AviPro Precise Lyophilisate for Use in Drinking Water

from the age of 7 days onwards.
The determination of the vaccination date is depending on a number of factors
including status of maternal antibodies, type of bird, infection pressure, housing and
management conditions.
Maternally derived antibodies (MDA) potentially interfere with the take of live IBD
vaccines. The optimum age for vaccination therefore depends on both, the level of
MDA against IBD in the flock and the capability of the vaccine to take in face of these
MDA (“break-through-titre”). A high homogeneity of the flock MDA levels is important
to define the timing of vaccination and guarantees the better take of the vaccine. To
predict the age, when MDA have sufficiently decreased to allow effective vaccination,
it is advised to test serum samples of at least 24 chicks by serology and apply the
“Deventer Formula” for intermediate vaccines. For chicks from fully vaccinated or
field virus infected breeders this may be at 14 days or more. Serologically negative
birds may be vaccinated from day 7.
A further vaccination 7 days after the first may be necessary particularly in flocks
where antibody levels vary widely between birds (i.e. CV greater than 30 %), or stock
originates from different sources.
Broilers:
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Layers/Breeders:
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Dosage and administration:
Drinking water application:
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required. Do not split large vials to vaccinate more than 1 house or drinking
system, as this may lead to mixing errors.
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clean and free of any trace of disinfectants, detergents etc.
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disinfectants to ensure the viability of the vaccine. Use only fresh water
preferably non-chlorinated and free from metal-ions. Low-fat skimmed milk
powder (i.e. < 1 % fat) may be added to the water (2 – 4 grams per litre) or
skimmed milk (20 – 40 ml per litre of water) to improve the water quality and to
increase the stability of the virus. This, however, has to be done 10 minutes
prior to reconstitution of the vaccine.
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Care should be taken to empty the ampoule and its top completely by rinsing
them in water.
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vaccine is applied. All tubing should be emptied of plain water, so that the
drinkers contain only vaccine water. If water is still present, drain lines before
applying vaccine.
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Birds drinking behaviour varies, it may be necessary to withhold water on some
sites prior to vaccination in order to ensure that all birds drink during the
vaccination period.
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birds in up to 2 hours. As a general rule, apply reconstituted vaccine to cold and
fresh water at the rate of 1 000 doses of vaccine to 1 litre of water per day of
age for 1 000 chickens, e.g. 10 litres would be needed for 1 000, 10 days old
chickens. Under hot climates or with heavy breeds this amount may have to be
increased up to a maximum of 40 litres per 1 000 birds. If in doubt, measure
water intake the day before administering vaccine.
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do not have access to unmedicated water during vaccination.
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hours.