PREVEXXION RN+HVT+IBD Concentrate and Solvent for Suspension for Injection
Active ingredients: Marek's disease virus, Turkey herpesvirus
Form
Injection
Species
Manufacturer
Boehringer Ingelheim Vetmedica GmbH
VMD MA No.
61700/5041
What it's used for
Onset of immunity: MD: 5 days post-hatch. IBD: 14 days post-hatch (subcutaneous) or 28 days post-hatch (in ovo). Duration of immunity:MD: A single vaccinat...
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1
Ask your vet for a written prescription
They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.
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2
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The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.
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Prescription required
Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.
PREVEXXION RN+HVT+IBD Concentrate and Solvent for Suspension for Injection — SPC Details
Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.
IBD: 14 days post-hatch (subcutaneous) or 28 days post-hatch (in
ovo).
Duration of immunity:MD: A single vaccination is sufficient to provide protection for the
entire risk period.
IBD: 10 weeks post-hatch.
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the liquid nitrogen. The exact amount of vaccine ampoules and amount of solvent
needed shall be calculated first according to the table below provided as example:
Amended pages: January 2026
Solvent bag
Number of vaccine
ampoules
(subcutaneous use)
Number of vaccine
ampoules
(in ovo use)
1 bag of 200 ml
solvent
1 ampoule (1 000 doses)
4 ampoules (1 000 doses)
or 2 ampoules
(2 000 doses)
or 1 ampoule (4 000 doses)
1 bag of 400 ml
solvent
2 ampoules (1 000 doses)
or 1 ampoule
(2 000 doses)
8 ampoules (1 000 doses)
or 4 ampoules
(2 000 doses)
or 2 ampoules
(4 000 doses)
1 bag of 800 ml
solvent
4 ampoules (1 000 doses)
or 2 ampoules
(2 000 doses)
or 1 ampoule
(4 000 doses)
16 ampoules (1 000 doses)
or 8 ampoules
(2 000 doses)
or 4 ampoules
(4 000 doses)
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used immediately.
•
25 °C ─
immediately to the next step.
•
open them while holding them at arm’s length (in order to prevent injury if any
ampoule breaks).
•
ampoules that are thawed, and fit it with a needle of 18 gauge or larger.
•
through the septum of one of the bag-connecting tubes and withdraw 2 ml of
solvent.
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Do this by slowly drawing up the contents from each ampoule by gently tilting the
ampoule forward and inserting the needle with the bevel edge facing downwards
towards the bottom of the ampoule. Continue until all the vaccine is drawn out of
the ampoule.
•
cloudy).
•
•
volume of the solvent containing the vaccine into the syringe. Then slowly fill the
ampoule bodies and tips with it. Withdraw the content from the ampoule bodies
and tips, and inject it back into the solvent bag.
•
Amended pages: January 2026
•
number of ampoules to be diluted in the solvent bag.
•
immediately. During vaccination, gently swirl the bag frequently to ensure the
vaccine remains homogenously mixed.
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within two hours. Do not freeze it under any circumstances. Do not re-use opened
containers of vaccine.
Posology:
One single injection of 0.2 ml per one-day-old chick or 0.05 ml per 18-day-old
embryonated chicken egg.
Method of administration:
The vaccine must be administered by subcutaneous injection in the neck or by
injection.
None.
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or its local representative or the national
competent authority via the national reporting system. See the package leaflet for
respective contact details.
Chickens with maternally derived antibodies against MD when vaccinated with this
veterinary medicinal product, may have a delayed onset of immunity against IBD.
Special precautions for safe use in the target species:
Apply the usual aseptic precautions to all administration procedures.
As this is a live vaccine, both vaccine strains may be excreted from vaccinated birds.
The RN1250 vaccine strain has not been shown to spread in experimental conditions.
The vHVT013-69 vaccine strain may be spread to unvaccinated chickens and turkeys.
Appropriate veterinary and husbandry measures should be taken to avoid spread of the
vaccine strains to unvaccinated chickens, turkeys and other susceptible species.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
Personal protective equipment consisting of gloves, spectacles and boots should be
worn when handling the veterinary medicinal product, before withdrawing from liquid
nitrogen, during the ampoule thawing and opening operations. Frozen glass ampoules
may explode during sudden temperature changes. Store and use liquid nitrogen only in
a dry and well-ventilated place. Inhalation of the liquid nitrogen is dangerous.
Amended pages: January 2026
Special precautions for the protection of the environment:
Not applicable.
any other veterinary medicinal product. A decision to use this vaccine before or after
any other veterinary medicinal product therefore needs to be made on a case-by-case
basis.
Store and transport frozen in liquid nitrogen.
The liquid nitrogen containers must be checked regularly for liquid nitrogen level and
must be refilled as needed.
Discard any ampoules that have been accidentally thawed.
Solvent:
Store below 30 °C. Do not freeze. Protect from light.
This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.
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Other Products Containing Marek's disease virus
These products share the same active ingredient and may be suitable alternatives. Always consult your vet.
Cevac MD Rispens Concentrate and Solvent for Suspension for Injection for Chickens
POM-VCeva Animal Health Ltd
Nobilis Rismavac + CA126 Concentrate and Solvent for Suspension for Injection for Chickens
POM-VPSIntervet International B.V.
Nobilis Rismavac Concentrate and Solvent for Suspension for Injection for Chickens
POM-VPSIntervet International B.V.
Poulvac Marek CVI + HVT Concentrate and Solvent for Suspension for Injection for Chickens
POM-VPSZoetis UK Limited
Poulvac Marek CVI Concentrate and Solvent for Suspension for Injection
POM-VPSZoetis UK Limited
PREVEXXION RN Concentrate and Solvent for Suspension for Injection
POM-VBoehringer Ingelheim Vetmedica GmbH
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