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POM-V Prescription Required

Prid Delta 1.55 g Vaginal Delivery System for Cattle

Active ingredient: Progesterone

Form

Vaginal delivery system

Species

Cattle

Manufacturer

Ceva Sante Animale

VMD MA No.

14966/3024

What it's used for

For the control of the œstrus cycle in cows and heifers including: - Synchronisation of œstrus including fixed time artificial insemination (FTAI) protocol...

Full indications, dosage and side effects ↓
View official SPC (PDF)

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  1. 1

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  2. 2

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    The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Prid Delta 1.55 g Vaginal Delivery System for Cattle — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 26 Mar 2026.

For the control of the œstrus cycle in cows and heifers including:
- Synchronisation of œstrus including fixed time artificial insemination (FTAI) protocols.
- Synchronisation of oestrus of donor and recipient animals for embryo transfer. To be
used in combination with a prostaglandin (PGF2 or analogue)
- Induction and synchronisation of œstrus in cycling and non cycling cattle including fixed
time artificial insemination (FTAI) protocols.
-α) or analogue.
-
releasing hormone (GnRH) or analogue and PGF2α or analogue.
-α or analogue and equine
chorionic gonadotrophin (eCG).
Vaginal use.
1.55 g of progesterone / animal for 7 days.
Judgment on the protocol to be used should be made by the veterinarian responsible for
treatment, on the basis of the treatment objectives of the individual herd or cow. The
following protocols could be used.
For synchronisation of oestrus (including synchronisation of oestrus of donor and
recipients animal for embryo transfer)
• Insert the device for 7 days.
• Inject a prostaglandin (PGF2 α) or analogue 24 hours prior to device removal
• Removal of the device
• In animals that respond to treatment the onset of oestrus generally occurs within 1-3
days after removal of the device. Cows should be inseminated within 12 hours of first
observed oestrus.
For the induction and synchronisation of oestrus for Fixed Time Artificial Insemination
(FTAI)
The following FTAI protocols have been commonly reported in the literature:
In cycling cattle:
• Insert the device for 7 days.
• Inject a prostaglandin (PGF2 α) or analogue 24 hours prior to device removal
• Removal of the device
• Animals should be inseminated 56 hours after removal of the device.
In cycling and non-cycling cattle (including recipient cows):
• Insert the device for 7 days.
• Inject GnRH or analogue at the device insertion.
• Inject a prostaglandin (PGF2 α) or analogue 24 hours prior to device removal
• Animals should be inseminated 56 hours after removal of the device, or
• Inject GnRH or analogue 36 hours after device removal and FTAI 16 to 20 hours later.
Or in alternative,
• Insert the device for 7 days.
• Inject GnRH or analogue at the device insertion
• At device removal inject prostaglandin (PGF2 α) or analogue
• Inject GnRH or analogue 56 hours after removal of the device
• Animals should be inseminated 16 to 20 hours later
In non-cycling cattle:
• Insert the device for 7 days.
• Inject a prostaglandin (PGF2 α) or analogue 24 hours prior to device removal
• Inject eCG at the time of the device removal
• Animals should be inseminated 56 hours after removal of the device.
Device application information:
Using an applicator, insert one device into the vagina of the animal. The intravaginal
device should stay in place for 7 days.
The device is intended for single use only.

Revised: September 2025
AN: 01712/2025
Applicator method of use and Insertion:
A device applicator should be used for administration, following the procedure described
below:
1. Clean and disinfect the applicator in a non-irritant antiseptic solution before use.
2. Fold the device and load into the applicator. The end of the device tail should be
outside of the applicator. Care should be taken to avoid unnecessary or prolonged
handling of the product to minimise transfer of the active substance to the operator's
gloves.
3. Apply a small quantity of obstetrical lubricant to the end of the loaded applicator.
4. Lift the tail and clean the vulva and perineum.
5. Gently insert the applicator into the vagina, first in a vertical direction and then
horizontally until some resistance is encountered.
6. Make sure the removal tail is free, press the handle of the applicator and pull it out,
leaving the removal tail hanging from the vulva.
7. Clean and disinfect the applicator after use and before use on another animal.
Removal:
Remove 7 days after insertion by gently pulling on the removal tail. On occasions the tail
may not be visible from the outside of the animal, in such cases it may be located in the
posterior vagina using a gloved finger. Withdrawal of the device should not require force. If
any resistance is encountered a gloved hand should be used to ease removal.
If there is any difficulty in removal from the animal beyond that itemised above veterinary
advice must be sought.
Do not use in sexually immature heifers or females with abnormal genital tracts e.g.
freemartins.
Do not use before 35 days have passed since previous calving.
Do not use in animals suffering from infectious or non-infectious disease of the genital
tract.
Do not use in pregnant animals. See section 4.7.

Revised: September 2025
AN: 01712/2025
During the course of the seven day treatment, the device may induce a mild local reaction
(i.e. inflammation of the vaginal wall). A clinical study carried out with 319 cows and heifers
has demonstrated that 25% of animals presented ropy or cloudy vulvar secretions at the
device removal. This local reaction disappears rapidly without any treatment between
removal and insemination and does not affect fertility at inseminations nor pregnancy
rates.
The frequency of adverse reactions is defined using the following convention:
- very common (more than 1 in 10 animals treated displaying adverse reaction(s))
- common (more than 1 but less than 10 animals in 100 animals treated)
- uncommon (more than 1 but less than 10 animals in 1,000 animals treated)
- rare (more than 1 but less than 10 animals in 10,000 animals treated)
- very rare (less than 1 animal in 10,000 animals treated, including isolated reports).
The percentage of cows displaying oestrus within a given period following treatment is
usually greater than in untreated cows and the subsequent luteal phase is of normal
duration. However, the progesterone treatment alone, according to dosage regimen
proposed, is not sufficient to induce oestrus and ovulation in all cycling females.
In order to optimise the protocol, it is advisable to determine cycling ovarian activity before
using the progesterone treatment.
Animals in poor condition, whether from illness, inadequate nutrition, under unnecessary
stress or other factors, may respond poorly to treatment.

Special precautions for use in animals
It is recommended to wait a minimum of 35 days following parturition before starting the
treatment with this product.
Special precautions to be taken by the person administering the veterinary medicinal
product to the animals
Gloves must be worn when handling the veterinary medicinal product both during insertion
and removal.
Do not eat or drink when handling the veterinary medicinal product.
Wash hands after use.
None known.

Revised: September 2025
AN: 01712/2025
This veterinary medicinal product does not require any special storage conditions.
horizontally until some resistance is encountered.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.

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