Noromectin 0.08% w/v Drench Oral Solution

Care should be taken to avoid the following practices because they increase the
risk of development of resistance and could ultimately result in ineffective
therapy:
Too frequent and repeated use of anthelmintics from the same class, over an
extended period of time
Underdosing, which may be due to underestimation of body weight,
misadministration of the product, or lack of calibration of the dosing device (if
any)
Suspected clinical cases of resistance to anthelmintics should be further
investigated using appropriate tests (e.g. Faecal Egg Count Reduction Test).
Where the results of the test(s) strongly suggest resistance to a particular
anthelmintic, an anthelmintic belonging to another pharmacological class and
having a different mode of action should be used.
Resistance to ivermectin (an avermectin) has been reported in
sheep and goats within the EU and it is common in in sheep
outside the EU. Therefore the use of this product should be based on local
(regional, farm) epidemiological information about susceptibility of nematodes
and recommendations on how to limit further selection for resistance to
anthelmintics.

i. Special precautions for use in animals
None
ii. Special precautions to be taken by the person administering the veterinary
medicinal product to animals
Do not smoke, drink or eat while handling the product.
Avoid contact with skin and eyes. In case of accidental eye or skin contact,
wash the affected area with clean running water immediately. Seek
medical attention if irritation persists.
Wash hands after use.

Revised: August 2010
(Amended pages)