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Ornicure 150 mg/g, Powder for Use in Drinking Water for Racing Pigeons and Ornamental Birds
Active ingredient: Doxycycline Hyclate
Form
Powder
Species
Ornamental Birds
Pigeon (non-food producing)
Manufacturer
Oropharma n.v
VMD MA No.
13058/4005
What it's used for
Treatment of infections caused by micro-organisms: •Chlamydophila psittaci, Pasteurella multocida, Mycoplasma spp. •
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Clinical information
Ornicure 150 mg/g, Powder for Use in Drinking Water for Racing Pigeons and Ornamental Birds — SPC Details
Source: VMD Summary of Product Characteristics (SPC). Last updated 26 Mar 2026.
Treatment of infections caused by micro-organisms:
•Chlamydophila psittaci,
Pasteurella multocida, Mycoplasma spp.
•
•Chlamydophila psittaci,
Pasteurella multocida, Mycoplasma spp.
•
In drinking water use.
Racing pigeons:
- Treatment of infections due to :
46 mg doxycycline hyclate/day/kg bodyweight for at least 30 days
- Treatment of infections due to other pathogens (Pasteurella multocida,
Mycoplasma spp): 20 mg doxycycline hyclate/day/kg bodyweight for 5 days
The medicated drinking water can also be administered directly into the crop.
Ornamental birds, particularly Psittaciformes (e.g. African grey parrots,
Goffin's cockatoos, cockatiels):
For the treatment of infections due to Chlamydophyla psittaci, the drinking water
should be medicated in:
African grey parrots:
at a dose of 800 mg doxycycline hyclate/day/L drinking water ad libitum for 42 days
or 54 mg doxycycline hyclate/day/kg bodyweight;
Goffin’s cockatoos:
at a dose of 400 mg doxycycline hyclate/day/L drinking water ad libitum for 42 days
or 24 mg doxycycline hyclate/day/kg bodyweight;
Cockatiels:
at a dose of 400 mg doxycycline hyclate/day/L drinking water ad libitum (or 40 mg
doxycycline hyclate/day/kg bodyweight via feeding tube into the crop) for 30 days.
Owing to physiological and pharmacokinetic differences between the wide range of
species for which this product is indicated, the dose rates above are for guidance
only. Depending upon the species of animal and the infection to be treated,
alternative doses may be appropriate using an evidence-based approach. However,
Revised: August 2021
AN: 01342/2020
any change in dosing regimen should be based on a benefit:risk assessment by the
responsible veterinarian, as tolerance at higher doses has not been investigated.
The exact daily amount of the product can be calculated using the following formula
as guidance:
... mg product/kg
bodyweight/day*
mean bodyweight
(kg) of birds to be
treated
Mean daily water uptake (L) per bird
=
... mg product per L drinking
water
* 10 mg doxycycline hyclate/kg bodyweight is equivalent to 67 mg product/kg
bodyweight.
To ensure a correct dosage, the body weight should be determined as accurately as
possible.
The uptake of medicated drinking water depends on the clinical condition of the birds.
To obtain the correct dosage the concentration in the drinking water may have to be
adjusted accordingly.
The medicated drinking water is a clear, colourless to yellow solution.
The maximal solubility of the product in soft/hard water at 20°C is around 390 g/L and
in soft/hard water at 5°C around 190 g/L.
Warning: The solubility of the product depends on the pH-value; in hard alkaline
water the product can precipitate. Water with a hardness of > 19.2°d and a pH-value
of > 8.1 is not suitable for dissolving this product.
The use of suitably calibrated weighing equipment is recommended if parts of the
packs are used. The daily amount is to be added to the drinking water such that all
medication will be consumed in 24 hours. Medicated drinking water should be
replaced every 24 hours.
No other source of drinking water should be available during the medication period.
Racing pigeons should be kept in the pigeon loft during treatment.
The water supply system should be cleaned appropriately after the end of the
medication period to avoid intake of sub-therapeutic amounts of the active
substance.
