Cadorex 300 mg/ml Solution for Injection for Cattle, Sheep and Pigs
Active ingredient: Florfenicol
Form
Injection
Species
Manufacturer
Industrial Veterinaria SA
VMD MA No.
36547/5011
What it's used for
Pigs: Treatment of acute outbreaks of swine respiratory disease caused by strains of Actinobacillus pleuropneumoniae and .
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Cadorex 300 mg/ml Solution for Injection for Cattle, Sheep and Pigs — SPC Details
Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.
Treatment of acute outbreaks of swine respiratory disease caused by strains of
Actinobacillus pleuropneumoniae and .
Cattle:
Intramuscular route: 20 mg of florfenicol/kg bodyweight (equivalent to 1 ml of
the veterinary medicinal product/15 kg bodyweight) to be administered twice 48
hours apart using a 16 gauge needle.
Subcutaneous route: 40 mg of florfenicol/kg bodyweight (equivalent to 2 ml of
the veterinary medicinal product/15 kg bodyweight) to be administered once
using a 16 gauge needle. The dose volume given at any one injection site
should not exceed 10 ml.
The injection should only be given in the neck.
Sheep:
20 mg of florfenicol/kg bodyweight (equivalent to 1 ml of the veterinary
medicinal product/15 kg bodyweight) by intramuscular injection daily for three
consecutive days. The volume administered per injection site should not exceed
4 ml.
Pigs:
15 mg of florfenicol/kg bodyweight (equivalent to 1 ml of the veterinary
medicinal product/20 kg bodyweight) by intramuscular injection into the neck
muscle twice at 48 hours intervals using a 16-gauge needle.
The volume administered per injection site should not exceed 3 ml.
For intramuscular, it is recommended to treat animals in the early stages of
disease and to evaluate the response to treatment within 48 hours after the
second injection. If clinical signs of respiratory disease persist 48 hours after the
last injection, treatment should be changed using another formulation or another
antibiotic and continued until clinical signs have resolved.
Wipe the stopper before removing each dose. Use a dry sterile needle and
syringe.
To ensure a correct dosage, bodyweight should be determined as accurately as
possible.
As the vial should not be broached more than 25 times, the user should select
the most appropriate vial size according to the target species to be treated.
When treating groups of animals in one run, use a draw-off needle that has
been placed in the vial stopper to avoid excess broaching of the stopper. The
draw-off needle should be removed after treatment.
Do not use in boars intended for breeding.
Do not use in cases of hypersensitivity to the active substance or to any of the
excipients.
Very rare
(<1 animal / 10,000 animals
treated, including isolated
reports):
Reduced food intake
Loose stool
Injection site inflammation
Anaphylactic shock
The treated animals recover quickly and completely upon termination of
treatment.
It may persist for 14 days.
Sheep:
Very rare
(<1 animal / 10,000 animals
treated, including isolated
reports):
Reduced food intake
Injection site inflammation
3
The treated animals recover quickly and completely upon termination of the
treatment.
It may persist up to 28 days. Typically, these are mild and transient.
Pigs:
Very common
(>1 animal / 10 animals
treated):
Pyrexia
5,6
Respiratory depression
, dyspnoea
Diarrhoea
, anal and rectal disorder
(erythema/oedema)
Very rare
(<1 animal / 10,000 animals
treated, including isolated
reports):
Injection site swelling
, injection site
inflammation
5
40ºC
These effects were observed in approximately 30% of treated pigs associated
with either moderate depression or moderate dyspnoea a week or more after
administration of the second dose.
Moderate
These effects, may affect 50% of the animals. These effects can be observed
for one week (transient).
It may be observed up to 5 days.
It may be seen up to 28 days.
Reporting adverse events is important. It allows continuous safety monitoring of
a veterinary medicinal product. Reports should be sent, preferably via a
veterinarian, to either the marketing authorisation holder or its local
representative or the national competent authority via the national reporting
system. See the package leaflet for respective contact details.
Special precautions for safe use in the target species:
This veterinary medicinal product does not contain any antimicrobial
preservative.
The safety of the veterinary medicinal product has not been established in
sheep under 7 weeks of age.
Do not use in piglets of less than 2 kg.
Use of the veterinary medicinal product should be based on identification and
susceptibility testing of the target pathogens. Use of the veterinary medicinal
product should be in accordance with official, national and regional antimicrobial
policies.
Use of the veterinary medicinal product deviating from the instructions given in
the SPC may increase the prevalence of bacteria resistant to the florfenicol and
may decrease the effectiveness of treatment with amphenicols due to the
potential for cross-resistance.
Special precautions to be taken by the person administering the veterinary
medicinal product to animals
This veterinary medicinal product may cause hypersensitivity (allergy).
People with known hypersensitivity to florfenicol, propylene glycol or
polyethylene glycols should avoid contact with the veterinary medicinal product.
Laboratory studies in rabbits and rats with the excipient N-methyl pyrrolidone
have shown evidence of foetotoxic effects. Women of childbearing age,
pregnant women or women suspected of being pregnant should use the
veterinary medicinal product with serious caution to avoid accidental self-
injection.
Take care to avoid accidental self-injection. In case of accidental self-injection,
seek medical advice immediately and show the package leaflet or the label to
the physician.
Avoid skin or eye contact with the veterinary medicinal product. In case of
contact with the skin or eyes, rinse the affected area immediately with plenty of
clean water.
If you develop symptoms following exposure such as skin rash, you should seek
medical advice and show the physician the package leaflet or the label.
Wash hands after use.
Special precautions for the protection of the environment:
Not applicable.
None known.
Do not freeze.
Meat and offal: by IM route: 30 days
by SC route: 44 days
Milk: Not authorized for use in animals producing milk for human consumption.
Do not use in pregnant animals which are intended to produce milk for human
consumption.
Sheep:
Meat and offal: by IM route: 39 days
Milk: Not authorized for use in animals producing milk for human consumption.
Do not use in pregnant animals which are intended to produce milk for human
consumption.
Pigs:
Meat and offal: by IM route: 18 days
This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.
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Related Conditions
Other Products Containing Florfenicol
These products share the same active ingredient and may be suitable alternatives. Always consult your vet.
Amphen 200 mg/g Granules for Use in Drinking Water for Pigs
POM-VHuvepharma NV
Amphen 200 mg/ml Suspension for Use in Drinking Water for Pigs
POM-VHuvepharma NV
Amphen 200 mg/ml Suspension for Use in Drinking Water for Pigs
POM-VHuvepharma NV
Cadorex 300 mg/ml Solution for Injection for Cattle, Sheep and Pigs
POM-VIndustrial Veterinaria SA
Fenflor 300 mg/ml Solution for Injection for Cattle
POM-VKRKA, d.d., Novo mesto
Fenflor 300 mg/ml Solution for Injection for Cattle
POM-VKRKA, d.d., Novo mesto
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