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POM-V Prescription Required Companion Animal

Continence 40 mg/ml Syrup for Dogs

Active ingredient: Phenylpropanolamine

Form

Syrup

Species

Dogs

Manufacturer

Fatro S.p.A.

VMD MA No.

11557/3006

What it's used for

Treatment of urinary incontinence associated with urethral sphincter incompetence in the bitch. Efficacy has only been demonstrated in ovariohysterectomise...

Full indications, dosage and side effects ↓
View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Phenylpropanolamine

  1. 1

    Ask your vet for a written prescription

    They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.

  2. 2

    Fill it at a registered online retailer

    The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Continence 40 mg/ml Syrup for Dogs — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

Treatment of urinary incontinence associated with urethral sphincter incompetence in
the bitch.
Efficacy has only been demonstrated in ovariohysterectomised bitches.
Oral use.
The recommended dose for Propalin is 1mg/kg bodyweight 3 times daily in the
feed, corresponding to 0.1 ml Propalin Syrup / 5 kg bodyweight (i.e., a graduation of
the provided syringe for 5 kg), 3 times daily.
The absorption rate is increased if the product is administered to fasted dogs.
Do not administer to patients treated with non-selective monoamine oxidase inhibitors.
Do not use in cases of hypersensitivity to the active substance or to any of the excipients.
Do not administer to pregnant or lactating bitches.
Dogs:
Very rare
(<1 animal / 10,000 animals treated,
including isolated reports):
Hypersensitivity reaction.Undetermined frequency
(cannot be estimated from the
available data):
Loose stool; Diarrhoea; Decreased appetite;
Arrhythmia; Collapse;
Dizziness; Aggression; Restlessness.
*
Sympathomimetics may produce a wide range of effects, most of which mimic the results
of excessive stimulation of the sympathetic nervous system (e.g. effects on heart rate and
blood pressure).
Reporting adverse events is important. It allows continuous safety monitoring of a veterinary
medicinal product. Reports should be sent, preferably via a veterinarian, to either the
marketing authorisation holder or its local representative or the national competent authority
via the national reporting system. See the package leaflet for respective contact details.
AN: 03390/2023Page 3 of 6
The veterinary medicinal product should be avoided in hypertensive individuals.
In bitches less than 1 year old the possibility of anatomical disorders contributing to
incontinence should be considered prior to treatment.
The use of the veterinary medicinal product is not appropriate for the treatment of
behavioural causes of inappropriate urination.
AN: 03390/2023Page 2 of 6

Special precautions for safe use in the target species:
Phenylpropanolamine, a sympathomimetic drug, may affect the cardiovascular system,
especially blood pressure and heart rate, and should be used with caution in animals with
cardiovascular diseases.
Care should be exercised in treating animals with severe renal or hepatic insufficiency,
diabetes mellitus, hyperadrenocorticism, glaucoma, hyperthyroidism or other metabolic
disorders.
Special precautions to be taken by the person administering the veterinary medicinal product
to animals:
Phenylpropanolamine hydrochloride is toxic when ingested in higher doses.
Adverse effects may include dizziness, headache, nausea, insomnia or restlessness, and
increased blood pressure.
Accidental ingestion by a child may be fatal.
To avoid accidental ingestion, the veterinary medicinal product must be used and kept out
of sight and reach of children. Always replace the cap securely after use and store the
syringe and bottle inside the cardboard box at all times.
In case of accidental ingestion, seek medical attention immediately and show the package
leaflet or the label to the physician.
In the event of accidental skin contact, wash the contaminated area with soap and water.
Wash hands after handling the veterinary medicinal product.
This veterinary medicinal product may cause eye irritation. Avoid eye contact.
In case of accidental eye contact, rinse the eye thoroughly with clean water for about
15 minutes and consult a physician.
Special precautions for the protection of the environment:
Not applicable.
Care should be exercised in administering the veterinary medicinal product with other
sympathomimetic drugs, anticholinergic drugs, tricyclic antidepressants or specific type B
monoamine oxidase inhibitors.
This veterinary medicinal product does not require any special storage conditions.
Keep the bottle and the syringe in the outer carton.
Special precautions for safe use in the target species:
Phenylpropanolamine, a sympathomimetic drug, may affect the cardiovascular system,
especially blood pressure and heart rate, and should be used with caution in animals with
cardiovascular diseases.
Care should be exercised in treating animals with severe renal or hepatic insufficiency,
diabetes mellitus, hyperadrenocorticism, glaucoma, hyperthyroidism or other metabolic
disorders.
Special precautions to be taken by the person administering the veterinary medicinal product
to animals:
Phenylpropanolamine hydrochloride is toxic when ingested in higher doses.
Adverse effects may include dizziness, headache, nausea, insomnia or restlessness, and
increased blood pressure.
Accidental ingestion by a child may be fatal.
To avoid accidental ingestion, the veterinary medicinal product must be used and kept out
of sight and reach of children. Always replace the cap securely after use and store the
syringe and bottle inside the cardboard box at all times.
In case of accidental ingestion, seek medical attention immediately and show the package
leaflet or the label to the physician.
In the event of accidental skin contact, wash the contaminated area with soap and water.
Wash hands after handling the veterinary medicinal product.
This veterinary medicinal product may cause eye irritation. Avoid eye contact.
In case of accidental eye contact, rinse the eye thoroughly with clean water for about
15 minutes and consult a physician.
Special precautions for the protection of the environment:
Not applicable.
3.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.

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