Cefokel 50 mg/ml, Suspension for Injection for Pigs and Cattle
Active ingredient: Ceftiofur
Form
Injection
Species
Manufacturer
Kela – Kempisch Laboratorium – Kela Laboratoria nv
VMD MA No.
06126/4007
What it's used for
Infections associated with bacteria sensitive to ceftiofur: In pigs: For the treatment of bacterial respiratory disease associated with multocida, and Stre...
Full indications, dosage and side effects ↓The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.
Paying less for Ceftiofur
-
1
Ask your vet for a written prescription
They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
-
2
Fill it at a registered online retailer
The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.
Done — we'll email you when prices land.
Prescription required
Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.
Cefokel 50 mg/ml, Suspension for Injection for Pigs and Cattle — SPC Details
Source: VMD Summary of Product Characteristics (SPC). Last updated 26 Mar 2026.
In pigs:
For the treatment of bacterial respiratory disease associated with
multocida, and Streptococcus suis.
In cattle:
For the treatment of bacterial respiratory disease associated with
haemolytica (previously ), and
Histophilus somni (previously Haemophilus somnus).
For the treatment of acute interdigital necrobacillosis (panaritium, foot rot),
associated with and
(Porphyromonas asaccharolytica).
For treatment of the bacterial component of acute post-partum (puerperal) metritis
within 10 days after calving associated with ,
pyogenes and , sensitive to ceftiofur. The indication is
restricted to cases where treatment with another antimicrobial has failed.
Revised: October 2022
AN: 01661/2022
3 mg ceftiofur/kg bw/day for 3 days via intramuscular route, i.e. 1 ml/16 kg bw at
each injection.
Cattle:
Respiratory disease: 1 mg ceftiofur/kg bw/day for 3 to 5 days by subcutaneous
injection, i.e. 1 ml/50 kg bw at each injection.
Acute interdigital necrobacillosis: 1 mg/kg bw/day for 3 days by subcutaneous
injection, i.e. 1 ml/50 kg bw at each injection.
Acute post-partum metritis within 10 days after calving: 1 mg/kg bw/day for 5
consecutive days by subcutaneous injection, i.e. 1 ml/50 kg bw at each injection.
Revised: October 2022
AN: 01661/2022
Before use, shake the bottle vigorously for at least 30 seconds until the product
appears adequately resuspended. Following shaking the bottle should be visually
examined to ensure that the product is brought back into suspension. The
absence of settled material can be confirmed by inverting the vial and viewing
the contents through the base of the vial.
The recommended maximum volume to be administered at a single injection site
is 4 ml in pigs and 6 ml in cattle. Subsequent injections must be given at
different sites.
The vial cannot be broached more than 66 times.
In case of acute post-partum metritis, additional supportive therapy might be
required in some cases.
Do not inject intravenously.
Do not use in cases where resistance to other cephalosporins or -lactam antibiotics
has occurred.
Do not use in poultry (including eggs) due to risk of spread of antimicrobial resistance
to humans.
skin reactions, anaphylaxia) may occasionally occur. In case of the occurrence of
allergic reaction the treatment should be withdrawn.
In pigs, mild reactions at the injection site, such as discoloration of the fascia or
fat, have been observed in some animals for up to 20 days after injection.
In cattle, mild inflammatory reactions at the injection site, such as tissue oedema
and discoloration of the subcutaneous tissue and/or fascial surface of the muscle
may be observed. Clinical resolution is reached in most animals by 10 days after
injection although slight tissue discoloration may persist for 28 days or more.
The frequency of adverse reactions is defined using the following convention:
- very common (more than 1 in 10 animals treated displaying adverse reaction(s))
- common (more than 1 but less than 10 animals in 100 animals treated)
- uncommon (more than 1 but less than 10 animals in 1,000 animals treated)
- rare (more than 1 but less than 10 animals in 10,000 animals treated)
- very rare (less than 1 animal in 10,000 animals treated, including isolated reports).
Special precautions for use in animals
This veterinary medicinal product does not contain any antimicrobial preservative.