Racing pigeons:
- Treatment of infections due to :
46 mg doxycycline hyclate/day/kg bodyweight for at least 30 days
- Treatment of infections due to other pathogens (Pasteurella multocida,
Mycoplasma spp): 20 mg doxycycline hyclate/day/kg bodyweight for 5 days
The medicated drinking water can also be administered directly into the crop.
Ornamental birds, particularly Psittaciformes (e.g. African grey parrots,
Goffin's cockatoos, cockatiels):
For the treatment of infections due to Chlamydophyla psittaci, the drinking water
should be medicated in:
African grey parrots:
at a dose of 800 mg doxycycline hyclate/day/L drinking water ad libitum for 42 days
or 54 mg doxycycline hyclate/day/kg bodyweight;
Goffin’s cockatoos:
at a dose of 400 mg doxycycline hyclate/day/L drinking water ad libitum for 42 days
or 24 mg doxycycline hyclate/day/kg bodyweight;
Cockatiels:
at a dose of 400 mg doxycycline hyclate/day/L drinking water ad libitum (or 40 mg
doxycycline hyclate/day/kg bodyweight via feeding tube into the crop) for 30 days.
Owing to physiological and pharmacokinetic differences between the wide range of
species for which this product is indicated, the dose rates above are for guidance
only. Depending upon the species of animal and the infection to be treated,
alternative doses may be appropriate using an evidence-based approach. However,
Revised: August 2021
AN: 01342/2020
any change in dosing regimen should be based on a benefit:risk assessment by the
responsible veterinarian, as tolerance at higher doses has not been investigated.
The exact daily amount of the product can be calculated using the following formula
as guidance:
... mg product/kg
bodyweight/day*
mean bodyweight
(kg) of birds to be
treated
Mean daily water uptake (L) per bird
=
... mg product per L drinking
water
* 10 mg doxycycline hyclate/kg bodyweight is equivalent to 67 mg product/kg
bodyweight.
To ensure a correct dosage, the body weight should be determined as accurately as
possible.
The uptake of medicated drinking water depends on the clinical condition of the birds.
To obtain the correct dosage the concentration in the drinking water may have to be
adjusted accordingly.
The medicated drinking water is a clear, colourless to yellow solution.
The maximal solubility of the product in soft/hard water at 20°C is around 390 g/L and
in soft/hard water at 5°C around 190 g/L.
Warning: The solubility of the product depends on the pH-value; in hard alkaline
water the product can precipitate. Water with a hardness of > 19.2°d and a pH-value
of > 8.1 is not suitable for dissolving this product.
The use of suitably calibrated weighing equipment is recommended if parts of the
packs are used. The daily amount is to be added to the drinking water such that all
medication will be consumed in 24 hours. Medicated drinking water should be
replaced every 24 hours.
No other source of drinking water should be available during the medication period.
Racing pigeons should be kept in the pigeon loft during treatment.
The water supply system should be cleaned appropriately after the end of the
medication period to avoid intake of sub-therapeutic amounts of the active
substance.
Do not use in cases of hypersensitivity to the active substance, to other tetracyclines
or to any of the excipients.
or to any of the excipients.
As for all tetracyclines, on rare occasions allergic reactions and photosensitivity may
occur.
Intestinal flora may be affected if treatment is prolonged (> 10 days), and this may
result in digestive disturbance. If suspected adverse reactions occur, treatment
should be discontinued.
A slight weight loss may occur.
The frequency of adverse reactions is defined using the following convention:
- very common (more than 1 in 10 animals treated displaying adverse reaction(s))
- common (more than 1 but less than 10 animals in 100 animals treated)
- uncommon (more than 1 but less than 10 animals in 1,000 animals treated)
- rare (more than 1 but less than 10 animals in 10,000 animals treated)
- very rare (less than 1 animal in 10,000 animals treated, including isolated reports).
Revised: August 2021
AN: 01342/2020
occur.
Intestinal flora may be affected if treatment is prolonged (> 10 days), and this may
result in digestive disturbance. If suspected adverse reactions occur, treatment
should be discontinued.
