POM-V Prescription Required

Veteglan 0.075 mg/ml Solution for Injection for Cows, Sows and Mares

Active ingredient: d-Cloprostenol

Form

Injection

Species

Cattle Horses Pigs

Manufacturer

Laboratorios Calier, SA

VMD MA No.

20634/5004

What it's used for

Cows • • • • luteum and pyometra. • • • • administration of GnRH or analogue) Sows • Mares • Revised: March 2025 AN: 02319/2024

Full indications, dosage and side effects ↓

View official SPC (PDF)

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Paying less for d-Cloprostenol

1

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2

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Clinical information

Veteglan 0.075 mg/ml Solution for Injection for Cows, Sows and Mares — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 26 Mar 2026.

Cows
•
•
•
•
luteum and pyometra.
•
•
•
•
administration of GnRH or analogue)
Sows
•
Mares
•

Revised: March 2025
AN: 02319/2024

For intramuscular use.
Cows: 2 ml of the product / animal (equivalent to 150 µg d-Cloprostenol /animal)
Induction of oestrus (also in cows showing weak or silent heat): Administer the
product after determination of the presence of a functional (6
th
to
th
day of cycle). Heat usually appears within 48-60 hours. Proceed to
insemination 72-96h after treatment. If there is no sign of oestrus, the treatment
may be repeated 11 days after the first injection.
Induction of parturition: administer the product after the 270
th
day of gestation.
Parturition usually takes place within 30-60 hours after treatment.
Synchronisation of oestrus: administer the product twice (within an interval of 11
days). Proceed with inseminations 72h and 96 h after the second injection.
Ovarian dysfunction
the corpus luteum. Then, proceed to inseminate at the first oestrus after injection.
If oestrus does not take place, conduct a further gynaecological examination, and
repeat the injection 11 days after the first administration. Insemination must
always be carried out 72-96 hours after injection.

Revised: March 2025
AN: 02319/2024
Clinical endometritis with the presence of a functional corpus luteum, pyometra:
administer one dose of the product. If necessary, repeat the treatment after 10
days.
Mummified foetus: Administer one dose of the product. Expulsion of the foetus is
observed within 3-4 days after administration of the product.
Induction of abortion: administer one dose of the product in the first half of
pregnancy.
Delayed uterine involution: administer one dose of the product and, if needed,
carry out one or two further treatments (within an interval of 24 hours).
Therapy for the treatment of ovarian cysts (9-14 days after initial administration
of GnRH or analogue)
positive response to treatment with GnRH or analogue.
Sows:
Mares:
The rubber stopper of the vial can be safely punctured up to 20 times. When treating
groups of animals in one run, use a draw-off needle that has been placed in the vial
stopper to avoid excess broaching of the stopper. The draw-off needle should be
removed after treatment.

Do not use in pregnant animals unless it is desirable to induce parturition or
interruption of pregnancy.
Do not use in animals with spastic dysfunctions of the gastrointestinal tract and/or
respiratory system.
Do not use in cows or sows who may have a dystocic parturition due to abnormal
position of a foetus, mechanical obstruction, etc.
Do not use in animals suffering cardiovascular or respiratory diseases.
Do not use by intravenous route.
Do not use in case of hypersensitivity to the active substance or to any of the
excipients.

Target species: Cows
Undetermined frequency:Injection site anaerobic infections (swelling
and crepitus)
Retained placenta
1
Anaerobic infection is common if anaerobic bacteria penetrate the tissue of the
infection site. This applies especially to intramuscular injection and in particular
to cows.
Depending on the timing of treatment relative to the date of conception, the
placental retention rate can be increased when used for induction of parturition.
Target species: Sows
Undetermined frequency:Injection site anaerobic infections (swelling
and crepitus)
Retained placenta
Behavioural changes
1
Anaerobic infection is common if anaerobic bacteria penetrate the tissue of the
infection site. This applies especially to intramuscular injection and in particular
to cows.
Depending on the timing of treatment relative to the date of conception, the
placental retention rate can be increased when used for induction of parturition.
Behavioural changes seen after treatment for induction of farrowing which are
similar to those changes associated with natural farrowing and usually cease
within 1 hour.
Target species: Mares
Undetermined frequency:Injection site anaerobic infections (swelling
and crepitus)
Retained placenta
Sweating
3,4
Increased respiratory rate
Increased heart rate
Abdominal discomfort
, diarrhoea
4,5
Depression
1
Anaerobic infection is common if anaerobic bacteria penetrate the tissue of the
infection site. This applies especially to intramuscular injection and in particular
to cows.

Revised: March 2025
AN: 02319/2024
Depending on the timing of treatment relative to the date of conception, the
placental retention rate can be increased when used for induction of parturition.
Occurring within 20 minutes of treatment.
When exceptionally high doses are given and are usually mild and transient.
Watery
Reporting adverse events is important. It allows continuous safety monitoring of
a veterinary medicinal product. Reports should be sent, preferably via a
veterinarian, to either the marketing authorisation holder or its local
representative or the national competent authority via the national reporting
system. See also the last section of the package leaflet for respective contact
details.

The response of cows to the synchronisation protocols is not homogeneous
between herds, nor within the same herd, and may vary depending on the
physiological state of the animal at the time of treatment (sensitivity and a functional
state of the

i) Special precautions for use in animals
Induction of parturition and abortion may increase the risk of complications, retained
placenta, foetal death and metritis.
To reduce the risk of anaerobic infections, which might be related to the
pharmacological properties of prostaglandins, care should be taken to avoid
injection through contaminated areas of skin. Clean and disinfect injection sites
thoroughly before administration.
In case of oestrus induction in cows: from the 2
nd
day after injection, adequate heat
detection is necessary.
Induction of parturition in sows before day 114 of gestation may result in an
increased risk of stillbirths and the need for manual assistance at farrowing.
ii)
veterinary medicinal product to animals
Prostaglandins of the F2
bronchospasm or miscarriage.
Take care to avoid self-injection or skin contact when handling the product.
Pregnant women, women of child-bearing age, asthmatics and people with
bronchial or other respiratory problems, should avoid contact with, or wear
disposable impervious gloves when administering the product.
Accidental spillage on the skin should be washed off immediately with soap and
water.
In case of accidental self-injection or shortness of breath resulted from accidental
inhalation or injection, seek medical advice immediately and show the package
leaflet or label to the physician.

Revised: March 2025
AN: 02319/2024
Do not eat, drink or smoke while handling the product.
Special precautions for the protection of the environment:
Not applicable.

Keep the vial in the outer carton in order to protect from light
The veterinary medicinal product does not require any special temperature storage
conditions.

Revised: March 2025
AN: 02319/2024

Cattle: meat and offal: zero days
milk: zero hours
Pigs: meat and offal: 1 day
Horses: meat and offal: 2 days
milk: zero hours
5.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.