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POM-V Prescription Required Companion Animal

Lotimil 48 mg Chewable Tablets for Cats (>2.0–8.0 kg)

Active ingredient: Lotilaner

Form

Chewable

Species

Cats

Manufacturer

Elanco Europe Ltd

VMD MA No.

00879/5049

What it's used for

For the treatment of flea and tick infestations on cats. This veterinary medicinal product provides immediate and persistent killing activity for 1 month a...

Full indications, dosage and side effects ↓
View official SPC (PDF)

The prescription itself has a price. See what practices near you charge for a consultation and the written prescription fee.

Paying less for Lotilaner

  1. 1

    Ask your vet for a written prescription

    They must provide one on request. Under the CMA Order the fee is capped at £21 from 2027.

  2. 2

    Fill it at a registered online retailer

    The CMA found online pharmacies 50–60% cheaper than practice dispensing on common medicines — typically £200–£300 a year.

Prescription required

Your vet must provide a written prescription on request. You can then purchase from any licensed online retailer.

Clinical information

Lotimil 48 mg Chewable Tablets for Cats (>2.0–8.0 kg) — SPC Details

Source: VMD Summary of Product Characteristics (SPC). Last updated 26 Mar 2026.

For the treatment of flea and tick infestations on cats.
This veterinary medicinal product provides immediate and persistent killing
activity for 1 month against fleas (Ctenocephalides felis and C. canis) and ticks
(Ixodes ricinus).
Fleas and ticks must attach to the host and commence feeding in order to be
exposed to the active substance.
The veterinary medicinal product can be used as part of a treatment strategy
for the control of flea allergy dermatitis (FAD).
Do not use in cases of hypersensitivity to the active substance or to any of the
excipients.

Revised: February 2026
AN: 03359/2025
Target species: Cats
Very rare (<1 animal / 10,000 animals
treated, including isolated reports):
Hyperactivity
1,2
Vomiting
Ataxia, Muscle tremor
Tachypnoea
Pruritus
1,2

Anorexia, Lethargy
Mild and transient
Typically resolves without treatment
Reporting adverse events is important. It allows continuous safety monitoring of
a veterinary medicinal product.

Revised: February 2026
AN: 03359/2025
Reports should be sent, preferably via a veterinarian, to either the marketing
authorisation holder or the national competent authority via the national
reporting system. See also the last section of the package leaflet for respective
contact details.
Parasites need to start feeding on the host to become exposed to lotilaner;
therefore the risk of the transmission of parasite borne diseases cannot be
completely excluded.
Acceptable levels of efficacy may not be achieved if the veterinary medicinal
product is not administered with food or within 30 minutes after feeding.
Due to insufficient data to support efficacy against ticks in young cats, this
product is not recommended for the treatment of ticks in kittens 5 months of
age or younger.

i). Special precautions for use in animals
Safety and efficacy data has been studied in cats aged 8 weeks and older with
a body weight of 0.5 kg or more. Therefore, use of this veterinary medicinal
product in kittens younger than 8 weeks of age or less than 0.5 kg of body
weight should be based on a benefit-risk assessment by the responsible
veterinarian.
ii). Special precautions to be taken by the person administering the veterinary
medicinal product to animals
Wash hands after handling the product.
In case of accidental ingestion, seek medical advice immediately and show the
package leaflet or label to the physician.
iii). Other precautions
Not applicable
None known.
During clinical testing, no interactions between Lotimil chewable tablets and
routinely used veterinary medicinal products were observed.
This veterinary medicinal product does not require any special storage
conditions.
Not applicable
5.

This information is sourced from the official Summary of Product Characteristics (SPC) published by the Veterinary Medicines Directorate (VMD). It is provided for informational purposes only and does not replace professional veterinary advice. Always consult your vet before administering any medication.

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