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POM-V Prescription Required Companion Animal

PROPALIN, 40.28 mg/ml, Syrup for Dogs

Active ingredient: Phenylpropanolamine

Form

Syrup

Species

Dogs

Manufacturer

Vetoquinol UK Limited

VMD MA No.

08007/5019

What it's used for

Efficacy has only been demonstrated in ovariohysterectomised bitches.

Full indications, dosage and side effects ↓
View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Phenylpropanolamine

  1. 1

    Ask your vet for a written prescription

    They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.

  2. 2

    Fill it at a registered online retailer

    The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

PROPALIN, 40.28 mg/ml, Syrup for Dogs — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

Efficacy has only been demonstrated in ovariohysterectomised bitches.
To ensure a correct dosage, body weight should be determined as accurately as
possible.
The recommended dose for the veterinary medicinal product is 1mg/kg bodyweight 3
times daily in the feed, corresponding to 0.1 ml of the veterinary medicinal product /
5 kg bodyweight (i.e., a graduation of the provided syringe for 5 kg), 3 times daily.
The absorption rate is increased if the veterinary medicianal product is administered
to fasted dogs.
AN: 02470/2025Page 4 of 6
The use of the veterinary medicinal product is not appropriate for the treatment of
behavioural causes of inappropriate urination. Do not use in patients treated with
non-selective monoamine oxidase inhibitors.
Do not use in cases of hypersensitivity to the active substance or to any of the
excipients.
Dogs:
Rare
(1 to 10 animals / 10,000 animals treated):
Diarrhoea
, loose stool, emesis
Lethargy
Very rare
(<1 animal / 10,000 animals treated,
including isolated reports):
Tachycardia
, high blood pressure
(hypertension
), arrhythmia
Proteinuria
Wobbliness, ataxia, seizure
Decreased appetite
Collapse, polydipsia
Aggression, hyperactivity (agitation)
Hypersensitivity
Polyuria
Liquid
Effects of sympathomimetics producing excessive stimulation of the sympathetic
nervous system.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian,
to either the marketing authorisation holder or the national competent authority via
the national reporting system. See the package leaflet for respective contact details.
None.
AN: 02470/2025Page 2 of 6

Special precautions for safe use in the target species:
Due to the very low doses to be administered, and to avoid any risk of overdose, the
animal must be weighed, and the recommended doses must be respected.
Phenylpropanolamine, a sympathomimetic drug, may affect the cardiovascular
system, especially blood pressure and heart rate, and should be used with caution in
animals with cardiovascular diseases.
Care should be exercised in treating animals with severe renal or hepatic
insufficiency, diabetes mellitus, hyperadrenocorticism, glaucoma, hyperthyroidism or
other metabolic disorders.
In bitches less than 1 year old the possibility of anatomical disorders contributing to
incontinence should be considered prior to treatment.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
Phenylpropanolamine Hydrochloride is toxic when overdoses are ingested. Adverse
effects may include dizziness, headache, nausea, insomnia or restlessness, and
increased blood pressure. High overdose may be fatal, especially in children.
To avoid accidental ingestion, the veterinary medicinal product must be used and
kept out of reach of children. Always replace the cap secure after use.
In case of accidental ingestion, seek medical advice immediately and show the
package leaflet or the label to the physician.
In case of accidental skin contact, wash the contaminated area with soap and water.
Wash hands after use of the veterinary medicinal product.
In case of accidental eye contact, rinse the eye with clean water for about 15
minutes and seek medical advice immediately and show the package leaflet or the
label to the physician.
Special precautions for the protection of the environment:
Not applicable.
AN: 02470/2025Page 3 of 6
Care should be exercised in administering the veterinary medicinal product with
other sympathomimetic drugs, anticholinergic drugs, tricyclic antidepressants or
specific type B monoamine oxidase inhibitors.
Do not store above 25°C.
Keep the bottle in the outer carton in order to protect from light.
Not applicable.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.

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