Cadorex 300 mg/ml Solution for Injection for Cattle, Sheep and Pigs
Active ingredient: Florfenicol
Form
Injection
Species
Manufacturer
Industrial Veterinaria SA
VMD MA No.
36547/3011
What it's used for
established before the veterinary medicinal product is used. Sheep: Treatment of ovine respiratory tract infections due to Pasteurella multocida Pigs: Trea...
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Cadorex 300 mg/ml Solution for Injection for Cattle, Sheep and Pigs — SPC Details
Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.
Sheep:
Treatment of ovine respiratory tract infections due to
Pasteurella multocida
Pigs:
Treatment of acute outbreaks of swine respiratory disease caused by strains of
Actinobacillus pleuropneumoniae and .
For treatment
Cattle:
Intramuscular route: 20 mg of florfenicol/kg bodyweight (equivalent to 1 ml of the veterinary
medicinal product/15 kg bodyweight) to be administered twice 48 hours apart using a 16
gauge needle.
Subcutaneous route: 40 mg of florfenicol/kg bodyweight (equivalent to 2 ml of the veterinary
medicinal product/15 kg bodyweight) to be administered once using a 16 gauge needle. The
dose volume given at any one injection site should not exceed 10 ml.
The injection should only be given in the neck.
Sheep:
20 mg of florfenicol/kg bodyweight (equivalent to 1 ml of the veterinary medicinal product/15
kg bodyweight) by intramuscular injection daily for three consecutive days. The volume
administered per injection site should not exceed 4 ml.
Pigs:
15 mg of florfenicol/kg bodyweight (equivalent to 1 ml of the veterinary medicinal product/20
kg bodyweight) by intramuscular injection into the neck muscle twice at 48 hours intervals
using a 16-gauge needle.
The volume administered per injection site should not exceed 3 ml.
For intramuscular, it is recommended to treat animals in the early stages of disease and to
evaluate the response to treatment within 48 hours after the second injection. If clinical signs
of respiratory disease persist 48 hours after the last injection, treatment should be changed
using another formulation or another antibiotic and continued until clinical signs have
resolved.
For metaphylaxis
Cattle:
Subcutaneous use: 40 mg florfenicol/kg bodyweight (equivalent to 2 ml of the veterinary
medicinal product/15 kg bodyweight) to be administered once only using a 16-gauge needle.
The dose volume given at any one injection site should not exceed 10 ml.
The injection should only be given in the neck.
Wipe the stopper before removing each dose. Use a dry sterile needle and syringe.
To ensure a correct dosage, body weight should be determined as accurately as possible.
As the vial should not be broached more than 25 times, the user should select the most
appropriate vial size according to the target species to be treated. When treating groups of
animals in one run, use a draw-off needle that has been placed in the vial stopper to avoid
excess broaching of the stopper. The draw-off needle should be removed after treatment.
Do not use in boars intended for breeding.
Do not use in cases of hypersensitivity to the active substance or to any of the excipients.
Very rare
(<1 animal / 10,000 animals
treated, including isolated
reports):
Reduced food intake
Loose stool
Injection site inflammation
Anaphylactic shock
The treated animals recover quickly and completely upon termination of treatment.
It may persist for 14 days.
Sheep:
Very rare
(<1 animal / 10,000 animals
treated, including isolated
reports):
Reduced food intake
Injection site inflammation
3
The treated animals recover quickly and completely upon termination of the treatment.
It may persist up to 28 days. Typically, these are mild and transient.
Pigs:
Very common
(>1 animal / 10 animals treated):
Pyrexia
5,6
Respiratory depression
, dyspnoea
Diarrhoea
, anal and rectal disorder
(erythema/oedema)
Very rare
(<1 animal / 10,000 animals
treated, including isolated
reports):
Injection site swelling
, injection site inflammation
5
40ºC
These effects were observed in approximately 30% of treated pigs associated with either
moderate depression or moderate dyspnoea a week or more after administration of the
second dose.
Moderate
These effects, may affect 50% of the animals. These effects can be observed for one week
(transient).
It may be observed up to 5 days.
It may be seen up to 28 days.
Reporting adverse events is important. It allows continuous safety monitoring of a veterinary
medicinal product. Reports should be sent, preferably via a veterinarian, to either the
marketing authorisation holder <or its local representative> or the national competent
authority via the national reporting system. See the package leaflet for respective contact
details.
Special precautions for safe use in the target species:
This veterinary medicinal product does not contain any antimicrobial preservative.
The safety of the veterinary medicinal product has not been established in sheep under 7
weeks of age.
Do not use in piglets of less than 2 kg.
Use of the veterinary medicinal product should be based on identification and susceptibility
testing of the target pathogens. Use of the veterinary medicinal product should be in
accordance with official, national and regional antimicrobial policies.
Use of the veterinary medicinal product deviating from the instructions given in the SPC may
increase the prevalence of bacteria resistant to the florfenicol and may decrease the
effectiveness of treatment with amphenicols due to the potential for cross-resistance.
Special precautions to be taken by the person administering the veterinary medicinal product
to animals
This veterinary medicinal product may cause hypersensitivity (allergy).
People with known hypersensitivity to florfenicol, propylene glycol or polyethylene glycols
should avoid contact with the veterinary medicinal product.
Laboratory studies in rabbits and rats with the excipient N-methyl pyrrolidone have shown
evidence of foetotoxic effects. Women of childbearing age, pregnant women or women
suspected of being pregnant should use the veterinary medicinal product with serious
caution to avoid accidental self-injection.
Take care to avoid accidental self-injection. In case of accidental self-injection, seek medical
advice immediately and show the package leaflet or the label to the physician.
Avoid skin or eye contact with the veterinary medicinal product. In case of contact with the
skin or eyes, rinse the affected area immediately with plenty of clean water.
If you develop symptoms following exposure such as skin rash, you should seek medical
advice and show the physician the package leaflet or the label.
Wash hands after use.
Special precautions for the protection of the environment:
The use of this veterinary medicinal product may pose a risk for terrestrial plants,
cyanobacteria and groundwater organisms.
Do not freeze.
Meat and offal: by IM route: 30 days
by SC route: 44 days
Milk: Not authorized for use in animals producing milk for human consumption. Do not use
in pregnant animals which are intended to produce milk for human consumption.
Sheep:
Meat and offal: by IM route: 39 days
Milk: Not authorized for use in animals producing milk for human consumption. Do not use
in pregnant animals which are intended to produce milk for human consumption.
Pigs:
Meat and offal: by IM route: 18 days
This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.
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Related Conditions
Other Products Containing Florfenicol
These products share the same active ingredient and may be suitable alternatives. Always consult your vet.
Amphen 200 mg/g Granules for Use in Drinking Water for Pigs
POM-VHuvepharma NV
Amphen 200 mg/ml Suspension for Use in Drinking Water for Pigs
POM-VHuvepharma NV
Amphen 200 mg/ml Suspension for Use in Drinking Water for Pigs
POM-VHuvepharma NV
Cadorex 300 mg/ml Solution for Injection for Cattle, Sheep and Pigs
POM-VIndustrial Veterinaria SA
Fenflor 300 mg/ml Solution for Injection for Cattle
POM-VKRKA, d.d., Novo mesto
Fenflor 300 mg/ml Solution for Injection for Cattle
POM-VKRKA, d.d., Novo mesto
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