A slight weight loss may occur.
The frequency of adverse reactions is defined using the following convention:
- very common (more than 1 in 10 animals treated displaying adverse reaction(s))
- common (more than 1 but less than 10 animals in 100 animals treated)
- uncommon (more than 1 but less than 10 animals in 1,000 animals treated)
- rare (more than 1 but less than 10 animals in 10,000 animals treated)
- very rare (less than 1 animal in 10,000 animals treated, including isolated reports).
Revised: August 2021
AN: 01342/2020
The uptake of medicated drinking water by animals can be altered as a consequence
of illness and should be monitored carefully. In case of insufficient uptake of water, it
is advised to administer doxycycline directly into the crop or to medicate parenterally.
Revised: August 2021
AN: 01342/2020
Medication should be combined with good management practices, e.g. good hygiene
and ventilation and, as far as applicable, appropriate stocking density.
Doxycycline (re)absorption may be reduced when birds are given grit. It is therefore
recommended to suppress grit and mineral additives during the treatment in pigeons
and to limit calcium to a maximum content of 0.7% in pelleted feed in parrots.
Cross-resistance has been shown between doxycycline and others tetracyclines. Use
of the product should be carefully considered when susceptibility testing has shown
resistance to tetracyclines because its effectiveness may be reduced.
Special precautions for use in animals
Due to the likely variability (time, geographical) in the susceptibility of bacteria to
doxycycline, bacteriological sampling and susceptibility testing of micro-organisms
originating from diseased animals are strongly recommended.
Use of the product deviating from the instructions given in the SPC/product literature
may increase the prevalence of bacteria resistant to doxycycline due to the potential
for cross resistance with other tetracyclines and may decrease the effectiveness of
the treatment.
Use of the product should take into account official and local antimicrobial policies.
Avoid administration in oxidized drinking equipment.
See section 4.10 for additional warnings.
Toxic concentrations might also be reached in birds housed in hot, outdoor climates
where water consumption is increased. Birds undergoing treatment should be
monitored for signs of doxycycline toxicosis, including lethargy, inappetance,
inactivity, and passing yellow or green urine. Doxycycline toxicosis caused hepatic
damage and dysfunction that may result in high plasma AST, lactate dehydrogenase,
and bile acids. Doxycycline treatment should be discontinued and general supportive
care started if doxycycline toxicosis is suspected.
The quality of the drinking water may influence the bioavailability of the product. See
Section 4.9.
Revised: August 2021
AN: 01342/2020
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
This product may cause contact dermatitis and/or hypersensitivity reactions if contact
is made with the skin or eyes (powder and solution), or if the powder is inhaled.
People with a possible hypersensitivity to tetracyclines should avoid contact with this
veterinary medicinal product.
Take measures to avoid producing dust or inhalation of dust particles when
incorporating the product into water. Avoid direct contact with skin and eyes when
handling and administering the product.
Wear impermeable gloves (e.g. rubber or latex) and an appropriate dust mask
(disposable half-mask respirator conforming to European Standard EN 149 (FFP2) or
a non-disposable respirator to European Standard EN 140 with a filter to EN 143)
during the preparation and the administration of the solution.
In the event of eye or skin contact, rinse the affected area with large amounts of
clean water and if irritation occurs, seek medical attention.
Wash hands and contaminated skin immediately after handling the product.
If you develop symptoms following exposure such as skin rash, you should seek
medical advice and show this warning to the physician. Swelling of the face, lips or
eyes, or difficulty with breathing are more serious symptoms and require urgent
medical attention.
Do not smoke, eat or drink while handling the product.
In case of accidental ingestion, seek medical attention.
of illness and should be monitored carefully. In case of insufficient uptake of water, it
is advised to administer doxycycline directly into the crop or to medicate parenterally.
Revised: August 2021
AN: 01342/2020
Medication should be combined with good management practices, e.g. good hygiene
and ventilation and, as far as applicable, appropriate stocking density.
