POM-V Prescription Required

Nuflor 300 mg/ml Solution for Injection for Cattle and Sheep

Active ingredient: Florfenicol

Form

Injection

Species

Cattle Sheep

Manufacturer

Intervet International B.V.

VMD MA No.

06376/5053

What it's used for

Metaphylactic and therapeutic treatment of respiratory tract infections in cattle due to Mannheimia haemolytica, Pasteurella multocida and Histophilus somn...

Full indications, dosage and side effects ↓

View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Florfenicol

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

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Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Nuflor 300 mg/ml Solution for Injection for Cattle and Sheep — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

Metaphylactic and therapeutic treatment of respiratory tract infections in cattle due to
Mannheimia haemolytica, Pasteurella multocida and Histophilus somni
presence of the disease in the herd should be established before metaphylactic
treatment.
Sheep:
Treatment of ovine respiratory tract infections due to Mannheimia haemolytica and
Pasteurella multocida

To ensure a correct dosage body weight should be determined as accurately as
possible to avoid underdosing.
The vials should not be broached more than 20 times. User should therefore select
the most appropriate vial size according to the target species to be treated.
When treating groups of animals at the same time, use of a draw-off needle in the
vial stopper is recommended to avoid excess stopper broaching. The draw-off needle
should be removed after treatment.
For treatment
Cattle:
Intramuscular use: 20 mg/kg bodyweight (1 ml/15 kg) to be administered twice
48 hours apart using a 16 gauge needle.
Subcutaneous use: 40 mg/kg bodyweight (2 ml/15 kg) to be administered once only
using a 16 gauge needle. The dose volume given at any one injection site should not
exceed 10 ml.
The injection should only be given in the neck.
Sheep:
Intramuscular use: 20 mg florfenicol/kg bodyweight (1 ml/15 kg) to be administered
daily for three consecutive days. The volume administered per injection site should
not exceed 4 ml.
Pharmacokinetic studies showed that mean plasma concentrations remain above
MIC90 (1 μg/ml) for up to 18 hours after administration of the veterinary medicinal
product at the recommended treatment dose. The pre-clinical data supported the
recommended treatment interval (24 hours) for target pathogens with MIC up to
1 μg/ml.
For metaphylaxis
Cattle:
Subcutaneous use: 40 mg/kg bodyweight (2 ml/15 kg) to be administered once only
using a 16 gauge needle. The dose volume given at any one injection site should not
exceed 10 ml.
The injection should only be given in the neck.

Do not use in adult bulls and rams intended for breeding purposes.
Do not use in cases of hypersensitivity to the active substance or to any of the
excipients.

Cattle:
Very rare
(<1 animal / 10,000 animals
treated, including isolated
reports):
Reduced food intake
;
Loose stool
;
Injection site inflammation
, Injection site lesion
;
Anaphylaxis.
Quick and complete recovery upon termination of treatment.
May persist for 14 days after intramuscular and subcutaneous administration.
Sheep:
Very rare
(<1 animal / 10,000 animals
treated, including isolated
reports):
Reduced food intake
;
Injection site inflammation
, Injection site lesion
.
Quick and complete recovery upon termination of treatment.
Mild and may persist up to 28 days after intramuscular administration.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or its local representative or the national
competent authority via the national reporting system. See the package leaflet for
respective contact details.

None.

Special precautions for safe use in the target species:
The veterinary medicinal product should be used in conjunction with susceptibility
testing and take into account official and local antimicrobial policies.
The safety of the product has not been established in sheep younger than 7 weeks of
age.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
People with known hypersensitivity to propylene glycol and polyethylene glycols
should avoid contact with the veterinary medicinal product. In case of accidental
contact with skin or eyes, rinse immediately with plenty of water.
In case of accidental self-injection, seek medical advice immediately and show the
package leaflet or the label to the physician.
Laboratory studies in rabbits and rats with the excipient N-methyl pyrrolidone have
shown evidence of fetotoxic effects. Women of childbearing age, pregnant women or
women suspected of being pregnant should use the veterinary medicinal product with
serious caution to avoid accidental self-injection.
Special precautions for the protection of the environment:
Not applicable.

No data available.

Do not store above 25 °C.
Do not refrigerate.
Protect from frost.

Meat and offal
Cattle: IM use (20 mg/kg bodyweight, twice): 30 days.
SC use (40 mg/kg bodyweight, once): 44 days.
Sheep: 39 days.
Milk
Not authorised for use in animals producing milk for human consumption including
pregnant animals intended to produce milk for human consumption.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.