POM-V Prescription Required

Avishield IBD Plus, Lyophilisate for Use in Drinking Water for Chickens

Active ingredient: Infectious bursal disease virus

Form

Lyophilisate

Species

Chickens

Manufacturer

IZO S.r.l a socio unico

VMD MA No.

61812/5002

What it's used for

For active immunisation of chickens (broilers, future layers and breeders) with maternally derived antibodies (break-through titre: IDEXX ELISA units) to r...

Full indications, dosage and side effects ↓

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1

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2

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Prescription required

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Clinical information

Avishield IBD Plus, Lyophilisate for Use in Drinking Water for Chickens — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

For active immunisation of chickens (broilers, future layers and breeders) with
maternally derived antibodies (break-through titre: IDEXX ELISA units) to
reduce clinical disease and bursal lesions due to infection caused by Avian Infectious
Bursal Disease (IBD) viruses.
Chickens can be vaccinated from 10 days of age.
Onset of immunity: 2 weeks after vaccination.
Duration of immunity: 5 weeks after vaccination.

None.

Chickens (broilers, future layers and breeders):
Very common
(>1 animal / 10 animals
treated):
Bursa of Fabricius lymphocyte depletion
a
a
Significant, lymphocyte depletion in the bursa of Fabricius (in 26-50% of the
follicles) was observed 7 days after vaccine take in laboratory studies after
administration of a 10-fold overdose. Lymphocyte repopulation is observed from 21
days post vaccination onwards. At 28 days post vaccination there is still some
depletion remaining (1-25 % of follicles). Complete repopulation of the bursae by
lymphocytes has taken place by 35 days after vaccination.
The vaccine-related lymphocyte depletion was not associated with
immunosuppression.

Revised: March 2026
AN: 04197/2025
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or its local representative or the national
competent authority via the national reporting system. See also section 16 of the
package leaflet for respective contact details.

See section Amount(s) to be administered and administration route
Vaccinate healthy animals only.

Revised: March 2026
AN: 04197/2025

Special precautions for use in animals
The vaccine strain can spread to susceptible, unvaccinated chickens following
vaccination for at least 5 days. The spread does not induce clinical signs.
It is possible that the vaccine virus spreads to non-target susceptible species.
Care should be taken to ensure that the vaccine virus does not spread to
unvaccinated birds. Therefore, all birds in a flock should be vaccinated at the same
time to reduce the risk of bird to bird transmission. Vaccinated birds should not be
mixed with unvaccinated birds. Hygiene measures should be taken to prevent spread
to other flocks. Vaccination of all chickens on the premises is recommended.
Housing needs to be disinfected prior to restocking.
Given that this vaccine is an intermediate plus strain of IBDV, this vaccine should
only be used after it has been determined that there is an epidemiological need.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
Wash and disinfect hands and equipment after vaccination.
Special precautions for the protection of the environment
Not applicable.
Other precautions
Not applicable.

No information is available on the safety and efficacy of this vaccine when used with
any other veterinary medicinal product. A decision to use this vaccine before or after
any other veterinary medicinal product therefore needs to be made on a case by
case basis.

Store in a refrigerator (2C–8C).
Protect from light.
Do not freeze.

Revised: March 2026
AN: 04197/2025

Zero days.
5. IMMUNOLOGICAL PROPERTIES
Pharmacotherapeutic group: Immunologicals for Aves, Domestic fowl, live viral
vaccine, avian infectious bursal disease virus (gumboro disease).
ATCvet code: QI01AD09.
To stimulate active immunity against Infectious Bursal Disease virus in chickens.
The vaccine strain is an intermediate plus strain with an average bursal lesion score
of 0.4 at 28 days after administration of 10-times the maximum dose.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.