Cevac MD Rispens Concentrate and Solvent for Suspension for Injection for Chickens

The vaccine may be injected by automatic syringe. Overview table for recommended
dilution possibilities of different presentations:
Cevac MD Rispens
No. of ampoules x
doses (D)
Solvent
presentation
(ml)
Volume of one dose
(ml)
1 x 1,000 D2001 x 2,000 D4002 x 2,000 D8001 x 4,000 D8004000 + 1000 D10003 x 2000 D12002 x 4000 D1600
0.20
Overview table for recommended dilution possibilities of different presentations in case of
associated use:
No. of ampoules x doses (D)
Cevac MD RispensVectormune ND
Solvent
presentation
(ml)
Volume of one
dose
(ml)
1 x 1,000 D1 x 1,000 D2001 x 2,000 D1 x 2,000 D4002 x 2,000 D2 x 2,000 D8001 x 4,000 D1 x 4,000 D8004000 + 1000 D4000 + 1000 D10003 x 2000 D3 x 2000 D12002 x 4000 D2 x 4000 D1600
0.20
The usual aseptic precautions should be applied to all administration procedures.
Be familiar with all safety and precautionary measures for handling liquid nitrogen in
order to prevent personal injury.
Reconstitution of the vaccine:
- Use
ampoules with the solvent size, quickly remove the exact number of ampoules
needed from the liquid nitrogen container.
- Draw up 2 ml of solvent into a 5 ml syringe. Use minimum 18 gauge needle. In case
of associated use different syringe should be used for each vaccine.
- Thaw rapidly the contents of the ampoules by gentle agitation in water at 27-39°C.
- As soon as they are completely thawed, open ampoules holding them at arm length
in order to prevent any risk of injury should the ampoule break.
- Once the ampoule is open, slowly draw up the content into the 5-ml sterile syringe
prepared as in point 2.
- Transfer the thawed suspension into the solvent bag. The reconstituted vaccine
prepared as described is mixed by gentle agitation.
- Withdraw a portion of the diluted vaccine from the solvent bag into the syringe and
use it to rinse the ampoule. Inject it gently back into the solvent bag. Repeat once or
twice.
- The reconstituted vaccine prepared as described is mixed by gentle agitation so as
to be ready for use.
Repeat the operations in point 2-7 for the appropriate number of ampoules to be
thawed.
Use the reconstituted vaccine immediately, slowly mix regularly to ensure uniform
suspension of cells and use within a period not exceeding 2 hours.
It should be ensured that the diluted vaccine is mixed regularly in a gentle way during the
vaccination session to guarantee that the vaccine remains homogenous and that the
correct virus titer is administered during vaccination session.