Florkem 300 mg/ml Solution for Injection for Cattle and Pigs
Active ingredient: Florfenicol
Form
Injection
Species
Manufacturer
Ceva Sante Animale
VMD MA No.
14966/3081
What it's used for
Pigs: Treatment of acute outbreaks of swine respiratory disease caused by strains of Actinobacillus pleuropneumoniae and susceptible to florfenicol
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Florkem 300 mg/ml Solution for Injection for Cattle and Pigs — SPC Details
Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.
Treatment of acute outbreaks of swine respiratory disease caused by strains of
Actinobacillus pleuropneumoniae and susceptible to florfenicol
20 mg florfenicol per kg bodyweight, i.e. 1 ml of solution per 15 kg bodyweight, twice
48 hours apart.
Pigs :
15 mg florfenicol per kg bodyweight, i.e. 1 ml of solution per 20 kg bodyweight, twice
48 hours apart.
The dose volume given at any one injection site should not exceed 10 ml in cattle
and 3 ml in pigs.
To ensure a correct dosage body weight should be determined as accurately as
possible to avoid underdosing.
It is recommended to treat animals in the early stages of disease and to evaluate the
response to treatment within 48 hours after the second injection. If clinical signs of
respiratory disease persist 48 hours after the last injection, treatment should be
changed using another formulation or another antibiotic and continued until clinical
signs have resolved.
Do not administer in cases of hypersensitivity to the active ingredient or any of the
excipients.
Very rare
(< 1 animal / 10,000 animals
treated, including isolated
reports):
Reduced food intake
Soft stool
1,2
Injection site reaction
2,3
(e.g inflammation, lesion)
Treated animals recover quickly and completely upon termination of treatment.
Transient.
May persist for up to 28 days.
Pigs:
Common
(1 to 10 animals / 100 animals
treated):
Anal and rectal disorder (e.g. erythema, oedema)
,
Diarrhoea
1,2
Very Rare
(< 1 animal / 10,000 animals
treated, including isolated
reports):
Injection site reaction
2,3
(e.g inflammation, lesion)
May affect 50% of the animals and be observed for up to one week.
Transient.
Disappear within 28 days.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or the national competent authority via the
national reporting system. See the package leaflet for respective contact details.
Special precautions for safe use in the target species:
Wipe the stopper before removing each dose. Use a dry, sterile needle and
syringe. Do not use in piglets of less than 2 kg.
Under field conditions, approximately 30% of treated pigs presented with pyrexia
(40°C) associated with either moderate depression or moderate dyspnoea a week
or more after administration of the second dose.
Use of product should be based on susceptibility testing of the bacteria isolated from
the animal. If this is not possible, therapy should be based on local (regional, farm
level) epidemiological information about susceptibility of the target bacteria.
Official national and regional antimicrobial policies should be taken into account
when the product is used.
Use of the product deviating from the instructions given in the SPC may increase the
prevalence of bacteria resistant to the florfenicol and may decrease the
effectiveness of treatment with other antimicrobials, due to the potential for cross-
resistance. Particular attention should be paid to improving farming practices to
avoid any stress condition (improving management practices and by cleaning and
disinfection).
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
Care should be taken when handling the product to avoid accidental self-injection. In
case of accidental self-injection, seek medical advice, and show the package leaflet
or the label to the physician.
People with known hypersensitivity to the components of the formulation should
avoid contact with the product.
Wash hands after handling the product.
Special precautions for the protection of the environment:
Not applicable
.
Meat and offal: 37 days
Milk: Not permitted for use in lactating animals producing milk for human
consumption.
Pigs:
Meat and offal: 18 days
This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.
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Related Conditions
Other Products Containing Florfenicol
These products share the same active ingredient and may be suitable alternatives. Always consult your vet.
Amphen 200 mg/g Granules for Use in Drinking Water for Pigs
POM-VHuvepharma NV
Amphen 200 mg/ml Suspension for Use in Drinking Water for Pigs
POM-VHuvepharma NV
Amphen 200 mg/ml Suspension for Use in Drinking Water for Pigs
POM-VHuvepharma NV
Cadorex 300 mg/ml Solution for Injection for Cattle, Sheep and Pigs
POM-VIndustrial Veterinaria SA
Cadorex 300 mg/ml Solution for Injection for Cattle, Sheep and Pigs
POM-VIndustrial Veterinaria SA
Fenflor 300 mg/ml Solution for Injection for Cattle
POM-VKRKA, d.d., Novo mesto
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