POM-V Prescription Required Companion Animal

Busol - 0.004 mg/ml Solution for Injection for Cattle, Horses, Rabbits

Active ingredient: Buserelin

Form

Injection

Species

Cattle Horses Rabbits

Manufacturer

aniMedica GmbH

VMD MA No.

24745/4000

What it's used for

on breeding conditions. In horses: - Induction of ovulation to synchronise ovulation more closely with mating - Improvement of conception rate AN: 01413/20...

Full indications, dosage and side effects ↓

View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Buserelin

1

Ask your vet for a written prescription

They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
2

Fill it at a registered online retailer

The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

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Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Busol - 0.004 mg/ml Solution for Injection for Cattle, Horses, Rabbits — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

on breeding conditions.
In horses:
- Induction of ovulation to synchronise ovulation more closely with mating
- Improvement of conception rate
AN: 01413/2024 & 01414/2024Page 2 of 6In rabbits:
- Improvement of conception rate
- Induction of ovulation in post partum insemination.

The dose per animal is 10 to 20 µg buserelin in cows, 20 to 40 µg buserelin in mares and
0.8 µg buserelin in rabbits.
Species / Indicationml of the veterinary
medicinal product
µg
Buserelin
Cattle
Fertility disorders of ovarian origin, in
particular:
Follicular cysts with or without
symptoms of nymphomania
5 ml20 µgEarly cycle induction post partum5 ml20 µgImprovement of conception rate in
artificial insemination procedures,
also after synchronisation of oestrus
with a PGF2α analogue.
(Results may however vary
depending on breeding conditions)
2.5 ml10 µg
Mares
Induction of ovulation to synchronise
ovulation more closely with mating.
(If ovulation has not occurred within
24 hours after treatment, then the
injection should be repeated.)
10 ml40 µgImprovement of conception rate10 ml40 µg
Rabbits
For improving the conception rate0.2 ml0.8 µgInduction of ovulation in post partum
insemination
0.2 ml0.8 µg
This veterinary medicinal product is preferably given by intramuscular injection. The
intravenous or subcutaneous route may also be used. The veterinary medicinal product
should be administered once.

None.

None known.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or its local representative or the national
competent authority via the national reporting system. See the package leaflet for
respective contact details.

Treatment with a Gonadotropin releasing hormone (GnRH) analogue is only symptomatic;
the causes underlying a fertility disorder are not eliminated by this treatment.

Special precautions for safe use in the target species:
Observe aseptic precautions.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
Avoid eye and skin contact with the solution for injection. In case of accidental eye contact,
rinse thoroughly with water. Should skin contact with the veterinary medicinal product
occur, wash the exposed area immediately with soap and water, as GnRH analogues may
be absorbed through the skin.
Pregnant women should not administer the veterinary medicinal product, as buserelin has
been shown to be foetotoxic in laboratory animals. When administering the veterinary
medicinal product, care should be taken to avoid accidental self-injection by ensuring that
animals are suitably restrained and the application needle is shielded until the moment of
injection. Women of child-bearing age should administer the veterinary medicinal product
with caution. In case of accidental self-injection, seek medical advice immediately and
show the package leaflet or the label to the physician.
Special precautions for the protection of the environment:
Not applicable.

No data available.

Do not store above 25 C.

Cattle, horses, rabbits
Meat and offal Zero days
Cattle, horses
Milk Zero hours

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.