Maximec Horse Oral Paste, 18.7 mg/g

Care should be taken to avoid the following practices because they increase the risk of
development of resistance and could ultimately result in ineffective therapy:
- Too frequent and repeated use of anthelmintics from the same class, over an extended
period of time.
- Underdosing, which may be due to underestimation of bodyweight or misadministration
of the veterinary medicinal product.
Suspected clinical cases of resistance to anthelmintics should be further investigated using
appropriate tests (e.g. Faecal Egg Count Reduction Test). Where the results of the test(s)
strongly suggest resistance to a particular anthelmintic, an anthelmintic belonging to
another pharmacological class and having a different mode of action should be used.
Resistance to ivermectin (an avermectin) has been reported in Parascaris equorum in
horses in a number of countries, including the EU. Therefore, the use of this veterinary
medicinal product should be based on local (regional, farm) epidemiological information
about susceptibility of nematodes and recommendations on how to limit further selection
for resistance to anthelmintics.

Special precautions for safe use in the target species:
Where there is significant tissue damage following Habronema infestation, additional
medical therapies may be required.
Dogs or cats may be adversely affected by the concentration of ivermectin in this
veterinary medicinal product if they are allowed to ingest spilled paste or have access to
used syringes.
Special precautions to be taken by the person administering the veterinary medicinal
product to animals:
Do not smoke, drink or eat while handling this veterinary medicinal product.
Wash hands after use.
Special precautions for the protection of the environment:
EXTREMELY DANGEROUS TO FISH AND AQUATIC LIFE. Do not contaminate surface
waters or ditches with the product or used container.
AN: 02512/2024 & 02516/2024