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POM-V Prescription Required

Naxcel 200 mg/ml Suspension for Injection for Cattle

Active ingredient: Ceftiofur

Form

Injection

Species

Cattle

Manufacturer

Zoetis UK Limited

VMD MA No.

42058/5041

What it's used for

Treatment of acute interdigital necrobacillosis in cattle also known as panaritium or foot rot. Treatment of acute post-partum (puerperal) metritis in catt...

Full indications, dosage and side effects ↓
View official SPC (PDF)

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Paying less for Ceftiofur

  1. 1

    Ask your vet for a written prescription

    They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.

  2. 2

    Fill it at a registered online retailer

    The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Naxcel 200 mg/ml Suspension for Injection for Cattle — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 27 Mar 2026.

Treatment of acute interdigital necrobacillosis in cattle also known as panaritium or foot
rot.
Treatment of acute post-partum (puerperal) metritis in cattle, in cases where treatment
with another antimicrobial has failed.
Single subcutaneous injection of 6.6 mg ceftiofur/kg body weight (equivalent to 1 ml of the
veterinary medicinal product per 30 kg body weight) administered at the base of the ear.
To ensure a correct dosage, body weight should be determined as accurately as possible.
It is recommended to limit injection volumes to a maximum of 30 ml per injection site.
Shake the bottle vigorously for 30 seconds, or until all visual settlement has been
resuspended.
Base of the ear administration:
• Administer in the posterior part of the ear base (see Figure 1).
• Hold the syringe and insert the needle behind the animal’s ear so the needle and syringe
point in the direction of an imaginary line that would pass through the head toward the
animal’s opposite eye (see Figure 2).
• Take appropriate precautions to avoid intra-arterial or intravenous injection, such as
restraining appropriately the animal (chute or head restraint for example) and using
appropriate needles [1 inch (2.54 cm) long, 16 gauge].
Figure 1. Injection location for the
subcutaneous administration of the
veterinary medicinal product at the
posterior aspect of the ear where it
attaches to the head (base of ear).
Figure 2. Subcutaneous
administration of the veterinary
medicinal product at the posterior
aspect of the ear where it
attaches to the head (base of
ear). Diagram of the head
showing the direction for the
base of the ear injections
administered toward the animal’s
opposite eye.

Issued: December 2023
AN: 03044/2022
If clinical signs have not improved 48 hours after treatment, the diagnosis and treatment of
the condition should be re-evaluated.
Do not use in cases of hypersensitivity to the active substance, to other beta-lactam
antibiotics or to any of the excipients.
Cattle:
Very common
(>1 animal / 10 animals
treated):
Injection site swelling
, Injection site pain
Very rare
(<1 animal / 10,000 animals
treated, including isolated
reports):
Anaphylaxis, Sudden death
1
Visible two days after injection in about two thirds of treated animals and resolving within
a maximum of 23 days.
Mild to moderate in the initial days following injection.
Following accidental intra-vascular administration or anaphylaxis.

Issued: December 2023
AN: 03044/2022
Reporting adverse events is important. It allows continuous safety monitoring of a
veterinary medicinal product. Reports should be sent, preferably via a veterinarian, to
either the marketing authorisation holder or its local representative or the national
competent authority via the national reporting system. See the package leaflet for
respective contact details.
None.

Special precautions for use in animals
For systemically-administered broad-spectrum cephalosporins (3
rd
and 4
th
generation,
such as ceftiofur), it should be reflected that these are to be reserved for the treatment of
clinical conditions which have responded poorly, or are expected to respond poorly, to less
critical antimicrobials. Increased use, including use of the product deviating from the

Issued: December 2023
AN: 03044/2022
instructions given in the Summary of Product Characteristics (SPC), may increase the
prevalence of bacteria resistant to ceftiofur. Official, national and regional antimicrobial
policies should be taken into account when the product is used.
Whenever possible, the veterinary medicinal product should only be used based on
susceptibility testing. When considering the treatment strategy, it is appropriate to consider
improvement of the herd management practice and use supporting treatment with suitable
local products (e.g. disinfectants).
Do not use as prophylaxis in cases of retained placenta.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals
Penicillins and cephalosporins such as ceftiofur may cause hypersensitivity in people and
in animals following injection, inhalation, ingestion or skin contact. Hypersensitivity to
penicillins may lead to cross reactions to cephalosporins and vice versa. Allergic reactions
to these substances may occasionally be serious.
People with known hypersensitivity to penicillins and cephalosporins should avoid contact
with the veterinary medicinal product.
Avoid contact with skin or eyes. In the event of contact, wash with clean water.
If you develop symptoms following exposure such as a skin rash or persistent eye
irritation, you should seek medical advice and show the package leaflet or the label to the
physician. Swelling of the face, lips or eyes or difficulty with breathing are more serious
symptoms and require urgent medical attention.
Special precautions for the protection of the environment
Not applicable
Other precautions
Not applicable.
None known.
Do not store above 25 C.
Meat and offal: 9 days.
Milk: Zero days.
It is essential that the veterinary medicinal product is only administered subcutaneously at
the base of ear location in non-edible tissue, as described in section 4.9, in order to
comply with the meat withdrawal period.
5.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.

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