POM-V Prescription Required

Hipragumboro G97

Active ingredient: Infectious bursal disease virus

Form

Tablet

Species

Chickens

Manufacturer

Laboratorios Hipra SA

VMD MA No.

17533/5026

What it's used for

For active immunisation of broilers with insignificant levels of maternally derived antibodies (ELISA of 500 or below) to reduce mortality, clinical signs...

Full indications, dosage and side effects ↓

View official SPC (PDF)

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Clinical information

Hipragumboro G97 — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

For active immunisation of broilers with insignificant levels of maternally derived
antibodies (ELISA of 500 or below) to reduce mortality, clinical signs and bursal
lesions of Gumboro disease. Such birds can be vaccinated from one day of age. The
onset of immunity is 14 days post vaccination and the duration 43 days post
vaccination.

Break the vacuum inside the vial by inoculation of 10 ml of drinking water without
chlorine or disinfectants. Shake gently until complete resuspension of the freeze-dried
powder before administration.
Posology:
Serologically negative birds can be vaccinated from one day of age. The optimum age
for vaccination may be calculated using the level of maternal antibody in the chicks at
day old (Kouwenhoven’s formula) by testing at least 18 birds (preferably 24) of the
flock according to the following table. All birds should be given a single vaccination
only.
MEAN ELISA TITRE AT 1 DAY OF
AGE
OPTIMUM AGE FOR VACCINATION
(DAYS)
≤5001≤7502-3≤10004≤12505-6≤15007≤20009≤250011≤300012-13≤350014≤400015-16≤450017≤500018≤550019≤600020
Method of administration:
The volume of water for reconstitution depends on the age of the birds and the
management practice. Generally, 2 litres of water per 1,000 broilers for every day of
age are needed. Hence, 1,000 14 day broilers would need 28 litres of water to
reconstitute the 1,000 doses of vaccine. If the birds have higher or lower water
requirements, adjust the volumes accordingly.
The way in which this vaccine is administered is critical. The following management
considerations have been found to improve the vaccine intake:
Water should be withheld for 1-2 hours before vaccination to ensure that all
reconstituted vaccine is consumed within 1-2 hours.
For bell drinkers: go round the house emptying and cleaning the drinkers during the
water withholding period. Mix up the vaccine according to the recommendations and at
the end of the water withholding period go round all the drinkers and fill them with
water containing vaccine.
For nipple drinkers: a considerable amount of residual water may remain in the lines
after the water withholding period. It is recommended to drain the lines and load them
with water which contains vaccine before allowing the birds to have access to the
nipples. Mix up the vaccine and apply to the tank. Calculate the volume that is left in
the tank below the outlet valve and be sure to take this volume of water into account
when calculating the number of doses to be added.
Always make sure that there is food available when vaccinating (birds will not drink if
they have no food to eat). Turn on mains water when all the water containing vaccine
has been consumed.

Do not vaccinate sick birds.
Do not use in infected flocks showing clinical signs.
Since no studies to demonstrate the safety of this vaccine when it is administered to
layers and breeders have been carried out, its use is not recommended for these
categories of the target species (see section 4.7).

The administration of a single dose causes lymphocyte depletion in the bursa of
Fabricius (in 50-75% of the follicles). Lymphocyte repopulation is observed from 14
days post vaccination onwards, at 28 days post vaccination there is still some
depletion remaining (5-25 % of follicles). This lymphocyte depletion does not result in
an immunosuppressive effect.

Use only in flocks with low levels of maternal antibodies (mean ELISA titres 500).
The optimum day of vaccination of broilers with maternal antibodies is calculated
according to the Kouwenhoven’s formula (see section 4.9. posology).
Due to its residual pathogenicity to the bursa the vaccine should be used only in areas
contaminated with vvIBDV, except for infected flocks showing clinical signs.
See section 4.3.

Special precautions for use in animals
- Do not use water with chlorine or disinfectants to reconstitute the vaccine.
- The vaccine strain spreads to unvaccinated chickens.
- Appropriate veterinary and husbandry measures should be taken to avoid spread to
susceptible species.
Special precautions to be taken by the person administering the veterinary
medicinal product to animals.
- Wash and disinfect hands and equipment after use.
- In the case of accidental ingestion, contact with the eyes, or spillage onto the skin
seek medical advice immediately and show the package leaflet or the label to the
physician.

No information is available on the compatibility of this vaccine with any other.
Therefore the safety and efficacy of this product when used with any other (either
when used on the same day or different times) has not been demonstrated.

Store and transport refrigerated (2ºC -8 ºC).
Protect from light.

Special precautions for use in animals
- Do not use water with chlorine or disinfectants to reconstitute the vaccine.
- The vaccine strain spreads to unvaccinated chickens.
- Appropriate veterinary and husbandry measures should be taken to avoid spread to
susceptible species.
Special precautions to be taken by the person administering the veterinary
medicinal product to animals.
- Wash and disinfect hands and equipment after use.
- In the case of accidental ingestion, contact with the eyes, or spillage onto the skin
seek medical advice immediately and show the package leaflet or the label to the
physician.
4.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.