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POM-V Prescription Required

Readycef 50 mg/ml Suspension for Injection for Pigs and Cattle

Active ingredient: Ceftiofur

Form

Injection

Species

Cattle Pigs

Manufacturer

Laboratorios Calier, S.A.

VMD MA No.

20634/4003

What it's used for

Swine: -, Actinobacillus pleuropneumoniae hydrochloride. Cattle: - haemolytica (formerly somni (former sensitive to ceftiofur hydrochloride. - with Porphyr...

Full indications, dosage and side effects ↓
View official SPC (PDF)

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Paying less for Ceftiofur

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Prescription required

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Clinical information

Readycef 50 mg/ml Suspension for Injection for Pigs and Cattle — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 26 Mar 2026.

Swine:
-,
Actinobacillus pleuropneumoniae
hydrochloride.
Cattle:
-
haemolytica (formerly
somni (former sensitive to ceftiofur hydrochloride.
-
with Porphyromonas
asaccharolytica) sensitive to ceftiofur hydrochloride.
-
within 10 days after calving associated with ,
and
restricted to cases where treatment with another antimicrobial has failed.
Swine:
3 mg ceftiofur /kg bw/day for 3 days by intramuscular injection, i.e. 1 ml of the veterinary
medicinal product /16 kg bw / day.
Cattle:
Treatment of respiratory disease: 1 mg ceftiofur /kg bw/day for 3 to 5 days by
subcutaneous injection, i.e. 1 ml of the veterinary medicinal product /50 kg bw / day.
Treatment of acute interdigital necrobacillosis: 1 mg ceftiofur /kg bw/day for 3 days by
subcutaneous injection, i.e. 1 ml of the veterinary medicinal product /50 kg bw / day.
Acute post-partum metritis within 10 days after calving: 1 mg ceftiofur / kg bw / day for 5
consecutive days by subcutaneous injection, i.e. 1 ml of the veterinary medicinal product /
50 kg bw/ day.
Subsequent injections must be given at different sites.
In case of acute post-partum metritis, additional supportive therapy might be required in
some cases.
Before use shake the bottle for a minute or until the product appears adequately
resuspended.
To ensure a correct dosage body weight should be determined as accurately as possible
to avoid underdosing.
100 ml vials can only be broached a maximum of 20 times. 250 ml vials can only be
broached a maximum of 50 times.
Do not administer to an animal previously found to be hypersensitive to ceftiofur and other
ß-lactam antibiotics or to any of the excipients.
Do not use in case of known resistance to the active substance or to other beta-lactam
antibiotics.
Do not inject intravenously.
Do not use in poultry (including eggs) due to risk of spread of antimicrobial resistance to
humans.
In swine, mild reactions at the injection site, such as discoloration of the fascia or fat, have
been observed in some animals for up to 20 days after injection.
In cattle, mild inflammatory reactions at the injection site, such as tissue oedema and
discoloration of the subcutaneous tissue and/or fascial surface of the muscle may be
observed. Clinical resolution is reached in most animals by 10 days after injection although
slight tissue discoloration may persist for 28 days or more.
Hypersensitivity reactions unrelated to dose can occur. Allergic reactions (e.g. skin
reactions, anaphylaxis) may occasionally occur.
In case of the occurrence of allergic reaction the treatment should be withdrawn.
None known.

Revised: January 2016
AN: 01262/2015

Special precautions for use in animals
The product
betalactamases (ESBL) and may constitute a risk to human health if these strains
disseminate to humans e.g. via food. For this reason, the product
the treatment of clinical conditions which have responded poorly, or are expected to
respond poorly (refers to very acute cases when treatment must be initiated without
bacteriological diagnosis) to first line treatment. Official, national and regional antimicrobial
policies should be taken into account when the product is used. Increased use, including
use of the product deviating from the instructions given in the SPC, may increase the
prevalence of such resistance. Whenever possible, the product
on susceptibility testing.
The product
prevention or as a part of heard health programmes. Treatment of groups of animals
should be strictly restricted to ongoing disease outbreaks according to the approved
conditions of use.
Do not use as prophylaxis in case of retained placenta.
Special precautions to be taken by the person administering the veterinary
medicinal product to animals
Penicillins and cephalosporins may cause hypersensitivity (allergy) following injection,
inhalation, ingestion or skin contact. Hypersensitivity to penicillins may lead to cross
reactions to cephalosporins and vice versa. Allergic reactions to these substances may
occasionally be serious.
In case of hypersensitivity or if you have been warned not to use these products any
contact with the product should be avoided.
Take care to avoid accidental self injection.
In the case of self-injection or following exposure and development of symptoms such as
skin rash, seek medical advice immediately and show the package leaflet to the physician.
Swelling of the face, lips or eyes or difficulty with breathing are more serious symptoms
and require urgent medical attention.
The bactericidal properties of are neutralised by simultaneous use of
bacteriostatic antibiotics (macrolides, sulphonamides and tetracyclines)..
Do not store above 25º C.
Do not refrigerate or freeze
Keep the vial in the outer carton in order to protect from light
Swine: Meat and offal: 5 days.
Cattle: Meat and offal: 8 days.
Milk: zero days.
5.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.

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