by Mycoplasma
gallisepticum and , when the disease has been
diagnosed in the flock.
Treatment and prevention of necrotic enteritis caused by Clostridium
perfringens, when the disease has been diagnosed in the flock.
The presence of the disease in the group or flock must be established
before the product is used.

Revised: April 2025
AN: 04322/2024

Do not use in cases of hypersensitivity to the active substance or to any of
the excipients.
Do not use in animals vaccinated with tylosin-sensitive vaccines either at the
same time or within one week previously.

None known.
Reporting adverse events is important. It allows continuous safety
monitoring of a veterinary medicinal product. Reports should be sent,
preferably via a veterinarian, to either the marketing authorisation holder or
the national competent authority via the national reporting system. See the
package leaflet for respective contact details.

None.

Use of the product should be in accordance with official, national and
regional antimicrobial policies.
Special precautions for use in animals
For incorporation into medicated feedingstuffs only.
To ensure thorough dispersion of the product it should first be mixed with a
small quantity of feed ingredients before incorporation into the final mix.
Use of the product should be based on identification and susceptibility
testing of the target pathogen(s). If this is not possible, therapy should be
based on epidemiological information and knowledge of susceptibility of the
target pathogens at farm level, or at local/regional level.
An antibiotic with a lower risk of antimicrobial resistance selection (lower
AMEG category) should be used for first line treatment where susceptibility
testing suggests the likely efficacy of this approach.
Special precautions to be taken by the person administering the veterinary
medicinal product to animals
Tylosin may induce irritation. Macrolides, such as tylosin, may also cause
hypersensitivity (allergy) following injection, inhalation, ingestion or contact
with skin or eye. Hypersensitivity to tylosin may lead to cross reactions to
other macrolides and vice versa. Allergic reactions to these substances may
occasionally be serious and therefore direct contact should be avoided.
To avoid exposure during preparation of the medicated feed, wear overalls,
safety glasses, impervious gloves and wear either a disposable half mask
respirator conforming to European Standard EN149 or a non-disposable
respirator to European Standard EN140 with a filter to EN143. Wash hands
after use.
In the event of accidental skin contact, wash thoroughly with soap and
water. In case of accidental eye contact, flush the eyes with plenty of clean,
running water.

Revised: April 2025
AN: 04322/2024
Page 3 of 7Do not handle the product if you are allergic to ingredients in the product.
If you develop symptoms following exposure, such as skin rash, you should
seek medical advice and show the package leaflet or the label to the
physician .
Swelling of the face, lips and eyes or difficulty in breathing are more serious
symptoms and require urgent medical attention.
Special precautions for the protection of the environment
Not applicable
Other precautions
Not applicable

interaction
Lincosamides and aminogylcoside antibiotics antagonise the activity of
tylosin.

Bag (i) (3-ply kraft paper sack) Do not store above 25°C. Store in a dry
place.

Revised: April 2025
AN: 04322/2024
Bag (ii) (multiwalled sack). Do not store above 25°C. Store in a dry place.
The product will remain stable in finished feed for three months when stored
below 25°C.

Meat and offal:
Pigs: Zero days.
Broilers and pullets: 1 day
Not authorised for use in birds producing eggs for human consumption.

Revised: April 2025
AN: 04322/2024
5.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.