Skip to content
AVM-GSL Over the Counter Companion Animal

RSPCA FleaAway 268 mg Spot-On Solution for Large Dogs

Active ingredient: Fipronil

Form

Spot-on

Species

Dogs

Manufacturer

KRKA, d.d., Novo mesto

VMD MA No.

01656/4080

What it's used for

Treatment of flea (Ctenocephalides spp.) and tick (Dermacentor reticulatus) infestations. For treatment of Trichodectes canis are killed within 2 days. Ins...

Full indications, dosage and side effects ↓
View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Fipronil

  1. 1

    Ask your vet for a written prescription

    They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.

  2. 2

    Fill it at a registered online retailer

    The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Clinical information

RSPCA FleaAway 268 mg Spot-On Solution for Large Dogs — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 26 Mar 2026.

Treatment of flea (Ctenocephalides spp.) and tick (Dermacentor reticulatus)
infestations.
For treatment of Trichodectes canis
are killed within 2 days.
Insecticidal efficacy against new infestations with adult fleas persists for up to 8
weeks.
The product has a persistent acaricidal efficacy for up to 3 weeks against
Ixodes ricinus and up to 4 weeks against Rhipicephalus sanguineus and
Dermacentor reticulatus. If ticks of some species (Ixodes ricinus, Rhipicephalus
sanguineus) are present when the product is applied, all the ticks may not be
killed within the first 48 hours.

Revised: July 2019
AN: 01291/2018
Route of administration and dosage:
External use only.
Administer by topical application to the skin according to the bodyweight as
follows:
1 pipette of 2.68 ml per dog weighing over 20 kg and up to 40 kg bodyweight.
Method of administration:
Remove the pipette from the triplex bag. Hold the pipette in an upright position,
twist and pull the cap off. Turn the cap around and place the other end of the
cap back on the pipette. Push and twist the cap to break the seal, then remove
the cap from the pipette. Spread the animal hairs in the area between the
shoulder blades to make the skin visible. Put the tip of the pipette onto the skin
and press the unit-dose pipette several times to empty its contents directly onto
the skin at one or two spots.
It is important to make sure that the product is applied to an area where the
animal cannot lick it off, and to make sure that animals do not lick each other
following treatment.
The hair should be parted and the product applied to the skin. Temporary
changes to the coat (clumped/greasy hair and/or deposits on the hair) may be
noted at the application site.
Treatment schedule:
For optimal control of flea and/or tick infestation the treatment schedule can be
based on the local epidemiological situation.
In the absence of safety studies, the minimum treatment interval is 4 weeks.

Revised: July 2019
AN: 01291/2018
Do not use on puppies less than 2 months old and/or weighing less than 2 kg in
the absence of available data.
Do not use on sick (e.g. systemic diseases, fever…) or convalescent animals.
Do not use in rabbits, due to a risk of adverse drug reactions or even death.
This product is specifically developed for dogs. Do not use in cats, as this could
lead to overdosing.
Do not use in known cases of hypersensitivity to the active substance, dimethyl
sulphoxide or to any of the other excipients.
If licking occurs, a brief period of hypersalivation may be observed.
Very rarely transient cutaneous reactions on the application site (skin
discoloration, local alopecia, pruritus, erythema) and general pruritus or
alopecia have been reported after use. Hypersalivation, reversible neurologic
symptoms (hyperesthesia, depression, nervous symptoms), vomiting or
respiratory symptoms have also been observed very rarely after use.
The frequency of adverse reactions is defined using the following convention:
- very common (more than 1 in 10 animals treated displaying adverse
reaction(s))
- common (more than 1 but less than 10 animals in 100 animals treated)
- uncommon (more than 1 but less than 10 animals in 1,000 animals treated)
- rare (more than 1 but less than 10 animals in 10,000 animals treated)
- very rare (less than 1 animal in 10,000 animals treated, including isolated
reports).

Revised: July 2019
AN: 01291/2018
Bathing/immersion in water within two days after application of the product
should be avoided. After weekly immersions in water for one minute the period
of persistent insecticidal efficacy against fleas was 7 weeks.
The product does not prevent ticks from attaching to the animals. If the animal
has been treated prior to exposure to the ticks, the ticks will be killed in the first
24-48 hours after attachment. This will usually be prior to engorgement,
minimising but not excluding the risk of transmission of diseases. Once dead,
ticks will often drop off the animal, but any remaining ticks may be removed with
a gentle pull.
Fleas from pets often infest the animal's basket, bedding and regular resting
areas such as carpets and soft furnishings which should be treated, in case of
massive infestation and at the beginning of the control measures, with a
suitable insecticide and vacuumed regularly.
For optimal control of flea infestation in multi-pet household, all dogs and cats in
the household should be treated with a suitable insecticide.

i) Special precautions for use in animals
Animals should be weighed accurately prior to treatment.
Avoid contact with the animal's eyes. In the case of accidental eye contact,
immediately and thoroughly flush the eyes with water.
It is important to make sure that the product is applied to an area where
the animal cannot lick it off and to make sure that animals do not lick each
other following treatment.
Do not apply the product on wounds or damaged skin.

Revised: July 2019
AN: 01291/2018
ii) Special precautions to be taken by the person administering the
veterinary medicinal product to animals
This product can cause mucous membrane and eye irritation. Therefore,
contact between the product and the mouth or eyes should be avoided.
In the case of accidental eye contact, immediately and thoroughly flush the
eyes with water. If eye irritation persists seek medical advice and show the
package leaflet or the label to the physician.
Do not smoke, drink or eat during application.
Avoid contents coming into contact with the fingers. If this occurs, wash off
immediately with soap and water.
Wash hands after use.
People with a known hypersensitivity to fipronil or dimethyl sulphoxide or
other excipients should avoid contact with the veterinary medicinal
product.
Treated animals should not be handled until the application site is dry, and
children should not be allowed to play with treated animals until the
application site is dry. It is therefore recommended that animals are not
treated during the day, but should be treated during the early evening, and
that recently treated animals should not be allowed to sleep with owners,
especially children.
Ingestion of the product is harmful. Prevent children getting access to the
pipettes. Keep pipettes in the original packaging and discard the used
pipettes immediately after applying the product. In case of accidental
ingestion of product seek medical advice immediately.
iii) Other precautions
Fipronil may adversely affect aquatic organisms. Dogs should not be
allowed to swim in water courses for 2 days after application.
None known.
Store in the original container in order to protect from light and moisture.
The product should be maintained at room temperature (above 14°C) for
approximately one hour prior to administration.
Not applicable.
5.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.

Medication costs adding up?

Pet insurance can cover prescription medications. Find the right policy for your pet.

Compare insurance

Related Conditions

Find cheaper vets near you

Compare vet consultation prices in your area. Save on procedures and get a prescription to buy medications online.