Amphen 200 mg/g Granules for Use in Drinking Water for Pigs

10 mg florfenicol/kg bodyweight per day in drinking water for 5 consecutive days.
The daily amount of veterinary medicinal product to be mixed with drinking water can be
calculated based on the Total Body Weight (TBW) of the group to be treated with the
following formula:
Total Body Weight of the group (TBW) in kgAmount of veterinary
medicinal product (in grams)
per day*
=
* to be mixed with the estimated total water consumption of the group in 24 hours.
The examples of medicated drinking water in the table below are calculated by applying
the formula and by assuming that pigs drink 8% or 10% of their bodyweight.
TBW of the
group (kg
Veterinary
medicinal
product (g)
Estimated daily
water
consumption (L)
Veterinary
medicinal
product grams
per 10 litres of
water
Pigs drinking 500 kg25 g40 L

Revised December 2024
AN: 00622/2024 & 00623/2024
1000 kg50 g80 L8% of their
bodyweight
5000 kg250 g400 L6.25 g/10 L500 kg25 g50 L1000 kg50 g100 LPigs drinking
10%
bodyweight
5000 Kg250 g500 L
5 g/10 L

The maximum solubility of the veterinary medicinal product granules is 2.5 g/L at 10 °C
and 20 °C and 2.0 g/L at 5 °C. Dissolution may take up to 30 minutes. During
dissolution the solution should be stirred for at least 5 minutes at 50 RPM. Solutions
should be checked visually for complete dissolution.
FOR BULK TANK:
Any solution for use in a header tank must be limited to not more than the maximum
solubility.
FOR PROPORTIONER:
For stock solutions and when using a proportioner, take care not to exceed the
maximum solubility which can be achieved under the given conditions. Adjust flow rate
settings of the dosing pump according to concentration of the stock solution and water
intake of the animals to be treated.
To treat 5,000 kg of pigs, drinking 10% of their bodyweight, at the dose rate of
10 mg/kg:
1. Fill the proportioner with 100 L drinking water (temperature not below 10
°C).
2. Add 250 g of veterinary medicinal product to the proportioner.
3. Mix thoroughly until visually dissolved.
4. Set the proportioner to 20%.
5. Turn on the proportioner.
In order to ensure correct dosing and to prevent underdosing, the body weight of the
group should be calculated as precisely as possible and water consumption should be
monitored. The required quantity of granules should be measured by suitably calibrated
weighing equipment.
The uptake of water depends on several factors including the age, the clinical state of
the animals and the local conditions such as ambient temperature and humidity. The
daily water consumption can be underestimated (e.g. reduced to 6% of bodyweight) in
order to ensure total consumption of medicated water during the day (fresh drinking
water can be made available following the consumption of the medicated water). If it is
not possible to obtain sufficient uptake of medicated water animals should be treated
parenterally.
Medicated drinking water should be replaced every 24 hours.