POM-V Prescription Required

Flordofen 300 mg/ml Solution for Injection for Cattle and Pigs

Active ingredient: Florfenicol

Form

Injection

Species

Cattle Pigs

Manufacturer

Dopharma Research B.V.

VMD MA No.

28365/3005

What it's used for

The presence of the disease in the herd should be established before methaphylaxis. Pigs: Treatment of acute outbreaks of respiratory disease caused by str...

Full indications, dosage and side effects ↓

View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Florfenicol

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Your prescription rights → VMD register of retailers →

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Flordofen 300 mg/ml Solution for Injection for Cattle and Pigs — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

The presence of the disease in the herd should be established before
methaphylaxis.
Pigs:
Treatment of acute outbreaks of respiratory disease caused by strains of
Actinobacillus pleuropneumoniae and susceptible to
florfenicol.

Pigs: Intramuscular use.
Cattle:
Treatment
IM route: 20 mg florfenicol / kg bodyweight (1 ml of the veterinary medicinal
product/15 kg) to be administered twice 48 hours apart using a 16 gauge
needle.
SC route: 40 mg florfenicol / kg bodyweight (2 ml of the veterinary medicinal
product/15 kg) to be administered once only using a 16 gauge needle.
Metaphylaxis
SC route: 40 mg florfenicol /kg bodyweight (2 ml of the veterinary medicinal
product/15 kg) to be administered once only using a 16 gauge needle.
Pig:
15 mg florfenicol /kg bodyweight (1 ml of the veterinary medicinal product/20 kg)
by intramuscular injection twice at 48 hour intervals using a 16-gauge needle.
The dose volume given at any one injection site should not exceed 10 ml for
both routes of administration (intramuscular and subcutaneous) in cattle and 3
ml in pigs. The injection should only be given in the neck in both target species.
To ensure a correct dosage, body weight should be determined as accurately
as possible.
It is recommended to treat animals in the early stages of disease and to
evaluate the response to treatment within 48 hours after the second injection. If
clinical signs of respiratory disease persist 48 hours after the last injection or if
relapse occurs, treatment should be changed using another formulation or
another antibiotic and continued until clinical signs have resolved.
Swab septum before removing each dose. Use a dry sterile needle and syringe.
Do not broach the stopper of vial more than 25 times.

Do not use in adult bulls and boars intended for breeding purposes.
Do not use in cases of hypersensitivity to the active substance or to any of the
excipients.
AN: 00460/2023Page 2 of 7

Cattle:
AN: 00460/2023Page 3 of 7
Very rare
(<1 animal / 10,000 animals
treated, including isolated
reports):
Anaphylactic shockUndetermined frequency
(cannot be estimated from the
available data):
Reduced food intake, loose stool
Injection site inflammation
1
Quick and complete recovery upon termination of treatment.
After intramuscular and subcutaneous injection; may persist for 14 days.
Pigs:
Very common
(>1 animal / 10 animals
treated):
Diarrhoea, Anal and rectal disorder (peri-anal
and rectal erythema/oedema)
Pyrexia
2,3
, Depression
3,4
Dyspnoea
3,4
Undetermined frequency
(cannot be estimated from the
available data):
Injection site swelling
Injection site lesion
1
May affect 50% of animals. Can be observed for one week.
40⁰C.
Occurred in approximately 30% of pigs treated under field conditions;
presented a week or more after administration of the second dose.
Moderate. Associated with pyrexia.
Lasting up to 5 days.
Lasting up to 28 days.
Reporting adverse events is important. It allows continuous safety monitoring of
a veterinary medicinal product. Reports should be sent, preferably via a
veterinarian, to either the marketing authorisation holder or its local
representative or the national competent authority via the national reporting
system. See the package leaflet for respective contact details.

This veterinary medicinal product does not contain an antimicrobial
preservative.

Special precautions for safe use in the target species:
Do not administer to piglets of less than 2 kg.
Use of the veterinary medicinal product should be based on susceptibility
testing of the bacteria isolated from the animal. If this is not possible, therapy
should be based on local (regional, farm level) epidemiological information
about susceptibility of the target bacteria.
Official national and regional antimicrobial policies should be taken into account
when the veterinary medicinal product is used.
Use of the veterinary medicinal product deviating from the instructions given in
the SPC may increase the prevalence of bacteria resistant to florfenicol and
may decrease the effectiveness of treatment with other antimicrobials due to the
potential for cross-resistance.
Special precautions to be taken by the person administering the veterinary
medicinal product to animals:
People with known hypersensitivity to florfenicol, propylene glycol or
polyethylene glycols should avoid contact with the veterinary medicinal product.
Care should be taken to avoid accidental self-injection. In case of accidental
self-injection, seek medical advice immediately and show the package leaflet or
the label to the physician.
Avoid skin or eye contact with the veterinary medicinal product. In case of
contact with the skin or eyes, rinse the affected area immediately with plenty of
water. Wash the hands after use.
Laboratory studies in rabbits and rats with the excipient N-methyl pyrrolidone
have shown evidence of foetotoxic effects. Women of childbearing age,
pregnant women or women suspected of being pregnant should use the
veterinary medicinal product with serious caution to avoid accidental self-
injection.
Special precautions for the protection of the environment:
Not applicable.

interaction
None known.

Store below 25 °C.
AN: 00460/2023Page 7 of 7
Keep the vial in the outer carton in order to protect from light.

Cattle:
Meat and offal: by IM (at 20 mg/kg bodyweight, twice): 30 days
by SC (at 40 mg/kg bodyweight, once): 44 days
Milk: Not authorised for use in animals producing milk for human consumption,
including during the dry period.
Pigs:
Meat and offal: 18 days

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.