Supaverm Oral Suspension
Active ingredients: Closantel, Mebendazole
Form
Liquid
Species
Manufacturer
Elanco GmbH
VMD MA No.
52127/3017
What it's used for
For the control of fascioliasis (due to and cestodes in sheep and lambs. The combination is active against lungworm, roundworms, tapeworms (heads and segme...
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Supaverm Oral Suspension — SPC Details
Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.
and cestodes in sheep and lambs. The combination is active against lungworm,
roundworms, tapeworms (heads and segments) and fluke (mature and immature).
For the control of the larval stages of
For the control of inhibited, immature and adult stages of
Pole worm) including benzimidazole resistant strains.
Also effective against benzimidazole susceptible strains of the following:
Gastro-intestinal roundworms
Cooperia
ovis
Lungworm
Tapeworm
Revised: April 2025
AN: 04322/2024
Fluke activity:
Stage Percentage kill
Adults 97-100 %
6-8 weeks immature 91-95 %
5 weeks immature 91 %
3-4 weeks immature 23-73 %
Ticks (
viable eggs.
mebendazole).
For example:
Bodyweight Dose
Up to 5 kg 1 ml
6-10 kg 2 ml
11-20 kg 4 ml
21-30 kg 6 ml
31-40 kg 8 ml
41-50 kg 10 ml
51-60 kg 12 ml
61-70 kg 14 ml
71-80 kg 16 ml
Revised: April 2025
AN: 04322/2024
Give orally as a drench by careful administration with a drenching gun. Suitable for use
with most types of standard drenching equipment. To ensure administration of a correct
dose, body weight should be determined as accurately as possible; accuracy of the
dosing device should be checked.
Shake container well before each use. Do not mix with other products.
Gastrointestinal worms
The frequency of treatment will depend on the level of pasture contamination. A suggested
programme is to treat ewes prior to lambing, 6 weeks after lambing and prior to tupping to
reduce pasture contamination. Dose lambs at regular intervals during high risk periods.
Rams may be treated at any time as necessary.
H. contortus
For the treatment and prevention of inhibited, immature and adult stages of benzimidazole
resistant and susceptible
contamination by infected ewes. Treat all animals at 6 weekly intervals during high risk
periods in summer and autumn.
Fluke
All sheep on infested pasture should be dosed at regular intervals during the fluke season
(Sept-Mar).
Since closantel has been shown to delay egg-laying for up to 13 weeks after artificial
infection, treatment intervals of 10-12 weeks throughout the fluke season are
recommended. In severe fluke seasons, more frequent dosing may be necessary.
The treatment of ewes with a single dose in the spring will contribute to reducing pasture
contamination during the following summer and autumn.
Any sheep brought in from fluke areas should be dosed before they join the flock.
development of resistance and could ultimately result in ineffective therapy:
•
extended period of time.
•
misadministration of the product, or lack of calibration of the dosing device (if any).
Suspected clinical cases of resistance to anthelmintics should be further
investigated using appropriate tests (e.g. Faecal Egg Count Reduction Test).
Where the results of the test(s) strongly suggest resistance to a particular
anthelmintic, an anthelmintic belonging to another pharmacological class and
having a different mode of action should be used.
Resistance to benzimidazoles (which includes mebendazole) has been reported
in Teladorsagia, Haemonchus, Cooperia and Trichostrongylus species in small
ruminants in a number of countries including the EU. Resistance to closantel has
been reported in Haemonchus in sheep outside the EU. Therefore the use of this
product should be based on local (regional, farm) epidemiological information
about susceptibility of nematodes and recommendations on how to limit further
selection for resistance to anthelmintics
To reduce the risk of anthelmintic resistance, dosing programmes should be
discussed with a veterinary surgeon.
i. Special precautions for use in animals
As overdosage may result in signs of toxicity such as incoordination and blindness, care
should be taken to ensure animals are not overdosed by volume. If the product is
spilled, care should be taken to ensure animals do not ingest it.
ii. Special precautions to be taken by the person administering the veterinary
medicinal product to animals
This product may be irritating to skin and eyes and users should be careful not to
accidentally splash it on themselves or others. Wear impermeable rubber gloves
when applying the product. Remove any contaminated clothing immediately.
Revised: April 2025
AN: 04322/2024
In case of accidental spillage onto skin or into eyes, rinse the affected area with
large amounts of clean water. If irritation persists, seek medical advice immediately
and show the package leaflet or label to the physician.
This product may be toxic after accidental ingestion. Avoid ingestion by hand-to-
mouth contact. Do not eat, drink or smoke whilst handling the product. If accidental
ingestion occurs, seek medical attention and show the package leaflet or label to
the physician. Wash hands after use.
iii. Other precautions
This product is toxic to aquatic organisms and dung insects. Long-term effects on
dung insects caused by continuous or repeated use cannot be excluded. Repeat
treatments on a pasture within a season should only be given on the advice of the
prescriber.To reduce the risk for dung fauna, if the worming protocol allows,
treated and untreated animals should be grazed on the same field. The risk to
aquatic ecosystems will be reduced by keeping treated animals away from water
bodies for 48 hours after treatment.
4.9 Amounts to be administered and administration route
1 ml per 5 kg bodyweight (ie 10 mg/kg bodyweight closantel and 15 mg/kg bodyweight
mebendazole).
For example:
Bodyweight Dose
Up to 5 kg 1 ml
6-10 kg 2 ml
11-20 kg 4 ml
21-30 kg 6 ml
31-40 kg 8 ml
41-50 kg 10 ml
51-60 kg 12 ml
61-70 kg 14 ml
71-80 kg 16 ml
Revised: April 2025
AN: 04322/2024
Give orally as a drench by careful administration with a drenching gun. Suitable for use
with most types of standard drenching equipment. To ensure administration of a correct
dose, body weight should be determined as accurately as possible; accuracy of the
dosing device should be checked.
Shake container well before each use. Do not mix with other products.
Gastrointestinal worms
The frequency of treatment will depend on the level of pasture contamination. A suggested
programme is to treat ewes prior to lambing, 6 weeks after lambing and prior to tupping to
reduce pasture contamination. Dose lambs at regular intervals during high risk periods.
Rams may be treated at any time as necessary.
H. contortus
For the treatment and prevention of inhibited, immature and adult stages of benzimidazole
resistant and susceptible
contamination by infected ewes. Treat all animals at 6 weekly intervals during high risk
periods in summer and autumn.
Fluke
All sheep on infested pasture should be dosed at regular intervals during the fluke season
(Sept-Mar).
Since closantel has been shown to delay egg-laying for up to 13 weeks after artificial
infection, treatment intervals of 10-12 weeks throughout the fluke season are
recommended. In severe fluke seasons, more frequent dosing may be necessary.
The treatment of ewes with a single dose in the spring will contribute to reducing pasture
contamination during the following summer and autumn.
Any sheep brought in from fluke areas should be dosed before they join the flock.
4.10 Overdose (symptoms, emergency procedures, antidotes), if necessary
Symptoms of serious closantel overdosage are decreased vision or blindness, anorexia,
in-coordination and general weakness.
4.11 WITHDRAWAL PERIOD(S)
Sheep (Meat): 65 days
Not authorised for use in ewes producing milk for human consumption including during
the dry period. Do not use within 1 year prior to the first lambing in ewes intended to
produce milk for human consumption.
Revised: April 2025
AN: 04322/2024
5.
This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.
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Other Products Containing Closantel
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