POM-V Prescription Required

DFV Doxivet 200 mg/ml, Solution for Use in Drinking Water for Pigs and Chickens

Active ingredient: Doxycycline Hyclate

Form

Solution

Species

Chickens Pigs

Manufacturer

Divasa - Farmavic S.A

VMD MA No.

33229/4001

What it's used for

Chickens: Where clinical disease is present in the flock, to reduce mortality, morbidity, and clinical signs and to reduce lesions due to Pasteurellosis ca...

Full indications, dosage and side effects ↓

View official SPC (PDF)

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Paying less for Doxycycline Hyclate

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

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Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

DFV Doxivet 200 mg/ml, Solution for Use in Drinking Water for Pigs and Chickens — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

Chickens: Where clinical disease is present in the flock, to reduce mortality, morbidity,
and clinical signs and to reduce lesions due to Pasteurellosis caused by Pasteurella
multocida or to reduce morbidity and lesions in respiratory infections caused by
Ornithobacterium rhinotracheale (ORT).

The recommended dose in pigs is:
12.5 mg doxycycline hyclate (0.054 ml product) per kg body weight per day for 4
consecutive days. If no improvement in clinical signs is seen within this time, the
diagnosis should be reviewed and treatment changed. In case of severe infections the
medication period may be prolonged for a maximum of 8 consecutive days as
determined by the attending veterinary surgeon.
The recommended dose in chickens is: 10 mg doxycycline hyclate (0.043 ml product) per
kg body weight per day for 3-4 consecutive days in case of infections caused by P.
multocida and 20 mg doxycycline hyclate (0.087 ml product) per kg body weight per day
for 3-4 consecutive days in case of infections caused by O. rhinotracheale.
Based on the recommended dose and the number and weight of animals to be treated,
the exact daily concentration of the veterinary medicinal product should be calculated
according to the following formula:
To ensure a correct dosage body weight should be determined as accurately as possible.
The intake of medicated water depends on the clinical condition of the animals. In order
ml veterinary medicinal
product/kg body weight
perday
x
average body weight (kg) of
animals to be treated
average daily water intake (l/animal)
= ml veterinary medicinal
product per litre of drinking
water
AN: 00784/2025 & 00787/2025
to obtain the correct dosage the concentration of doxycycline may need to be adjusted
accordingly.
The use of suitably calibrated measuring equipment is recommended. The daily amount
is to be added to the drinking water such that all medication will be consumed in 24
hours. Medicated drinking water should be refreshed or replaced every 24 hours.
Solubility of the product is pH dependent and it may precipitate if it is mixed in hard
alkaline drinking water. During the treatment period animals should not have access to
other water sources than the medicated water.
Weight can also be used to measure the product quantity to be added in drinking water.
In this case the density correction should be used, according to the following formula:
Amount to be added in drinking water
(g/L)
=
amount to be added in drinking water
(ml/L) x 1.075 (g/ml)

Do not use in case of hypersensitivity to the active substance or to any of the excipients.
Do not use in animals with an impaired liver function.

Pigs and chickens (broiler, pullet, chicken for reproduction).
Very rare
(<1 animal / 10,000 animals treated,
including isolated reports):
Photosensitivity
Allergic reaction
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or its local representative or the national
competent authority via the national reporting system. See the immediate packaging for
respective contact details.
AN: 00784/2025 & 00787/2025

None.
AN: 00784/2025 & 00787/2025

Special precautions for safe use in the target species
Due to likely variability (time, geographical) in susceptibility of bacteria for doxycycline,
especially susceptibility of A. pleuropneumoniae and O. rhinotracheale may differ from
country to country and even farm to farm, bacteriological sampling and susceptibility
testing are recommended.
Use of the veterinary medicinal product should be based on culture and sensitivity of
micro-organisms from diseased cases on farm. If this is not possible, therapy should be
based on local (regional, farm level) epidemiological information about susceptibility of the
target bacteria.
As eradication of the target pathogens may not be achieved, medication should
therefore be combined with good management practices, e.g. good hygiene, proper
ventilation, no overstocking.
Special precautions to be taken by the person administering the veterinary
medicinal product to animals
If you know you are allergic to the tetracycline class of antibiotics, special care should be
taken when handling this veterinary medicinal product or the medicated solution.
During preparation and administration of the medicated drinking water, skin contact with
the veterinary medicinal product should be avoided. Personal protective equipment
consisting of impermeable gloves (e.g. rubber or latex) should be worn when handling
the veterinary medicinal product.
In the event of eye or skin contact, rinse the affected area with large amounts of clean
water and if irritation occurs, seek medical attention. Wash hands and contaminated skin
immediately after handling the veterinary medicinal product.
If you develop symptoms following exposure such as skin rash, you should seek medical
advice and show this warning to the physician. Swelling of the face, lips or eyes, or
difficulty with breathing are more serious symptoms and require urgent medical attention.
Do not smoke, eat or drink while handling the veterinary medicinal product.
Avoid direct contact with skin and eyes when handling the veterinary medicinal product to
prevent sensitisation and contact dermatitis.
Special precautions for the protection of the environment
Not applicable

Do not combine with antibiotics that are bacteriocidal e.g. penicillins or cephalosporins.
Absorption of doxycycline can be decreased in the presence of high quantities of
calcium, iron, magnesium or aluminium in the diet. Do not administer together with
antacids, kaolin and iron preparations.
It is advised that the interval between the administration of other products containing
polyvalent cations should be 1-2 hours because they limit the absorption of tetracyclines.
Doxycycline increases the action of anticoagulants.
The solubility of the product is pH dependent and will precipitate if mixed in alkaline
solution.
Do not store the drinking water in metallic containers.

This veterinary medicinal product does not require any special storage conditions.

Pigs:
- Meat and offal: 4 days
Chickens:
- Meat and offal: 3 days, following a dose rate of 10 mg/kg body weight for 4 days.
- Meat and offal: 12 days, following a dose rate of 20 mg/kg body weight for 4 days.
- Eggs: Not authorised for use in laying birds producing eggs for human
consumption. Do not use within 4 weeks before the start of the laying period

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.