POM-V Prescription Required

Nifencol 300 mg/ml Solution for Injection for Cattle and Pigs

Active ingredient: Florfenicol

Form

Injection

Species

Cattle Pigs

Manufacturer

Vetpharma Animal Health, S.L

VMD MA No.

32509/4011

What it's used for

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Full indications, dosage and side effects ↓

View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Florfenicol

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Your prescription rights → VMD register of retailers →

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Nifencol 300 mg/ml Solution for Injection for Cattle and Pigs — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

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Cattle: Intramuscular or subcutaneous injection
Pig: intramuscular injection
Cattle:
Treatment
IM route: 20 mg florfenicol /kg bodyweight (1ml of the product/15kg) to be
administered twice 48 hours apart using a 16 gauge needle.
SC route: 40 mg florfenicol /kg bodyweight (2ml of the product/15kg) to be
administered once only using a 16 gauge needle.
Metaphylaxis
SC route: 40 mg florfenicol/kg bodyweight (2ml of the product/15kg) to be
administered once only using a 16 gauge needle.
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Pigs:
15 mg florfenicol/kg bodyweight (1 ml of the product / 20 kg) by intramuscular
injection twice at 48 hour intervals using a 16-gauge needle.
The dose volume given at any one injection site should not exceed 10ml for
both routes of administration (intramuscular and subcutaneous) in cattle and 3
ml in pigs. The injection should only be given in the neck in both target species.
To ensure a correct dosage body weight of the animals should be determined
as accurately as possible to avoid underdosing.
It is recommended to treat animals in the early stages of disease and to
evaluate the response to treatment within 48 hours after the second injection.
clinical signs of respiratory disease persist 48 hours after the last injection or if
relapse occurs, treatment should be changed using another formulation or
another antibiotic and continued until clinical signs have resolved.
Swab septum before removing each dose. Use a dry sterile needle and syringe.
Do not broach the stopper of vial more than 25 times.

Do not use in adult bulls intended for breeding purposes.
Do not use in animals suffering from hepatic and renal diseases.
Do not use if there is a risk of gastrointestinal bleeding or in cases where there is
evidence of altered hemostasis.
Do not use in animals suffering from cardiac diseases.
Do not use in cases of hypersensitivity to the active substances or to any of the
excipients.

completely upon termination of treatment.
Administration of the product by the intramuscular and subcutaneous routes
may cause inflammatory lesions at injection site which persist for 14 days.
On very rare occasions, anaphylactic reactions have been reported in cattle.
In pigs, commonly observed adverse effects are transient diarrhoea and/or peri-
anal and rectal erythema/oedema which may affect 50% of the animals. These
effects can be observed for one week. Under field conditions approximately
30% of treated pigs presented with pyrexia (40C) associated with either
moderate depression or moderate dyspnea a week or more after administration
of the second dose.
Transient swelling lasting up to 5 days may be observed at the site of injection.
Inflammatory lesions at the injection site may be seen up to 28 days.
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The frequency of adverse reactions is defined using the following convention:
-
reaction(s))
-
-
treated)
-
-
reports).

None.

Special precautions for safe use in the target species:
Use of the product should be based on susceptibility testing of the bacteria isolated
from the animal. If this is not possible, therapy should be based on local (regional,
farm level) epidemiological information about susceptibility of the target bacteria.
Official and local antimicrobial policies should be taken into account when the
product is used.
Use of the product deviating from the instructions given in the SPC may increase the
prevalence of bacteria resistant to florfenicol.
Avoid use in dehydrated, hypovolaemic or hypotensive animals as there is a potential
risk of increased renal toxicity. Concurrent administration of potentially nephrotoxic
drugs should be avoided.
Repeated daily dosing has been associated with abomasal erosions in the pre-
ruminant calf. The product should be used with caution in this age group.
The safety of the product has not been tested in calves of 3 weeks of age or less.
Flunixin is toxic to avian scavengers. Do not administer to animals susceptible to
enter wild fauna food chain. In case of death or sacrifice of treated animals, ensure
that they are not made available to wild fauna.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
This product may cause adverse effects. Care should be taken to avoid accidental
self-injection.
In case of accidental self-injection, seek medical advice immediately and show the
package leaflet or the label to the physician.
Laboratory studies in rabbits and rats with the excipient N-methyl pyrrolidone have
shown evidence of foetotoxic effects. Women of childbearing age, pregnant women
or women suspected of being pregnant should use the veterinary medicinal product
with serious caution to avoid accidental self-injection.
This veterinary medicinal product may cause hypersensitivity reactions (allergy).
People with known hypersensitivity to propylene glycol and polyethylene glycols
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should avoid contact with the veterinary medicinal product. If you develop symptoms
following exposure, such as skin rash, swelling of the face, lips or eyes or difficulty
with breathing, you should seek medical advice immediately and show the package
leaflet or the label to the physician.
Wash hands after use.

interaction
None known.

Keep the vial in the outer carton in order to protect from light.

Cattle:
Meat and offal: by IM (at 20 mg/kg bodyweight, twice): 30 days
by SC (at 40 mg/kg bodyweight, once): 44 days
Milk: Not authorised for use in cattle producing milk for human consumption,
including during the dry period.
Pigs:
Meat and offal: 18 days
5

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.