The product selects for resistant strains such as bacteria carrying extended spectrum
betalactamases (ESBL) and may constitute a risk to human health if these strains
disseminate to humans e.g. via food. For this reason, the product should be reserved
for the treatment of clinical conditions which have responded poorly, or are expected
to respond poorly (refers to very acute cases when treatment must be initiated
without
bacteriological diagnosis) to first line treatment. Official, national and regional
antimicrobial policies should be taken into account when the product is used.
Increased use, including use of the product deviating from the instructions given in
the SPC, may increase the prevalence of such resistance.
Whenever possible, the product should only be used based on susceptibility testing.
The product is intended for treatment of individual animals. Do not use for disease
prevention or as a part of herd health programs. Treatment of groups of animals
should be strictly restricted to ongoing disease outbreaks according to the approved
conditions of use.
Do not use as prophylaxis in case of retained placenta.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
Penicillins and cephalosporins may cause hypersensitivity (allergy) following
injection, inhalation, ingestion or skin contact. Hypersensitivity to penicillins may
lead to cross reactions to cephalosporins and vice versa. Allergic reactions to
these substances may occasionally be serious.
Do not handle this product if you know you are sensitised, or if you have been
advised not to work with such preparations.
Handle this product with great care to avoid exposure. Wash hands after use.
Revised: October 2022
AN: 01661/2022
If you develop symptoms following exposure such as a skin rash, you should
seek medical advice and show the doctor this warning.
Swelling of the face, lips or eyes or difficulty with breathing are more serious
symptoms and require urgent medical attention.
bacteriostatic antibiotics (macrolides, sulphonamides and tetracyclines).
Keep the vial in the outer carton in order to protect from light.
Meat and offal: 5 days.
Cattle:
Meat and offal: 8 days.
Milk: zero hours
5.
This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.
Medication costs adding up?
Pet insurance can cover prescription medications. Find the right policy for your pet.
Related Conditions
Other Products Containing Ceftiofur
These products share the same active ingredient and may be suitable alternatives. Always consult your vet.
Actionis 50 mg/ml, Suspension for Injection for Pigs and Cattle
POM-VLaboratorios SYVA S.A.
Actionis 50 mg/ml, Suspension for Injection for Pigs and Cattle
POM-VLaboratorios SYVA S.A.
Cefavex 50 mg/ml Suspension for Injection for Pigs and Cattle
POM-VSP Veterinaria, S.A.
Ceftiosan, 50 mg/ml, Suspension for Injection for Pigs and Cattle
POM-VAlfasan Nederland B.V.
Cemay 50 mg/ml Suspension for Injection for Pigs and Cattle
POM-VLaboratorios Maymo S.A.U.
Cevaxel-RTU 50 mg/ml, Suspension for Injection for Cattle and Pigs
POM-VCeva Sante Animale
Alternative options to consider
Retailers we earn a commission from. It costs you nothing and never changes what we show.
The Pharm Pet Co. — Pet Pharmacy
UK online pet pharmacy. Flea, worm, prescription medications, supplements and pet food. Save vs vet prices.
Pet Care at Pharmacy2U
The UK's largest online pharmacy. Pet wormers, flea treatments, dental and joint care. Free delivery on orders over £30.
KatKin Fresh Cat Food
The UK's top-rated cat food. 100% fresh, human-quality meat, gently cooked and delivered frozen. Vet-formulated for every life stage.
We may earn a small commission if you purchase through these links, at no extra cost to you.
Related Medications
Actionis 50 mg/ml, Suspension for Injection for Pigs and Cattle
POM-VCeftiofur
Actionis 50 mg/ml, Suspension for Injection for Pigs and Cattle
POM-VCeftiofur
Adaxio Shampoo for Dogs
POM-VChlorhexidine Gluconate + Miconazole Nitrate
Adaxio Shampoo for Dogs
POM-VChlorhexidine Gluconate + Miconazole Nitrate
Advocin 180, 180 mg/ml, Solution for Injection for Cattle
POM-VDanofloxacin
Aivlosin 42.5 mg/g Oral Powder for Pigs
POM-VTylvalosin
Find cheaper vets near you
Compare vet consultation prices in your area. Save on procedures and get a prescription to buy medications online.