POM-V Prescription Required

Chronogest CR, 20 mg Controlled Release Vaginal Sponge for Sheep

Active ingredient: Flugestone Acetate

Form

Vaginal sponge

Species

Sheep

Manufacturer

Intervet International B.V.

VMD MA No.

06376/3003

What it's used for

Full indications, dosage and side effects ↓

View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Flugestone Acetate

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Your prescription rights → VMD register of retailers →

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Chronogest CR, 20 mg Controlled Release Vaginal Sponge for Sheep — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

The sponge is inserted intra-vaginally using an applicator.
Duration of sponge residence is 14 days. At the end of the administration period, the
sponge is gently removed by pulling on its string.
To obtain an optimal synchronization of ovulation, an intra-muscular injection of PMSG
(range 300-700 IU) is recommended (i.m.) at the time of sponge removal.
In case fixed time artificial insemination is applied, it is recommended to perform it 55
h after sponge removal.

None.

Sheep (ewe and ewe lamb).
Very rare
(<1 animal / 10,000 animals
treated, including isolated
reports):
Vaginal discharge
1
muco-purulent discharge may be observed at sponge removal. It is not associated
with clinical signs and does not alter fertility.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder <or its local representative> or the national
competent authority via the national reporting system. See also section “Contact
details” of the package leaflet.

Amended pages: March 2025

None.

Amended pages: March 2025

Special precautions for safe use in the target species:
-
appearance of PMSG antibodies in some ewes. This in turn may affect the time
of ovulation and result in reduced fertility when combined with fixed time
artificial insemination at 55h following sponge removal.
-
-
recommended to correctly insert sponges and to avoid vaginal injuries.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
Personal protective equipment consisting of single use gloves should be worn when
handling the veterinary medicinal product.
The veterinary medicinal product should not be administered by pregnant women or
women suspected to be pregnant.
Direct contact with the skin should be avoided.
If accidental contact with the skin occurs, wash the affected zone with soap and water.
Wash hands
after treatment and before meals.
Human exposure to this product can affect fertility.
Special precautions for the protection of the environment:
Not applicable.

The sponges should not be used in conjunction with alcohols, cresols, phenols, sheep
dips or similar disinfectants.

Store below 25 C.
Store in the original package.
Store in a dry place.
Once packaging is opened, any unused product should be discarded.

Meat and offal: 2 days after withdrawal of sponges.
Milk: zero hours, including the treatment time.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.