POM-V Prescription Required

Nuflor Minidose 450 mg/ml Solution for Injection for Cattle

Active ingredient: Florfenicol

Form

Injection

Species

Cattle

Manufacturer

Intervet International B.V.

VMD MA No.

06376/3048

What it's used for

metaphylactic treatment.

Full indications, dosage and side effects ↓

View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Florfenicol

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Your prescription rights → VMD register of retailers →

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Nuflor Minidose 450 mg/ml Solution for Injection for Cattle — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

metaphylactic treatment.

Intramuscular use: 20 mg/kg body weight (2 ml/45 kg) to be administered twice 48
hours apart.
The injection should only be given in the neck. The dose volume given at any one
injection site should not exceed 10 ml.
To ensure a correct dosage body weight should be determined as accurately as
possible to avoid underdosing.
Swab septum before removing each dose. Use a dry, sterile needle and syringe.
For 250 ml vials, do not broach the vial more than 25 times.

Do not use in adult bulls intended for breeding purposes.
Do not use in case of hypersensitivity to the active substance or to any of the
excipients.

Cattle:
Very common
(>1 animal / 10 animals
treated):
Injection site pain
1,2,3
,
Injection site swelling
1,4
,
Injection site inflammation
1,5
,
Injection site lesion
1,5
Very rare
(<1 animal / 10,000 animals
treated, including isolated
reports):
Reduced food intake
;
Soft stool
2,6
After injection of the product at the maximum recommended volume of 10 mL per
injection site
Transient
Lasting for some days
Lasting up to 61 days after subcutaneous and up to 24 days after intramuscular
injection
Seen at necropsy and lasting for 37 days after intramuscular injection
Quick and complete recovery upon termination of treatment
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or its local representative or the national
competent authority via the national reporting system. See also section “Contact
details” of the package leaflet.

None.

Special precautions for safe use in the target species:
The product should be used in conjunction with susceptibility testing and take into
account official and local antimicrobial policies.
Do not use where resistance to florfenicol or other amphenicols is known to occur.
Inappropriate use of the veterinary medicinal product may increase the prevalence of
bacteria resistant to florfenicol and other amphenicols.
The prolonged or repeated use of the veterinary medicinal product should be avoided
by improving farming management practices, cleaning and disinfection measures and
eliminating any stress condition.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
Care should be taken to avoid accidental self-injection. In case of self-injection, seek
medical advice immediately and show the package leaflet or the label to the
physician. Avoid direct contact with skin, mouth and eyes. Wash hands after
treatment.
Laboratory studies in rabbits and rats with the excipient N-methylpyrrolidone have
shown evidence of foetotoxic effects. Women of childbearing age, pregnant women
or women suspected of being pregnant should use the veterinary medicinal product
with serious caution to avoid accidental self-injection.
The veterinary medicinal product may cause hypersensitivity (allergy) in some
people. People with known hypersensitivity to florfenicol should avoid contact with the
veterinary medicinal product.
Special precautions for the protection of the environment:
Not applicable.

None known.

This veterinary medicinal product does not require any special temperature storage
conditions.
Keep the vial in the outer carton in order to protect from light.

Meat and offal: Subcutaneous use (at 40 mg/kg body weight, once): 64 days.
Intramuscular use (at 20 mg/kg bodyweight, twice): 37 days.
Not authorised for use in animals producing milk for human consumption.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.