POM-V Prescription Required

Norfenicol 300 mg/ml Solution for Injection for Cattle and Pigs

Active ingredient: Florfenicol

Form

Injection

Species

Cattle Pigs

Manufacturer

Norbrook Laboratories Limited

VMD MA No.

02000/4316

What it's used for

Cattle: Treatment of respiratory tract infections in clinically diseased cattle due to Mannheimia haemolytica, Pasteurella multocida and Histophilus somni...

Full indications, dosage and side effects ↓

View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Florfenicol

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Your prescription rights → VMD register of retailers →

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Norfenicol 300 mg/ml Solution for Injection for Cattle and Pigs — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 26 Mar 2026.

Cattle:
Treatment of respiratory tract infections in clinically diseased cattle due to
Mannheimia haemolytica, Pasteurella multocida and Histophilus somni
to florfenicol.
Pigs:
Treatment of acute outbreaks of respiratory disease caused by strains of
Actinobacillus pleuropneumoniae and susceptible to florfenicol.

To ensure correct dosage body weight should be determined as accurately as
possible.
Swab septum before removing each dose.
Use a dry sterile needle and syringe.
Do not broach the vial more than 25 times.
Cattle:
Intramuscular Injection: 20 mg/kg bodyweight (1 ml/15 kg) to be administered twice
48 hours apart using a 16-gauge needle.
Subcutaneous Injection: 40 mg/kg bodyweight (2 ml/15 kg) to be administered once
only using a 16-gauge needle.
The dose volume given at any one injection site should not exceed 10 ml.
The injection should only be given in the neck.
Pigs:
Intramuscular Injection: 15 mg/kg bodyweight (1 ml per 20 kg) into the neck muscle
twice at 48 hour intervals using a 16-gauge needle.
The volume administered per injection site should not exceed 3 ml.
It is recommended to treat cattle and Pigs in the early stages of disease and to
evaluate the response to treatment within 48 hours after the second injection.

Revised: February 2026
AN: 03569/2025
If clinical signs of respiratory disease persist 48 hours after the last injection,
treatment should be changed using another formulation or another antibiotic and
continued until clinical signs have resolved.

Do not use in adult bulls or boars intended for breeding purposes.
Do not use in cases of hypersensitivity to the active substance or to any of the
excipients.
Do not use in cases of known resistance to florfenicol.

Cattle:
Administration of the product by the intramuscular or subcutaneous route may cause
inflammatory lesions (swelling and hardness) at the injection site which may persist
for 31 days. A decrease in food consumption and transient softening of the faeces
may occur during the treatment period. The treated animals recover quickly and
completely upon termination of treatment.
In very rare cases, anaphylactic shock has been reported in cattle.

Revised: February 2026
AN: 03569/2025
Pigs:
Commonly observed adverse effects are transient diarrhoea and/or peri-anal and
rectal erythema/oedema which may affect 50 % of the animals. These effects can be
observed for one week.
Under field conditions approximately 30 % of treated pigs presented with pyrexia
(40˚C)
more after administration of the second dose.
The frequency of adverse reactions is defined using the following convention:
- very common (more than 1 in 10 animals displaying adverse reaction(s) during the
course of one treatment)
- common (more than 1 but less than 10 animals in 100 animals)
- uncommon (more than 1 but less than 10 animals in 1,000 animals)
- rare (more than 1 but less than 10 animals in 10,000 animals)
- very rare (less than 1 animal in 10,000 animals, including isolated reports)

None.

Revised: February 2026
AN: 03569/2025

Special precautions for use in animals
Do not use in piglets of less than 2 kg.
Use a suitable draw-off needle or automatic dosing syringe to avoid excessive
puncturing of the closure. Florfenicol should be used for treatment of severe
infections only.
Use of the product should be based on susceptibility testing of the bacteria isolated
from the animal. If this is not possible, therapy should be based on local (regional,
farm level) epidemiological information about susceptibility of the target bacteria.
Official national and regional antimicrobial policies should be taken into account
when the product is used.
Use of the product deviating from the instructions given in the SPC may increase the
prevalence of bacteria resistant to the florfenicol and may decrease the effectiveness
of treatment with other antimicrobials (e.g. ceftiofur) due to the potential for cross
resistance.
Special precautions to be taken by the person administering the veterinary
medicinal product to animals
This product may cause allergic reactions in those that are sensitive.
People with known hypersensitivity to florfenicol or any of the excipients should avoid
contact with the veterinary medicinal product.
Take care to avoid accidental self-injection. In case of accidental self-injection, seek
medical advice immediately and show the package leaflet or the label to the
physician.
The product may cause irritation if it comes into contact with the skin, mucous
membranes or eyes. Avoid direct contact with skin, mouth and eyes. In case of
contact with the skin or eyes, rinse the affected area immediately with plenty of clean
water. If accidental ingestion occurs, rinse the mouth with plenty of water and seek
medical advice immediately.
Wash hands after use.
Special precautions for use – Other precautions:
The use of this veterinary medicinal product may pose a risk for terrestrial plants,
cyanobacteria and groundwater organisms.

None known.

Protect from light. Keep container in the protective sleeve/outer carton.

Cattle
Meat and offal:
By intramuscular injection (at 20 mg/kg, twice): 39 days
By subcutaneous injection (at 40 mg/kg, once): 44 days
Milk: Not permitted for use in lactating animals producing milk for human
consumption.
Pigs
Meat and offal: 22 days
5.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.