POM-V Prescription Required

ACEGON 50 micrograms/ml Solution for Injection for Cattle

Active ingredient: Gonadorelin

Form

Injection

Species

Cattle

Manufacturer

Laboratorios SYVA S.A.

VMD MA No.

31592/4005

What it's used for

In association with artificial insemination to optimise the time of ovulation. Induction and synchronisation of oestrus and ovulation in combination with p...

Full indications, dosage and side effects ↓

View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Gonadorelin

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

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Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

ACEGON 50 micrograms/ml Solution for Injection for Cattle — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

In association with artificial insemination to optimise the time of ovulation.
Induction and synchronisation of oestrus and ovulation in combination with
prostaglandin F2 (PGF2α) with or without progesterone as part of Fixed Time
Artificial Insemination (FTAI) protocols:
-In cycling cows. To be used in combination with PGF2α or analogue.
-In cycling and non-cycling cows and heifers. To be used in combination with PGF2α
or analogue and progesterone releasing device.
AN: 00588/2025 & 00589/2025

•: 100-150 micrograms of gonadorelin (as
acetate) per animal (i.e. 2- 3 ml of the veterinary medicinal product per animal). If
necessary, treatment can be repeated at intervals of 1-2 weeks.
•
improving the chances that the treated cow will become fertile:
micrograms of gonadorelin (as acetate) per animal (i.e. 2 ml of the veterinary
medicinal product per animal). It must be administered at the same time as artificial
insemination and/or 12 days after this.
The following timing of injection and insemination should be followed:
-
-
insemination is recommended.
AN: 00588/2025 & 00589/2025
-
recommendations, i.e., 12 to 24 hours after oestrus detection.
Induction and synchronisation of oestrus and ovulation in combination with
prostaglandin F2 (PGF2α) with or without progesterone as part of Fixed Time
Artificial Insemination (FTAI) protocols:
The following FTAI protocols have been commonly reported in the literature:
In cycling cows:
•
ml of the veterinary medicinal product)
• 2α or analogue (luteolytic dose)
•
ml of the veterinary medicinal product)
•
Alternatively:
•
ml of the veterinary medicinal product)
• 2α or analogue (luteolytic dose)
•
acetate) per animal (2 ml of the veterinary medicinal product) 60–72
hours later, or at observed oestrus if sooner.
In cycling and non-cycling cows and heifers:
•
•
the veterinary medicinal product) at progesterone device insertion.
• 2α or analogue 24 hours prior to device
removal.
•
•
the veterinary medicinal product) 36 hours after progesterone
releasing device removal and FTAI 16 to 20 hours later.
AN: 00588/2025 & 00589/2025

Do not use in cases of hypersensitivity to the active substance or to any excipients.
Do not use for shortening of oestrus during infectious diseases and other relevant
disorders.

None known.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or its local representative or the national
competent authority via the national reporting system. See the package leaflet for
respective contact details.

In the treatment of cystic ovaries, the condition of ovarian follicular cysts should be
diagnosed by rectal palpation revealing the presence of persisting follicular structures
with a diameter over 2.5 cm and should be confirmed by the use of plasma or milk
progesterone assay.
The veterinary medicinal product should be administered at least 14 days after calving
due to the absence of receptivity of the hypophysis before that time.
For induction and synchronisation of oestrus and ovulation in Fixed Time Artificial
Insemination (FTAI) protocols, the veterinary medicinal product should be
administered at least 35 days after calving. The response of cows and heifers to
synchronisation protocols is influenced by the physiological state at the time of
treatment. Responses to treatment can vary either across herds or across cows within
herds. However, the percentage of cows displaying oestrus within a given period is
usually greater than in untreated cows and the subsequent luteal phase is of normal
duration.
For protocol that only includes PGF2 recommended for cycling cows: To maximise
conception rates of cows to be treated, the ovarian status should be determined and
regular cyclic ovarian activity confirmed. Optimal results will be achieved in healthy
normally-cycling cows.

Special precautions for safe use in the target species:
Animals in poor condition, whether from illness, inadequate nutrition, or other factors,
may respond poorly to treatment.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
Gonadorelin is a Gonadotropin Releasing Hormone (GnRH) analogue which
stimulates the release of sex hormones. The effects of accidental exposure to GnRH
analogues in pregnant women or in women with normal reproductive cycles are
unknown; therefore, it is recommended that pregnant women should not administer
the product and that women of child-bearing age should administer the veterinary
medicinal product with caution.
Care should be taken when handling the veterinary medicinal product to avoid self-
injection. In case of accidental self-injection, seek medical advice immediately and
show the package leaflet or the label to the physician.
Since GnRH analogues can be absorbed through the skin and benzyl alcohol may
cause mild local irritation, care should be taken to avoid skin and eye contact. In case
of skin and/or eyes contact, rinse immediately and thoroughly with plenty of water.
AN: 00588/2025 & 00589/2025
GnRH analogues and benzyl alcohol may cause hypersensitivity (allergy). People
with known hypersensitivity to GnRH analogues or benzyl alcohol, should avoid
contact with the veterinary medicinal product.
Special precautions for the protection of the environment:
Not applicable.

A synergistic effect occurs in case of combined administration of FSH.

Do not store above 25 ºC.

Meat and offal: Zero days.
Milk: Zero hours.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.