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POM-V Prescription Required Companion Animal

PROPALIN, 40.28 mg/ml, Syrup for Dogs

Active ingredient: Phenylpropanolamine

Form

Syrup

Species

Dogs

Manufacturer

Vetoquinol SA

VMD MA No.

06462/3010

What it's used for

Treatment of urinary incontinence associated with urethral sphincter incompetence in the bitch. Efficacy has only been demonstrated in ovariohysterectomise...

Full indications, dosage and side effects ↓
View official SPC (PDF)

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Paying less for Phenylpropanolamine

  1. 1

    Ask your vet for a written prescription

    They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.

  2. 2

    Fill it at a registered online retailer

    The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

PROPALIN, 40.28 mg/ml, Syrup for Dogs — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 26 Mar 2026.

Treatment of urinary incontinence associated with urethral sphincter incompetence in
the bitch.
Efficacy has only been demonstrated in ovariohysterectomised bitches.
Oral use.
The recommended dose for Propalin is 1mg/kg bodyweight 3 times daily in the
feed, corresponding to 0.1 ml Propalin Syrup / 5 kg bodyweight (i.e., a graduation of
the provided syringe for 5 kg), 3 times daily.
The absorption rate is increased if the product is administered to fasted dogs.
The use of Propalin is not appropriate for the treatment of behavioural causes of
inappropriate urination. Do not administer to patients treated with non-selective
monoamine oxidase inhibitors.
Do not use in case of known hypersensitivity to active substance or to any of the
excipients.
Sympathomimetics may produce very rarely a wide range of effects, most of which
mimic the results of excessive stimulation of the sympathetic nervous system such
as effects on heart rate (tachycardia) or effects on blood pressure (increased blood
pressure), which can induce proteinuria.
Dizziness, decrease in appetite, arrhythmia, collapse, aggression, hyperactivity
(including restlessness), polydipsia, polyuria, ataxia, seizure and and
hypersensitivity may occur in very rare cases.
Liquid diarrhoea/loose stool, emesis and lethargy have been reported rarely.
The frequency of adverse reactions is defined using the following convention:
- very common (more than 1 in 10 animals treated displaying adverse reaction(s))
- common (more than 1 but less than 10 animals in 100 animals treated)
- uncommon (more than 1 but less than 10 animals in 1,000 animals treated)
- rare (more than 1 but less than 10 animals in 10,000 animals treated)
- very rare (less than 1 animal in 10,000 animals treated, including isolated reports).

Revised July 2025
AN: 01101/2025Page 3 of 5
None.

Revised July 2025
AN: 01101/2025Page 2 of 5

Special precautions for use in animals
Due to the very low doses to be administered, and to avoid any risk of overdose,
the animal must be weighed, and the recommended doses must be respected.
Phenylpropanolamine, a sympathomimetic drug, may affect the cardiovascular
system, especially blood pressure and heart rate, and should be used with caution in
animals with cardiovascular diseases.
Care should be exercised in treating animals with severe renal or hepatic
insufficiency, diabetes mellitus, hyperadrenocorticism, glaucoma, hyperthyroidism or
other metabolic disorders.
In bitches less than 1 year old the possibility of anatomical disorders contributing to
incontinence should be considered prior to treatment.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
Phenylpropanolamine Hydrochloride is toxic when overdoses are ingested. Adverse
effects may include dizziness, headache, nausea, insomnia or restlessness, and
increased blood pressure. High overdose may be fatal, especially in children.
To avoid accidental ingestion, the product must be used and kept out of reach of
children. Always replace the cap secure after use.
In the event of accidental ingestion, seek immediate medical attention showing the
physician the package insert.
In the event of accidental skin contact, wash the contaminated area with soap and
water. Wash hands after use of the product.
In the event of accidental eye contact, rinse the eye with clean water for about 15
minutes and seek medical advice.
Care should be exercised in administering Propalin Syrup with other
sympathomimetic drugs, anticholinergic drugs, tricyclic antidepressants or specific
type B monoamine oxidase inhibitors.
Do not store above 25°C.
Keep the bottle in the outer carton in order to protect from light.
Not applicable.
5.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.

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