Virbamec 1.0% w/v Solution for Injection for Cattle and Swine

Cattle and swine.
5.2 Indications for use
CATTLE
Virbamec 1.0% w/v Solution for Injection for Cattle and Swine is indicated for
the treatment and control of the following species of gastro-intestinal
roundworms, lungworms, eyeworms, warbles, mites and lice.
Gastro-intestinal roundworms (adult and fourth-stage larvae):
Ostertagia ostertagi (including inhibited O.ostertagi)
Ostertagia lyrata
Haemonchus placei
Trichostrongylus axei
Trichostrongylus colubriformis
Cooperia oncophora
Cooperia punctata
AN: 01199/2023 & 01202/2023
Cooperia pectinata
Bunostomum phlebotomum
Oesophagostomum radiatum
Strongyloides papillosus (adult)
Nematodirus helvetianus (adult)
Nematodirus spathiger (adult)
Trichuris spp. (adult)
Lungworms (adult and fourth-stage larvae):
Dictyocaulus viviparus
Eyeworms (adult) :
Thelazia
(parasitic stages):
Hypoderma bovis
Hypoderma lineatum
Mange mites:
Psoroptes bovis
Sarcoptes scabei var. bovis
Sucking lice:
Linognathus vituli
Haematopinus eurysternus
Solenopotes capillatus
Virbamec 1.0% w/v Solution for Injection for Cattle and Swine may also be
used as an aid in the control of the biting louse Damalinia bovis and the
mange mite Chorioptes bovis, but complete elimination may not occur.
Persistent activity in cattle
When cattle have to graze on pasture contaminated with infective larvae of
cattle nematodes, treatment with Virbamec 1.0% w/v Solution for Injection for
Cattle and Swine at the recommended dose rate controls re-infection with
Cooperia spp., Haemonchus placei and Trichostrongylus axei for up to 14
days after treatment, Ostertagia ostertagi and Oesophagostomum radiatum
acquired up to 21 days and Dictyocaulus viviparus acquired up to 28 days
after treatment.
To obtain optimal benefit from the persistent activity of Virbamec1.0% w/v
Solution for Injection for Cattle and Swine, it is recommended that calves which
are set-stocked in their first grazing season should be treated 3, 8 and 13
weeks after the day of turn-out. This can protect the animals from parasitic
gastro-enteritis and lungworm disease throughout the grazing season provided
they are set-stocked, all the calves are included in the programme and that no
AN: 01199/2023 & 01202/2023
untreated cattle are added to the pasture. Treated animals should always be
monitored according to good husbandry practices.
SWINE
Virbamec 1.0% w/v Solution for Injection for Cattle and Swine is indicated for
the treatment and control of the following species of gastro-intestinal
roundworms, lungworms, mites and lice.
Internal parasites
Gastro-intestinal roundworms (adult and fourth-stage larvae):
Ascaris suum
Oesophagostomum spp.
Hyostrongylus rubidus
Strongyloides ransomi (adults and somatic larval stages)
Lungworms:
Metastrongylus spp. (adults)
External parasites
Mites:
Sarcoptes scabei var. suis
Lice:
Haematopinus suis
Virbamec 1.0% w/v Solution for Injection for Cattle and Swine may also be
used as an aid in the control of adult whipworm (Trichuris suis).
5.3 Contra-indications
Do not use by the intravenous or intramuscular route.
Do not use in cattle producing milk for human consumption.
Not for use in species other than cattle and swine as severe adverse reactions
including fatalities in dogs may occur.
5.4 Undesirable effects
At therapeutic doses, ivermectin has no adverse effect on cattle or swine since
it does not readily penetrate their central nervous systems.
Transitory discomfort has been observed in some cattle and pigs following
subcutaneous administration.
A low incidence of soft tissue swelling at the injection site has been observed
in both species. These reactions have disappeared without treatment.
AN: 01199/2023 & 01202/2023
5.5 Special precautions for use
As this product does not contain any antimicrobial preservative, swab septum
before removing each dose.
Use sterile needle and syringe.
When using the 200 ml, 500 ml and 1000 ml pack sizes, use only automatic-
syringe equipment.
5.6 Use during pregnancy and lactation
Studies have shown a wide safety margin and, at the recommended dosage,
no adverse effect on breeding performance were observed.
Do not use in non-lactating dairy cows including pregnant heifers within 60
days of calving.
5.7 Interaction with other medicaments and other forms of interaction
None known.
5.8 Posology and method of administration
CATTLE
To be given only by subcutaneous injection at the recommended dosage level
of 2 mg ivermectin per 10 kilogram bodyweight (equivalent to 1 ml per 50 kg
bodyweight) under the loose skin in front of or behind the shoulder. Each ml
contains 10 mg of ivermectin.
Dosage schedule for cattle
Bodyweight (kg)Dose volume (ml)Up to 501.051-100 2.0101-150 3.0151-200 4.0201-250 5.0251-300