Doxycycline (re)absorption may be reduced when birds are given grit. It is therefore
recommended to suppress grit and mineral additives during the treatment in pigeons
and to limit calcium to a maximum content of 0.7% in pelleted feed in parrots.
Cross-resistance has been shown between doxycycline and others tetracyclines. Use
of the product should be carefully considered when susceptibility testing has shown
resistance to tetracyclines because its effectiveness may be reduced.
Special precautions for use in animals
Due to the likely variability (time, geographical) in the susceptibility of bacteria to
doxycycline, bacteriological sampling and susceptibility testing of micro-organisms
originating from diseased animals are strongly recommended.
Use of the product deviating from the instructions given in the SPC/product literature
may increase the prevalence of bacteria resistant to doxycycline due to the potential
for cross resistance with other tetracyclines and may decrease the effectiveness of
the treatment.
Use of the product should take into account official and local antimicrobial policies.
Avoid administration in oxidized drinking equipment.
See section 4.10 for additional warnings.
Toxic concentrations might also be reached in birds housed in hot, outdoor climates
where water consumption is increased. Birds undergoing treatment should be
monitored for signs of doxycycline toxicosis, including lethargy, inappetance,
inactivity, and passing yellow or green urine. Doxycycline toxicosis caused hepatic
damage and dysfunction that may result in high plasma AST, lactate dehydrogenase,
and bile acids. Doxycycline treatment should be discontinued and general supportive
care started if doxycycline toxicosis is suspected.
The quality of the drinking water may influence the bioavailability of the product. See
Section 4.9.
Revised: August 2021
AN: 01342/2020
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
This product may cause contact dermatitis and/or hypersensitivity reactions if contact
is made with the skin or eyes (powder and solution), or if the powder is inhaled.
People with a possible hypersensitivity to tetracyclines should avoid contact with this
veterinary medicinal product.
Take measures to avoid producing dust or inhalation of dust particles when
incorporating the product into water. Avoid direct contact with skin and eyes when
handling and administering the product.
Wear impermeable gloves (e.g. rubber or latex) and an appropriate dust mask
(disposable half-mask respirator conforming to European Standard EN 149 (FFP2) or
a non-disposable respirator to European Standard EN 140 with a filter to EN 143)
during the preparation and the administration of the solution.
In the event of eye or skin contact, rinse the affected area with large amounts of
clean water and if irritation occurs, seek medical attention.
Wash hands and contaminated skin immediately after handling the product.
If you develop symptoms following exposure such as skin rash, you should seek
medical advice and show this warning to the physician. Swelling of the face, lips or
eyes, or difficulty with breathing are more serious symptoms and require urgent
medical attention.
Do not smoke, eat or drink while handling the product.
In case of accidental ingestion, seek medical attention.
Concurrent administration of doxycycline with any divalent cations (e.g. Ca, FE, Mg,
Al, divalent ions of antacids) should be avoided as this may lead to decreased
bioavailability.
Doxycycline may enhance the effect of anticoagulants.
Do not administer together with kaolin, iron preparations and antacids.
Do not use in conjunction with bactericidal antibiotics, such as penicillins,
cephalosporins and beta-lactam antibiotics due to antagonism of the mode of action.
Al, divalent ions of antacids) should be avoided as this may lead to decreased
bioavailability.
Doxycycline may enhance the effect of anticoagulants.
Do not administer together with kaolin, iron preparations and antacids.
Do not use in conjunction with bactericidal antibiotics, such as penicillins,
cephalosporins and beta-lactam antibiotics due to antagonism of the mode of action.
This veterinary medicinal product does not require any special temperature storage
conditions.
Tightly reclose the 200 g bag after opening in order to protect from light.
Following reconstitution, the medicated solutions should be protected from direct
sunlight.
conditions.
Tightly reclose the 200 g bag after opening in order to protect from light.
Following reconstitution, the medicated solutions should be protected from direct
sunlight.
Not authorised for use in birds intended for human consumption. Not for use in birds
producing or intended to produce eggs for human consumption.
5.
producing or intended to produce eggs for human consumption.
5.
This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.
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