Tribamec Duo 50 mg/ml & 1 mg/ml Oral Suspension for Sheep

Care should be taken to avoid the following practices because they increase the risk
of development of resistance and could ultimately result in ineffective therapy:
•
over an extended period of time.
•
misadministration of the product or lack of calibration of the dosing
device (if any).
Suspected clinical cases of resistance to anthelmintics should be further investigated
using appropriate tests (e.g. Faecal Egg Count reduction Test). Where the results of
the test(s) strongly suggest resistance to a particular anthelmintic, an anthelmintic
belonging to another pharmacological class and having a different mode of action
should be used.
Resistance to ivermectin has been reported in
and
reported in
Therefore, the use of this product should be based upon local (regional, farm)
epidemiological information about susceptibility of the target parasites and
recommendations on how to limit further selection for resistance to anthelmintics.

i. Special precautions for use in animals
Extra-label use in dogs should be avoided as severe adverse reactions may occur. In
common with other avermectins, certain breeds of dogs, such as Collies are especially
sensitive to ivermectin and particular care should be taken to avoid accidental
consumption of the product.
ii. Special precautions to be taken by the person administering the
medicinal product to animals
•
avoid contact with the product.
•

Amended pages: December 2025
AN: 01695/2025
•
•
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water. Take off any contaminated clothes.
•
•
iii. Other precautions
Ivermectin is highly toxic to aquatic organisms, and ivermectin and triclabendazole
are highly toxic to dung flies and beetles. Long-term effects on dung insects caused
by continuous or repeated use cannot be excluded.

The risk to aquatic ecosystems and dung fauna can be reduced by avoiding too
frequent and repeated use of this product and other products of the same
anthelmintic class in cattle, sheep and pigs. Therefore, the repetition of treatment in
a pasture during a season should be performed only in the absence of alternative
treatment and on veterinary advice.